.. Optimisation-de-la-méthode-d-'analyse, Choix du solvant de reprise, ., vol.146, issue.1483, p.151

C. Identification-et-dosage-de-b1-dans-le and L. La, 153 a) 153 b) CCAP® repris dans du méthanol) Evaluation de la perte à l'évaporation/reprise, p.156

C. Utilisation-commerciale and .. , 178 IV. Etude toxicologique de l'oléo-gommo-résine et des guggulstérones, p.178

M. Résine-de, 185 a) Première méthode, p.186

-. Bonnes-chardonnet, A. Thibaudon, and D. , Pratiques de Fabrication ; bulletin officiel N° « Le guide du PDCA de DEMING, progrès continue et management ». Paris, éditions d'organisation, p.62, 2003.

P. H. -gouch, E. Lilly, and . Company, Extraits du document AFNOR (Association Française de Normalisation), ICH Q9 « Quality Risk Management ». An Industry View [12] -Lexique définitions normalisées (ISO 9000), 2004.

A. -al-harrasi and S. Al-saidi, « Phytochemical Analysis of the Essential Oil from Botanically Certified Oleogum Resin of Boswellia sacra (Omani Luban) ». Molecules, pp.2181-2189, 2008.

H. J. Cordemoy, Octave Doin et Fils, Les Plantes à Gommes et à Résines Plant Resins : Chemistry, Evolution, Ecology, and Ethnobotany, 1911.

J. Santiago-blay and J. Lambert, « Aux sources de l'ambre : l'analyse spectroscopique des matières exsudées par les végétaux actuels constitue le fondement d'une identification chimique et botanique des ambres et des autres résines fossiles », Pour la science, vol.356, pp.70-75, 2007.

K. Konno, Plant latex and other exudates as plant defense systems: Roles of various defense chemicals and proteins contained therein, Phytochemistry, vol.72, issue.13, pp.1510-1530, 2011.
DOI : 10.1016/j.phytochem.2011.02.016

J. Phytothérapie-homéopathie-niebler and A. Buettner, Ted & Doc « Biologie végétale. Structures, fonctionnement, écologie et biotechnologies ». Traduction de Sallés G Pearson Education France « Development of essential oil industries in developing countries ». United Nations Industrial Development Organization Vienna, Frankincense Revisited, Part I : Comparative Analysis of Volatiles in Commercially Relevant Boswellia Species, pp.613-642, 1995.

H. Hussain, A. Al-harrasi, A. Al-rawahi, J. Hussain, L. O. Hanus et al., « Chemistry and Biology of Essential Oils of Genus Boswellia ». Evidence-Based Complementary and Alternative Medicine, Myrrh-Commiphora chemistry, pp.3-28, 2005.

C. André and M. L. Bettenfeld, « Applications des huiles essentielles dans le domaine des arômes et parfums La chimie des huiles essentielles : Tradition et innovation, Safety and Feasibility of Topical Application of Limonene as a Massage Oil to the Breast, pp.193-211, 2012.

J. Bruneton, J. Pharmacognosie33-]-kaloustian, and F. Hadji-minaglou, « Comparison of estimated daily intakes of flavouring substances with no-observed-effect levels », Food Chem Toxicol, vol.34, issue.446, pp.758-809, 2009.

A. Safetyherrmann, M. Lechtenberg, and A. Hensel, A Guide for Health Care Professionals, Comparative isolation and structural investigations of polysaccharides from Boswellia serrata ROXB. and Boswellia carterii BIRDW, 2007.

A. -herrmann, S. König, M. Lechtenberg, M. Sehlbach, S. Y. Vakhrushev et al., Proteoglycans from Boswellia serrata Roxb. and B. carteri Birdw. and identification of a proteolytic plant basic secretory protein, Glycobiology, vol.22, issue.11, pp.1424-1463, 2012.
DOI : 10.1093/glycob/cws107

P. Sarup, S. Bala, K. S. Malviya, R. Srivastava, P. Kulkarni et al., « Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu) ». Scientifica, Applications of Mucilages in Drug Delivery, 2011.

B. W. Tekade and Y. A. Chaudhari, « Gums and Mucilages : Excipients for modified Drug Delivery System, J. Adv. Pharm. Edu. & Res, vol.3, pp.359-367, 2013.

S. Panta, R. Malviya, and P. Sharma, « Extraction and Characterization of Boswellia Serrata Gum as Pharmaceutical Excipient », Polim Med, vol.45, issue.1, pp.25-30, 2015.

U. M. Deogade, V. N. Deshmukh, and D. M. Sakarkar, « Natural gums and gum's in NDDS : Applications and recent approaches, International Journal of PharmTech Research, vol.4, issue.2, pp.799-814, 2012.

