Microenvironmental regulation of metastasis, Nature Reviews Cancer, vol.19, issue.4, p.239, 2009. ,
DOI : 10.1053/sonc.2002.37263
Targeting the RAS signalling pathway in cancer]. Bull Cancer (Paris), oct, vol.98, issue.9, pp.1019-1047, 2011. ,
Mutations in Colorectal Cancer, New England Journal of Medicine, vol.369, issue.11, pp.1023-1057, 2013. ,
DOI : 10.1056/NEJMoa1305275
Mutations in Colorectal Cancer, Journal of Clinical Oncology, vol.33, issue.7, pp.692-700, 2015. ,
DOI : 10.1200/JCO.2014.59.4812
FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer, European Journal of Cancer, vol.51, issue.10, pp.1243-52, 1990. ,
DOI : 10.1016/j.ejca.2015.04.007
Mutations in Advanced Colorectal Cancer Are Associated With Poor Prognosis but Do Not Preclude Benefit From Oxaliplatin or Irinotecan: Results From the MRC FOCUS Trial, Journal of Clinical Oncology, vol.27, issue.35, pp.5931-5938, 2009. ,
DOI : 10.1200/JCO.2009.22.4295
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial, The Lancet, vol.377, issue.9783, pp.2103-2117, 2011. ,
DOI : 10.1016/S0140-6736(11)60613-2
G13D Tumor Mutations With Outcome in Patients With Metastatic Colorectal Cancer Treated With First-Line Chemotherapy With or Without Cetuximab, Journal of Clinical Oncology, vol.30, issue.29, pp.3570-3577, 2012. ,
DOI : 10.1200/JCO.2012.42.2592
BRAF-Directed Therapy in Metastatic Colorectal Cancer, The Cancer Journal, vol.22, issue.3, pp.175-183, 2016. ,
DOI : 10.1097/PPO.0000000000000189
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922502/pdf
The BRAF mutation is associated with the prognosis in colorectal cancer, Journal of Cancer Research and Clinical Oncology, vol.127, issue.2, pp.1863-71, 2014. ,
DOI : 10.3748/wjg.v13.i28.3784
FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study, The Lancet Oncology, vol.16, issue.13, pp.1306-1321, 2015. ,
DOI : 10.1016/S1470-2045(15)00122-9
Natural history of hepatic metastases from colorectal cancer - pathobiological pathways with clinical significance, World Journal of Gastroenterology, vol.20, issue.14, pp.3719-3756, 2014. ,
DOI : 10.3748/wjg.v20.i14.3719
Bevacizumab in Combination With Fluorouracil and Leucovorin: An Active Regimen for First-Line Metastatic Colorectal Cancer, Journal of Clinical Oncology, vol.23, issue.15, pp.3502-3510, 2005. ,
DOI : 10.1200/JCO.2005.10.017
Managing synchronous liver metastases from colorectal cancer: A multidisciplinary international consensus, Cancer Treatment Reviews, vol.41, issue.9, pp.729-741, 2015. ,
DOI : 10.1016/j.ctrv.2015.06.006
URL : http://www.cancertreatmentreviews.com/article/S0305737215001280/pdf
ESMO consensus guidelines for the management of patients with metastatic colorectal cancer, Annals of Oncology, vol.27, issue.8, pp.1386-422, 2016. ,
DOI : 10.1093/annonc/mdw235
Surgical Therapy for Colorectal Metastases to the Liver, Journal of Gastrointestinal Surgery, vol.22, issue.Suppl 4, pp.1057-77, 2007. ,
DOI : 10.1200/JCO.2004.06.114
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial, The Lancet Oncology, vol.14, issue.12, pp.1208-1223, 2013. ,
DOI : 10.1016/S1470-2045(13)70447-9
Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial, The Lancet, vol.371, issue.9617, pp.1007-1023, 2008. ,
DOI : 10.1016/S0140-6736(08)60455-9
The Role of Biological Agents in the Resection of Colorectal Liver Metastases, Clinical Oncology, vol.24, issue.6, pp.432-474, 2012. ,
DOI : 10.1016/j.clon.2012.01.002
Toward optimized front-line therapeutic strategies in patients with metastatic colorectal cancer--an expert review from the International Congress on Anti-Cancer Treatment (ICACT) 2009, Annals of Oncology, vol.21, issue.8, pp.1579-84, 2009. ,
