Evaluation des différents paramètres selon le seuil d, p.48 ,
The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology, Best Practice & Research Clinical Obstetrics & Gynaecology, vol.18, issue.5, pp.685-706, 2004. ,
DOI : 10.1016/j.bpobgyn.2004.05.004
A meta-analysis of outcomes of conventional IVF in women with polycystic ovary syndrome, Human Reproduction Update, vol.12, issue.1, pp.13-21, 2006. ,
DOI : 10.1093/humupd/dmi036
Perspectives on Emerging Biomarkers for Non-Invasive Assessment of Embryo Viability in Assisted Reproduction, Current Molecular Medicine, vol.10, issue.2, pp.206-221, 2010. ,
DOI : 10.2174/156652410790963349
Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics, Reproductive Biology and Endocrinology, vol.7, issue.1, p.40, 2009. ,
DOI : 10.1186/1477-7827-7-40
URL : http://doi.org/10.1186/1477-7827-7-40
Role of oocyte quality in meiotic maturation and embryonic development, Reproductive Biology, vol.9, issue.3, pp.203-227, 2009. ,
DOI : 10.1016/S1642-431X(12)60027-8
URL : https://hal.archives-ouvertes.fr/inserm-00440428
Human cumulus cells as biomarkers for embryo and pregnancy outcomes, Molecular Human Reproduction, vol.16, issue.8, pp.531-539, 2010. ,
DOI : 10.1093/molehr/gaq032
URL : https://academic.oup.com/molehr/article-pdf/16/8/531/6234788/gaq032.pdf
Novel follicular fluid factors influencing oocyte developmental potential in IVF: a review, Reproductive BioMedicine Online, vol.12, issue.4, 2006. ,
DOI : 10.1016/S1472-6483(10)62005-6
Follicular fluid biomarkers for human in vitro fertilization outcome: Proof of principle 14 nov 2016 Disponible sur: http://www.ncbi.nlm.nih.gov/pmc/articles Proteomic analysis of individual human embryos to identify novel biomarkers of development and viability, Proteome Sci Fertil Steril. 1 janv, vol.1485, issue.121, pp.101-108, 2006. ,
Cell-free DNA in human follicular fluid as a biomarker of embryo quality Circulating cell free DNA: Preanalytical considerations About the possible origin and mechanism of circulating DNA):139?42. 16. Schwarzenbach H, Hoon DSB, Pantel K. Cell-free nucleic acids as biomarkers in cancer patients, Hum Reprod. 1 déc Clin Chim Acta. 23 sept Clin Chim Acta. 1 nov Nat Rev Cancer. juin Oellerich M Crit Rev Clin Lab Sci, vol.2942431311, issue.1516 3, pp.426-463, 2001. ,
Cell-free nucleic acids as non-invasive biomarkers of gynecological cancers, ovarian, endometrial and obstetric disorders and fetal aneuploidy Increased plasma cell-free DNA is associated with low pregnancy rates among women undergoing IVF?embryo transfer Mitochondrial DNA content in embryo culture medium is significantly associated with human embryo fragmentation, ):905?23. 19. Czamanski-36?41. 20. Stigliani S Cell-free DNA in Human Follicular Microenvironment: New Prognostic Biomarker to Predict in vitro Fertilization Outcomes, 2013. ,
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome, Fertil Steril. 1 janv, vol.81, issue.1, pp.19-25, 2004. ,
National Institutes of Health evidence-based methodology workshop on polycystic ovary syndrome (PCOS) NIH EbMW Rep. 2013;1?14. 24. Sirmans SM, Pate KA. Epidemiology, diagnosis, and management of polycystic ovary syndrome, Clin Epidemiol. 18 déc, vol.6, 2013. ,
Prevalence of polycystic ovaries in women with anovulation and idiopathic hursutism Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome, 671?83. 28. Hull MG. Epidemiology of infertility and polycystic ovarian disease: endocrinological and demographic studies, pp.956-27235, 1986. ,
Current perspectives of insulin resistance and polycystic ovary syndrome, 1445?54. 30. Cardozo E, Pavone ME, Hirshfeld-Cytron JE. Metabolic syndrome and oocyte quality, 2011. ,
DOI : 10.1210/jc.2003-032237
Diagnosis of polycystic ovary syndrome (PCOS): revisiting the threshold values of follicle count on ultrasound and of the serum AMH level for the definition of polycystic ovaries Development of polycystic ovary syndrome: involvement of genetic and environmental factors, 3123?9. 33. Franks S, pp.278-85, 2006. ,
Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome, ):193?205. 35. Franks S, Gharani N, McCarthy M. Candidate genes in polycystic ovary syndrome, 2006. ,
DOI : 10.1016/j.beem.2006.02.005
Hyperfunction of the Hypothalamic-Pituitary Axis in Women with Polycystic Ovarian Disease: Indirect Evidence for Partial Gonadotroph Desensitization, 405?10. 36. Waldstreicher J, pp.165-72, 1988. ,