A. Agraria, Sistemas y Recursos Forestales, pp.211-221

-. Rani, A. S. Varanasi, and . Murthy, « Natural gums : it's role as excipients and diverse applications in pharmacy ? a comprehensive review, IAJPS, Volume1, pp.502-511, 2014.

P. Kumar and I. Singh, « Evaluation of oleo-gum resin as directly compressible tablet excipient and release retardant », Acta Pol. Pharm, vol.67, issue.3, pp.307-313, 2010.

M. J. -kulshreshtha, D. K. Kulshreshtha, and R. P. Rastogi, « The triterpenoids ? a review, 1972.

P. Pani and R. P. Rastogi, « The triterpenoids -a review », Phytochemistry, vol.18, issue.7, pp.1095-1108, 1979.

M. Thulin and A. M. Warfa, The Frankincense Trees (Boswellia spp., Burseraceae) of Northern Somalia and Southern Arabia, Kew Bulletin, vol.42, issue.3, pp.487-500, 1987.
DOI : 10.2307/4110063

J. Dupéron, « 'encens et les Boswellia : Historique. Apport de l'anatomie à la systématique de trois Boswellia de Somalie et du Yémen, Revue de Cytologie et de Biologie Végétales -Le Botaniste, pp.3-4, 1993.

P. Iserin, M. Masson, and J. P. Restillini, « Larousse des plantes médicinales identification, préparation, soins, Plantes médicinales du monde réalités et croyances, 1996.

E. G. Atchley and F. Cuthbert, « A history of the use of incense in divine worship, 1909.

S. Dawson, E. R. Sailer, R. H. Hoernlein, N. Schneider, H. P. Ammon et al., Frankincense -Plant Monograph « Synthesis of a radio-iodinated photoaffinity analogue of the direct, non-redox, non-competitive 5 lipoxygenase inhibitor acetyl-11-keto-boswellic acid, Boswellia spp, p.113, 1996.

M. T. Huan, V. Badmaev, Y. Ding, Y. Liu, and J. G. Xie, « Anti-tumor and anticarcinogenic activities of triterpenoid, ß-boswellic acid, BioFactors, vol.13, pp.1-4, 2000.

Y. S. Park, J. H. Lee, J. Bondar, J. A. Safayhi, and M. Golubic, Cytotoxic Action of Acetyl-11-keto-??-Boswellic Acid (AKBA) on Meningioma Cells, Planta Medica, vol.68, issue.5, p.397401, 2002.
DOI : 10.1055/s-2002-32090

S. Basar, A. Koch, and W. A. König, « A verticillane-type diterpene from Boswellia carterii ». Flavour and Fragrance Journal, pp.315-318, 2001.

B. Büchele, W. Zugmaier, and T. Simmet, Analysis of pentacyclic triterpenic acids from frankincense gum resins and related phytopharmaceuticals by high-performance liquid chromatography. Identification of lupeolic acid, a novel pentacyclic triterpene, Journal of Chromatography B, vol.791, issue.1-2, pp.21-30, 2003.
DOI : 10.1016/S1570-0232(03)00160-0

M. L. Sharma, Effect of salai guggal ex-Boswellia serrata on cellular and humoral immune responses and leucocyte migration, Agents and Actions, vol.137, issue.1-2, pp.161-164, 1988.
DOI : 10.1111/j.2042-7158.1975.tb09439.x

H. Safayhi, « Boswellic acids : novel, specific, nonredox inhibitors of 5-lipoxygenase, 1992.

J. Bruneton, S. Singh, A. Khajuria, S. C. Taneja, R. K. Johri et al., « Pharmacognosie phytochimie plantes médicinales, Boswellic acids : A leukotriene inhibitor also effective through topical application in inflammatory disorders, 2008.

H. Safayhi, Concentration-Dependent Potentiating and Inhibitory Effects of Boswellia Extracts on 5-Lipoxygenase Product Formation inStimulated PMNL, Planta Medica, vol.66, issue.2, pp.110-113, 2000.
DOI : 10.1055/s-2000-11136

H. Safayhi, « Inhibition by boswellic acids of human leukocyte elastase, J. Pharmacol, 1997.

A. Kapil and N. Moza, Anticomplementary activity of Boswellic acids ??? An inhibitor of C3-convertase of the classical complement pathway, International Journal of Immunopharmacology, vol.14, issue.7, pp.1139-1143, 1992.
DOI : 10.1016/0192-0561(92)90048-P

N. Kimmatkar, V. Thawani, L. Hingorani, and R. Khiyani, Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee ??? A randomized double blind placebo controlled trial, Phytomedicine, vol.10, issue.1, pp.3-7, 2003.
DOI : 10.1078/094471103321648593

M. Z. Siddiqui, « Boswellia Serrata, A Potential Antiinflammatory, Indian Journal of Pharmaceutical Sciences, vol.73, issue.3, pp.255-261, 2011.