DOI : 10.1093/annonc/mdq043
URL : https://hal.archives-ouvertes.fr/hal-00741712
A Randomized Phase II Trial of Three Intensified Chemotherapy Regimens in First-Line Treatment of Colorectal Cancer Patients with Initially Unresectable or Not Optimally Resectable Liver Metastases. The METHEP Trial, Annals of Surgical Oncology, vol.16, issue.13, pp.4289-97, 2013. ,
DOI : 10.1634/theoncologist.2011-0141
Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy, Transactions of the ... Meeting of the American Surgical Association, vol.CXXII, issue.&NA;, pp.644-657, 2004. ,
DOI : 10.1097/01.sla.0000141198.92114.f6
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356466/pdf
Complete Response of Colorectal Liver Metastases After Chemotherapy: Does It Mean Cure?, Journal of Clinical Oncology, vol.24, issue.24, pp.3939-3984, 2006. ,
DOI : 10.1200/JCO.2006.05.8727
Dangerous halo after neoadjuvant chemotherapy and two-step hepatectomy for colorectal liver metastases, British Journal of Surgery, vol.34, issue.1, pp.95-103, 2009. ,
DOI : 10.1016/j.ejso.2007.09.016
Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer, New England Journal of Medicine, vol.360, issue.14, pp.1408-1425, 2009. ,
DOI : 10.1056/NEJMoa0805019
Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer, Journal of Clinical Oncology, vol.27, issue.5, pp.663-71, 2009. ,
DOI : 10.1200/JCO.2008.20.8397
Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study)???, Annals of Oncology, vol.25, issue.5, pp.1018-1043, 2014. ,
DOI : 10.1093/annonc/mdu088
Bevacizumab plus mFOLFOX-6 or FOLFOXIRI in patients with initially unresectable liver metastases from colorectal cancer: the OLIVIA multinational randomised phase II trial, Annals of Oncology, vol.26, issue.4, pp.702-710, 2015. ,
DOI : 10.1093/annonc/mdu580
Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liverlimited metastases, J Clin Oncol Off J Am Soc Clin Oncol. 1 juin, vol.31, issue.16, 2013. ,
A multicentre study of capecitabine, oxaliplatin plus bevacizumab as perioperative treatment of patients with poor-risk colorectal liver-only metastases not selected for upfront resection, Annals of Oncology, vol.22, issue.9, pp.2042-2050, 2011. ,
DOI : 10.1093/annonc/mdq714
Pathologic Response to Preoperative Chemotherapy: A New Outcome End Point After Resection of Hepatic Colorectal Metastases, Journal of Clinical Oncology, vol.26, issue.33, pp.5344-51, 2008. ,
DOI : 10.1200/JCO.2008.17.5299
Patients With Initially Unresectable Colorectal Liver Metastases: Is There a Possibility of Cure?, Journal of Clinical Oncology, vol.27, issue.11, pp.1829-1864, 2009. ,
DOI : 10.1200/JCO.2008.19.9273
Complete Pathologic Response After Preoperative Chemotherapy for Colorectal Liver Metastases: Myth or Reality?, Journal of Clinical Oncology, vol.26, issue.10, pp.1635-1676, 2008. ,
DOI : 10.1200/JCO.2007.13.7471
The Role of Preoperative Chemotherapy in Patients with Resectable Colorectal Liver Metastases, Annals of Surgical Oncology, vol.23, issue.18S, pp.2385-90, 2009. ,
DOI : 10.1038/bjc.1998.333
Patients Operated On for Initially Unresectable Colorectal Liver Metastases With Missing Metastases Experience a Favorable Long-Term Outcome, Annals of Surgery, vol.254, issue.1, pp.114-122, 2011. ,
DOI : 10.1097/SLA.0b013e31821ad704
Complete Radiological Response of Colorectal Liver Metastases after Chemotherapy: What Can We Expect?, Digestive Surgery, vol.28, issue.2, pp.114-134, 2011. ,
DOI : 10.1159/000323820
Predictors of a true complete response among disappearing liver metastases from colorectal cancer after chemotherapy, Cancer, vol.16, issue.6, pp.1502-1511, 2010. ,
DOI : 10.1002/cncr.24912
Importance of Complete Pathologic Response to Prehepatectomy Chemotherapy in Treating Colorectal Cancer Metastases, Annals of Surgery, vol.250, issue.6 ,
DOI : 10.1097/SLA.0b013e3181b0c6e4
Outcome of Posthepatectomy-Missing Colorectal Liver Metastases after Complete Response to Chemotherapy: Impact of Adjuvant Intra-arterial Hepatic Oxaliplatin, Annals of Surgical Oncology, vol.24, issue.1, pp.3188-94, 2007. ,
DOI : 10.1245/s10434-007-9482-9
Is Hepatic Resection Justified After Chemotherapy in Patients With Colorectal Liver Metastases and Lymph Node Involvement?, Journal of Clinical Oncology, vol.26, issue.22, pp.3672-80, 2008. ,
DOI : 10.1200/JCO.2007.15.7297
Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery, Annals of Oncology, vol.18, issue.2, pp.299-304, 2007. ,
DOI : 10.1093/annonc/mdl386
Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases, Journal of Clinical Oncology, vol.24, issue.13, pp.2065-72, 2006. ,
DOI : 10.1200/JCO.2005.05.3074
Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin-based chemotherapy for colorectal liver metastases, Cancer, vol.27, issue.12, pp.2761-2768, 2007. ,
DOI : 10.1038/sj.bmt.1703061
Hepatic complications following preoperative chemotherapy with oxaliplatin or irinotecan for hepatic colorectal metastases, European Journal of Surgical Oncology (EJSO), vol.34, issue.6, pp.609-623, 2008. ,
DOI : 10.1016/j.ejso.2007.07.007
Predicting High Grade Lesions of Sinusoidal Obstruction Syndrome Related to Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases, Annals of Surgery, vol.251, issue.3, pp.454-60, 2010. ,
DOI : 10.1097/SLA.0b013e3181c79403
Surgically Staged Focal Liver Lesions: Accuracy and Reproducibility of Dual-Phase Helical CT for Detection and Characterization, Radiology, vol.227, issue.3, pp.752-759, 2003. ,
DOI : 10.1148/radiol.2273011768
Comparison of MR and PET imaging for the evaluation of liver metastases, Journal of Magnetic Resonance Imaging, vol.177, issue.3, pp.343-352, 2003. ,
DOI : 10.1002/jmri.10265
The impact of fluor-18-deoxyglucose-positron emission tomography in the management of colorectal liver metastases, Cancer, vol.233, issue.12, pp.2658-70, 2005. ,
DOI : 10.1097/00000658-200103000-00001
The Role and Limitations of 18-Fluoro-2-deoxy-d-glucose Positron Emission Tomography (FDG-PET) Scan and Computerized Tomography (CT) in Restaging Patients with Hepatic Colorectal Metastases Following Neoadjuvant Chemotherapy: Comparison with Operative and Pathological Findings, Journal of Gastrointestinal Surgery, vol.182, issue.Suppl 2, pp.472-480, 2007. ,
DOI : 10.2214/ajr.182.1.1820092
Improved selection of patients for hepatic surgery of colorectal liver metastases with (18)F-FDG PET: a randomized study, J Nucl Med Off Publ Soc Nucl Med. juill, vol.50, issue.7, pp.1036-1077, 2009. ,
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1), European Journal of Cancer, vol.45, issue.2, pp.228-275, 1990. ,
DOI : 10.1016/j.ejca.2008.10.026
Association of Computed Tomography Morphologic Criteria With Pathologic Response and Survival in Patients Treated With Bevacizumab for Colorectal Liver Metastases, JAMA, vol.302, issue.21, pp.2338-2382, 2009. ,
DOI : 10.1001/jama.2009.1755
Additional value of contrast enhanced intraoperative ultrasound for colorectal liver metastases, European Journal of Radiology, vol.67, issue.1, pp.169-76, 2008. ,
DOI : 10.1016/j.ejrad.2007.03.017
Potential Value of Contrast-Enhanced Intraoperative Ultrasonography During Partial Hepatectomy for Metastases, Annals of Surgery, vol.243, issue.2, pp.236-276, 2006. ,
DOI : 10.1097/01.sla.0000197708.77063.07