R. Etzel, Special extract of BOSWELLIA serrata (H 15) in the treatment of rheumatoid arthritis, Phytomedicine, vol.3, issue.1, 1996.
DOI : 10.1016/S0944-7113(96)80019-5

N. Kimmatkar, « Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee ». Phytomediciene, pp.3-7, 2003.

I. Gupta, « Effects of Boswellia serrata gum resin in patients with bronchial asthma : results of a double-blind, placebo-controlled, 6-week clinical study », Eur. J. Med. Res, vol.17, issue.11, pp.3-511, 1998.

S. Togni, G. Maramaldi, D. Pierro, F. Biondi, and M. , « A cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis Clinical, Cosmetic and Investigational Dermatology, pp.321-327, 2014.

I. Gupta, « Effects of Boswellia serrata gum resin in patients with ulcerative colitis, 1997.

V. Sterk, B. Büchele, and T. Simmet, Effect of Food Intake on the Bioavailability of Boswellic Acids from a Herbal Preparation in Healthy Volunteers, Planta Medica, vol.70, issue.12, pp.1155-1160, 2004.
DOI : 10.1055/s-2004-835844

-. Monographtogni, S. Maramaldi, G. Bonetta, A. Giacomelli, L. et al., Boswellia serrata Alternative Medicine Review Nutranews Science, Nutrition, Prévention et Santé « Clinical evaluation of safety and efficacy of boswellia-based cream for prevention of adjuvant radiotherapy : a randomized placebo controlled trial », Efficacité thérapeutique reconnue, pp.1338-1344, 1998.

M. Majeed and L. Prakash, « Boswellin® CG : Chemistry, toxicology and clinical ». Sabinsa Corporation, Acétyl-11-keto-?-boswellic acid : targeting oral cavity pathogens, p.406, 2007.

H. P. Ammon, T. Mack, G. B. Singh, and H. Safayhi, « Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of the gum resin exudate of Boswellia serrata, 1991.

S. A. Shah, I. S. Rathod, B. N. Suhagia, S. S. Pandya, and V. K. Parmar, A Simple High-Performance Liquid Chromatographic Method for the Estimation of Boswellic Acids from the Market Formulations Containing Boswellia serrata Extract, Journal of Chromatographic Science, vol.46, issue.8, pp.735-743, 2008.
DOI : 10.1093/chromsci/46.8.735

A. Shikov, O. Pozharitskaya, S. Ivanova, V. Makarov, and V. Kosman, « A comparison between HPLC and HPTLC for the separation and quantification of boswellic acids in Boswellia serrata extracts ». CBS, Use of fingerprinting and marker compounds for the identification and standardization of Boswellia serrata gum extract, pp.2290-2303, 2010.

M. Maheux, « Stratégies analytiques par chromatographie liquide avec détection en spectrométrie de masse afin d'évaluer l, 2012.

. Département-de-chimie, Faculté des sciences et de génie, The Latest Trend in LC Analysis: UHPLC Core?Shell Particles, 2012.

G. Culioli, C. Mathe, P. Archier, and C. Et-vieillescazes, A lupane triterpene from frankincense (Boswellia sp., Burseraceae), Burseraceae), pp.537-541, 2003.
DOI : 10.1016/S0031-9422(02)00538-1

M. Hovaneissian, P. Archier, C. Mathe, and C. Vieillescazes, Contribution de??la??chimie analytique ????l'??tude des??exsudats v??g??taux styrax, storax et??benjoin, Comptes Rendus Chimie, vol.9, issue.9, pp.1192-1202, 2006.
DOI : 10.1016/j.crci.2005.12.010

M. Hovaneissian, P. Archier, C. Mathe, G. Culioli, and C. Et-vieillescazes, Analytical investigation of styrax and benzoin balsams by HPLC??? PAD???fluorimetry and GC???MS, Phytochemical Analysis, vol.69, issue.4, pp.301-310, 2007.
DOI : 10.1002/pca.1048

L. O. Hanus, T. Rezankab, V. M. Dembitskya, and A. Moussaieffa, Myrrh - commiphora chemistry, Myrrh?Commiphora chemistry, pp.3-28, 2005.
DOI : 10.5507/bp.2005.001

URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.387.8171

P. Iserin, M. Masson, J. Restillini, F. Capasso, T. S. Gaginella et al., « Larousse des plantes médicinales identification, préparation, soins ». Paris : Larousse [102] -« Commiphora wightii ». From Wikipedia, The free encyclopedia, Plantes médicinales du monde réalités et croyances Phytotherapy : a quick reference to Herbal Medicine, 2001.