[Surgical treatment of liver metastasis in patients with colorectal cancer]. Presse Medicale Paris Fr 1983, janv, vol.41, issue.1, pp.58-67, 2012. ,
Clinical Score for Predicting Recurrence After Hepatic Resection for Metastatic Colorectal Cancer, Annals of Surgery, vol.230, issue.3, pp.309-318, 1999. ,
DOI : 10.1097/00000658-199909000-00004
R1 Resection by Necessity for Colorectal Liver Metastases, Transactions of the ... Meeting of the American Surgical Association, vol.126, pp.269-80, 2008. ,
DOI : 10.1097/SLA.0b013e31818a07f1
Remnant Liver Volume to Body Weight Ratio ???0.5%: A New Cut-Off to Estimate Postoperative Risks after Extended Resection in Noncirrhotic Liver, Journal of the American College of Surgeons, vol.204, issue.1, pp.22-33, 2007. ,
DOI : 10.1016/j.jamcollsurg.2006.09.007
Survival benefit of repeat liver resections for recurrent colorectal metastases: 143 cases. Association Francaise de Chirurgie., Journal of Clinical Oncology, vol.12, issue.7, pp.1491-1497, 1994. ,
DOI : 10.1200/JCO.1994.12.7.1491
Importance of Response to Neoadjuvant Chemotherapy in Patients Undergoing Resection of Synchronous Colorectal Liver Metastases, Journal of Gastrointestinal Surgery, vol.7, issue.1, pp.109-115, 2003. ,
DOI : 10.1016/S1091-255X(02)00121-X
Neoadjuvant chemotherapy and resection of advanced synchronous liver metastases before treatment of the colorectal primary, British Journal of Surgery, vol.231, issue.7, pp.872-880, 2006. ,
DOI : 10.1002/bjs.5346
Prise en charge des patients atteints de m??tastases h??patiques synchrones du cancer colorectal. Recommandations pour la Pratique Clinique. Recommandations de la Soci??t?? fran??aise de chirurgie digestive (SFCD) et de l???association de chirurgie hepatobiliaire et de transplantation h??patique (ACHBT). Texte court, Journal de Chirurgie Visc??rale, vol.148, issue.3, pp.196-208, 2011. ,
DOI : 10.1016/j.jchirv.2011.05.008
A Survival Analysis of the Liver-First Reversed Management of Advanced Simultaneous Colorectal Liver Metastases, Annals of Surgery, vol.256, issue.5, pp.772-778, 2012. ,
DOI : 10.1097/SLA.0b013e3182734423
Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients: Classic, Combined or Reverse Strategy?, Journal of the American College of Surgeons, vol.210, issue.6, pp.934-975, 2010. ,
DOI : 10.1016/j.jamcollsurg.2010.02.039
Optimizing the outcome of surgery in patients with rectal cancer and synchronous liver metastases, British Journal of Surgery, vol.11, issue.3, pp.383-90, 2010. ,
DOI : 10.3748/wjg.v13.i9.1431
Surgical Management of Patients with Synchronous Colorectal Liver Metastasis: A Multicenter International Analysis, Journal of the American College of Surgeons, vol.216, issue.4, pp.707-716, 2013. ,
DOI : 10.1016/j.jamcollsurg.2012.12.029
Systematic review of surgical management of synchronous colorectal liver metastases, British Journal of Surgery, vol.15, issue.6, pp.605-617, 2014. ,
DOI : 10.1111/j.1477-2574.2012.00597.x
Synchronous colorectal liver metastasis: A network meta-analysis review comparing classical, combined, and liver-first surgical strategies, Journal of Surgical Oncology, vol.90, issue.3, pp.341-51, 2015. ,
DOI : 10.1002/bjs.4132
Two-Stage Hepatectomy: A Planned Strategy to Treat Irresectable Liver Tumors, Annals of Surgery, vol.232, issue.6, pp.777-85, 2000. ,
DOI : 10.1097/00000658-200012000-00006
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421270/pdf
Associating portal embolization and artery ligation to induce rapid liver regeneration in staged hepatectomy, British Journal of Surgery, vol.15, issue.12, pp.1541-50, 2015. ,
DOI : 10.1111/j.1477-2574.2012.00607.x
Two-stage strategy for patients with extensive bilateral colorectal liver metastases, HPB, vol.12, issue.4, pp.262-271, 2010. ,
DOI : 10.1111/j.1477-2574.2010.00161.x
URL : https://doi.org/10.1111/j.1477-2574.2010.00161.x
Two-stage hepatectomy for multiple bilobar colorectal liver metastases, British Journal of Surgery, vol.138, issue.10, pp.1463-75, 2011. ,
DOI : 10.1016/j.jss.2006.07.027
Chemotherapy Does Not Impair Hypertrophy of the Left Liver After Right Portal Vein Obstruction, Journal of Gastrointestinal Surgery, vol.10, issue.3, pp.365-70, 2006. ,
DOI : 10.1016/j.gassur.2005.09.001
Two-stage hepatectomy for multiple bilobular liver metastases from colorectal cancer, Hepatogastroenterology. juin, vol.52, issue.63, pp.913-922, 2005. ,
Right Portal Vein Ligation Combined With In Situ Splitting Induces Rapid Left Lateral Liver Lobe Hypertrophy Enabling 2-Staged Extended Right Hepatic Resection in Small-for-Size Settings, Annals of Surgery, vol.255, issue.3, pp.405-419, 2012. ,
DOI : 10.1097/SLA.0b013e31824856f5
Prediction of Mortality After ALPPS Stage-1, Annals of Surgery, vol.262, issue.5, pp.780-785, 2015. ,
DOI : 10.1097/SLA.0000000000001450
Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a??randomized EORTC Intergroup phase II study (EORTC 40004), Annals of Oncology, vol.23, issue.10, pp.2619-2645, 2012. ,
DOI : 10.1093/annonc/mds053
AJCC Cancer Staging Atlas [Internet], Disponible sur, pp.978-979, 2017. ,
Clinicopathological Features and Prognosis in Resectable Synchronous and Metachronous Colorectal Liver Metastasis, Annals of Surgical Oncology, vol.119, issue.2, pp.786-94, 2007. ,
DOI : 10.1148/radiology.218.1.r01dc1155
???Staged??? liver resection in synchronous and metachronous colorectal hepatic metastases: differences in clinicopathological features and outcome, Colorectal Disease, vol.25, issue.10Online, pp.229-235, 2010. ,
DOI : 10.1200/JCO.2007.11.0833
Prognostic impact of margin status in liver resections for colorectal metastases after bevacizumab, British Journal of Surgery, vol.302, issue.7, pp.926-961, 2017. ,
DOI : 10.1001/jama.2009.1755
Clinicopathological features and outcome in advanced colorectal cancer patients with synchronous vs metachronous metastases, British Journal of Cancer, vol.10, issue.2, pp.159-64, 2010. ,
DOI : 10.1038/sj.bjc.6604093
Survival of Patients with Synchronous and Metachronous Colorectal Liver Metastases???is there a Difference?, Journal of Gastrointestinal Surgery, vol.15, issue.Suppl 4, pp.1399-405, 2008. ,
DOI : 10.1097/01.RVI.0000159543.28222.73
The Role of Adjuvant Chemotherapy for Colorectal Liver Metastasectomy after Pre-Operative Chemotherapy: Is the Treatment Worthwhile?, Journal of Cancer, vol.8, issue.7, pp.1179-86, 2017. ,
DOI : 10.7150/jca.18091
Determinants of Long-Term Outcome in Patients Undergoing Simultaneous Resection of Synchronous Colorectal Liver Metastases, PLoS ONE, vol.20, issue.8, p.105747, 2014. ,
DOI : 10.1371/journal.pone.0105747.t003
Parenchymal-sparing Hepatectomy in Colorectal Liver Metastasis Improves Salvageability and Survival, Annals of Surgery, vol.263, issue.1, pp.146-52, 2016. ,
DOI : 10.1097/SLA.0000000000001194
Angiogenesis in Synchronous and Metachronous Colorectal Liver Metastases, Annals of Surgery, vol.255, issue.1, pp.86-94, 2012. ,
DOI : 10.1097/SLA.0b013e318238346a
The tumour biology of synchronous and metachronous colorectal liver metastases: a systematic review, Clinical & Experimental Metastasis, vol.17, issue.24, pp.457-70, 2013. ,
DOI : 10.1158/1078-0432.CCR-10-2816
Serum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasis, Cancer Epidemiology, vol.36, issue.1, pp.61-68, 2012. ,
DOI : 10.1016/j.canep.2011.05.002