J. Bruneton, « Pharmacognosie : phytochimie, plantes médicinales, 1999.

B. Boullard, « An update review on Commiphora molmol and related species, Plantes médicinales du monde réalités et croyances ». Paris : Editions ESTEM, 2001.

P. -lefrançois, F. Ruby, C. Bertin, D. J. Carrier, P. Sarup et al., «Myrrhe» http://www.passeportsante.net/fr/Solutions/PlantesSupplements/Fiche.aspx?doc=myrrhe_ps [109] -Suty A-C « Cholestérol et phytothérapie : mythe ou réalité ? Etudes de deux plantes : le guggul et la luzerne, Thèse Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu), 1994.

T. Shen, G. Li, X. Wang, and H. Lou, The genus Commiphora: A review of its traditional uses, phytochemistry and pharmacology, Toxicity studies in mice of Commiphora molmol oleogum-resin, pp.151-154, 2001.
DOI : 10.1016/j.jep.2012.05.025

N. L. Urizar, A. B. Liverman, D. T. Dodds, F. V. Silva, P. Ordentlich et al., A Natural Product That Lowers Cholesterol As an Antagonist Ligand for FXR, Science, vol.296, issue.5573, pp.1703-1706, 2002.
DOI : 10.1126/science.1072891

E. Owsley and J. Y. Chiang, Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7??-hydroxylase gene, Biochemical and Biophysical Research Communications, vol.304, issue.1, pp.191-195, 2003.
DOI : 10.1016/S0006-291X(03)00551-5

R. W. Zink, R. J. Barr, C. D. Hepler, P. O. Szapary, M. L. Wolfe et al., « The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand » « Guggulipid for the treatment of hypercholesterolemia : a randomized controlled trial », Mol. Pharmacol. Journal of the American Medical Association, vol.67119, issue.290 6, pp.948-954, 2003.

S. Botros, S. William, F. Ebeid, D. Cioli, N. Katz et al., « Lack of evidence for an antischistosomal activity of myrrh in experimental animals », Am J Trop Med Hyg, vol.71, issue.2, pp.206-216, 2004.

A. J. Ghaith, A. Adeeb, M. H. Shallal, B. S. Hayder, and B. Sh, « The Acute Toxicity of Commiphora molmol oleo-gum-resin Methanol Extract ». Int, J. Pharm. Sci. Rev. Res, vol.33, issue.21, pp.109-114, 2015.

S. A. -masten, Department of Indian Systems of Medicine and Homeopathy, Ministry of Health and Family Welfare, Government of India, The Ayurvedic Pharmacopoeia of India Gum Guggul and Some of Its Steroidal Constituents : Review of Toxicological Literature ». US Department of Health and Human Services, National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), 2001.

G. V. Satyavati, « Gum guggul (Commiphora mukul)-the success story of an ancient insight leading to a modern discovery, Indian Journal of Medical Research, vol.87, issue.4, pp.327-335, 1988.

L. A. -nohr, L. B. Rasmussen, and J. Straand, Resin from the mukul myrrh tree, guggul, can it be used for treating hypercholesterolemia? A randomized, controlled study, Complementary Therapies in Medicine, vol.17, issue.1, pp.16-22, 2009.
DOI : 10.1016/j.ctim.2008.07.001

P. O. -szapary, M. L. Wolfe, and L. T. Bloedon, Guggulipid for the Treatment of Hypercholesterolemia, JAMA, vol.290, issue.6, pp.765-772, 2003.
DOI : 10.1001/jama.290.6.765

F. Capasso, T. S. Gaginella, and G. Grandolini, « Phytotherapy : a quick reference to Herbal Medicine, 2003.
DOI : 10.1007/978-3-642-55528-2

B. Mesrob, C. Nesbitt, R. Misra, and R. C. Pandey, High-performance liquid chromatographic method for fingerprinting and quantitative determination of E- and Z-guggulsterones in Commiphora mukul resin and its products, Journal of Chromatography B: Biomedical Sciences and Applications, vol.720, issue.1-2, pp.189-196, 1998.
DOI : 10.1016/S0378-4347(98)00433-2

S. G. Musharraf, U. Gulzar, and A. U. Rahman, Effective separation and analysis of E- and Z-guggulsterones in Commiphora mukul resin, guggulipid and their pharmaceutical product by high performance thin-layer chromatography-densitometric method, Journal of Pharmaceutical and Biomedical Analysis, vol.56, issue.2, pp.240-245, 2011.
DOI : 10.1016/j.jpba.2011.05.021