Androgen excess is the key element in polycystic ovary syndrome Follicle dynamics and anovulation in polycystic ovary syndrome, 252?4. 38. Franks S, 2003. ,
Comparison of oocyte quality and intracytoplasmic sperm injection outcome in women with isolated polycystic ovaries or polycystic ovarian syndrome, 239?44. 41. Plachot M, 2008. ,
Oocyte and embryo quality and outcome of ICSI cycles in patients with polycystic ovary syndrome (PCOS) versus normo-ovulatory] Outcome of intracytoplasmic sperm injection in patients with polycystic ovary syndrome or isolated polycystic ovaries The outcome of in-vitro fertilization treatment in women with sonographic evidence of polycystic ovarian morphology Oocyte quality and treatment outcome in intracytoplasmic sperm injection cycles of polycystic ovarian syndrome patients, ):133?43. 43. Esinler I932?7. 44. Engmann L,167?71. 45. Ludwig M, Finas DF, pp.354-362, 1999. ,
Assisted reproduction in polycystic ovarian disease: A multicentric trial in India Is polycystic ovarian morphology related to a poor oocyte quality after controlled ovarian hyperstimulation for intracytoplasmic sperm injection? Results from a prospective, comparative study, J Hum Reprod Sci. 1 janv Fertil Steril. 1 janv, vol.6103, issue.11, pp.49-47112, 2013. ,
IVF versus ICSI in sibling oocytes from patients with polycystic ovarian syndrome: a randomized controlled trial Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the, Hum Reprod. 1 mai, vol.20105, issue.53, pp.1261-1266, 2005. ,
Oocyte quality in patients with severe ovarian hyperstimulation syndrome Oocyte quality in patients with severe ovarian hyperstimulation syndrome: A self-controlled clinical study, 1017?21. 51. Fábregues F, 1997. ,
Impact of PCOS on early embryo cleavage kinetics Unaltered timing of embryo development in women with polycystic ovarian syndrome (PCOS): a time-lapse study Fertilization and early embryology: Normal development and metabolic activity of preimplantation embryos in vitro from patients with polycystic ovaries, Fertil Steril. 1 oct Reprod Biomed Online. 1 avr J Assist Reprod Genet. juill Hum Reprod. 1 août, vol.82283210, issue.548, pp.508-522, 1995. ,
The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender Strategies for improving outcome of assisted reproduction in women with polycystic ovary syndrome: systematic review and meta-analysis Evidence-based care of recurrent miscarriage, 709?18. 57. Porter TF, Scott JR, pp.85-101, 2005. ,
Polycystic ovaries and recurrent miscarriage?a reappraisal Polycystic ovarian syndrome and the risk of spontaneous abortion following assisted reproductive technology treatment, 612?5. 59. Wang JX, Davies MJ, 2000. ,
La morphologie embryonnaire a-t-elle encore un intérêt à l'heure actuelle ? Gynécologie Obstétrique Fertil. 1 sept 2014, 661?4. 62. Wong KM, Repping S, Mastenbroek S. Limitations of Embryo Selection Methods ,
DOI : 10.1016/j.gyobfe.2014.07.036
The successful use of pronuclear embryo transfers the day following oocyte retrieval A multicenter prospective study to assess the effect of early cleavage on embryo quality, implantation, and live-birth rate Early embryo development is an indicator of implantation potential, 981?7. 65. Wharf E C. Utility of the national embryo morphology data collection by the Society for Assisted Reproductive Technologies (SART): correlation between day-3 morphology grade and live-birth outcome, pp.212-220, 1998. ,
Culture and transfer of human blastocysts Obstetric and perinatal outcomes of pregnancies conceived with embryos cultured in a time-lapse monitoring system, ):307?11. 68498?504. 69. Zollner U, Dietl J. Perinatal risks after IVF and ICSI, pp.17-22, 2011. ,
Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosomal aneuploidy screening without whole genome amplification, Fertility and Sterility, vol.105, issue.2 ,
DOI : 10.1016/j.fertnstert.2015.10.003
A non-invasive test for assessing embryo potential by gene expression profiles of human cumulus cells: a proof of concept study, 711?9. 72. Montfoort V, P.a A, Geraedts JPM, Dumoulin JCM, 2008. ,
DOI : 10.1093/molehr/gan067
Use of Both Cumulus Cells' Transcriptomic Markers and Zona Pellucida Birefringence to Select Developmentally Competent Oocytes in Human Assisted Reproductive Technologies Cumulus and granulosa cell markers of oocyte and embryo quality, 157?68. 73. ASSIDI M, pp.979-97, 2008. ,
Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer Formation of the Ovarian Follicular Antrum and Follicular Fluid Effects of in-vivo and in-vitro environments on the metabolism of the cumulus?oocyte complex and its influence on oocyte developmental capacity Proteomics of Follicular Fluid From Women With Polycystic Ovary Syndrome Suggests Molecular Defects in Follicular Development, ):535?42. 76. Rodgers RJ, Irving-Rodgers HF35?48. 78. Ambekar AS, pp.744-53, 2003. ,
Identification of overexpressed proteins by proteomic analysis using human follicular fluids derived from polycystic ovary syndrome (PCOS) patients, Fertility and Sterility, vol.88, pp.180-80, 2007. ,
DOI : 10.1016/j.fertnstert.2007.07.622
Different protein expression patterns associated with polycystic ovary syndrome in human follicular fluid during controlled ovarian hyperstimulation. Reprod Fertil Dev, pp.893-904, 2012. ,
Peptide and protein profiles in serum and follicular fluid of women undergoing IVF Oxidative stress markers in follicular fluid of women undergoing in vitro fertilization and embryo transfer Intra-follicular leptin concentration as a predictive factor for in vitro oocyte fertilization in assisted reproductive techniques The concentration of inhibin B in follicular fluid: relation to oocyte maturation and embryo development, Proteome analysis of human follicular fluid. Biochim Biophys Acta BBA -Proteins Proteomics. 1 nov High concentrations of lactoferrin in the follicular fluid correlate with embryo quality during in vitro fertilization cycles. Fertil Steril. 1 févr, pp.1724-1732, 2002. ,
Les acides nucléiques circulants et infertilité. Gynécologie Obstétrique Fertil, pp.593-601, 2015. ,
DOI : 10.1016/j.gyobfe.2015.07.016
Acides nucl??iques circulants et f??condation in vitro, 696?701. 90. Vandewoestyne M, 2014. ,
DOI : 10.1016/j.gyobfe.2014.07.014
):316?20. 91. Quinones I, Daniel B. Cell free DNA as a component of forensic evidence recovered from touched surfaces Mass spectrometric based analysis, characterization and applications of circulating cell free DNA isolated from human body fluids, Presence and potential of cell free DNA in different types of forensic samples26?30. 922?3):172?83. 93, 2011. ,
Cell-free fetal DNA in amniotic fluid supernatant for prenatal diagnosis, 14?7. 94. Costa F, 2016. ,
Pisetsky DS, Fairhurst A-M. The origin of extracellular DNA during the clearance of dead and dying cells Clinical relevance of circulating cell-free microRNAs in cancer, Seminal cell-free DNA levels measured by PicoGreen fluorochrome are associated with sperm fertility criteria111?9. 95145?56. 97. Gahan PB, Anker P, Stroun M. Metabolic DNA as the Origin of Spontaneously Released DNA? Ann N Y Acad Sci. 1 août, pp.7-17, 2007. ,
Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty):388?97. 99. Truszewska A, Foroncewicz B, P?czek L. The role and diagnostic value of cell-free DNA in systemic lupus erythematosus, Aging Cell. 1 juin Clin Exp Rheumatol, vol.1235, issue.32, pp.330-336, 2013. ,
Circulating Fetal DNA: Its Origin and Diagnostic Potential???A Review, Placenta, vol.25 ,
DOI : 10.1016/j.placenta.2004.01.005
The Role of Cell-Free Plasma DNA in Critically Ill Patients with Sepsis, Blood Purification, vol.41, issue.1-3, pp.34-40, 2016. ,
DOI : 10.1159/000440975
Cell-Free Circulating DNA: A New Biomarker for the Acute Coronary Syndrome, Cardiology, vol.7, issue.2, pp.76-84, 2013. ,
DOI : 10.1371/journal.pone.0031455
Isolation and characterization of DNA from the plasma of cancer patients, European Journal of Cancer and Clinical Oncology, vol.23, issue.6, pp.707-719, 1987. ,
DOI : 10.1016/0277-5379(87)90266-5
Increased Integrity of Free Circulating DNA in Sera of Patients with Colorectal or Periampullary Cancer: Direct Quantitative PCR for ALU Repeats, Clinical Chemistry, vol.52, issue.6, pp.1062-1071, 2006. ,
DOI : 10.1373/clinchem.2006.068577
Circulating Nucleic Acids as a Potential Source for Cancer Biomarkers, Current Molecular Medicine, vol.10, issue.2, pp.142-65, 2010. ,
DOI : 10.2174/156652410790963295
Circulating cell-free DNA in serum as a biomarker for diagnosis and prognostic prediction of colorectal cancer, British Journal of Cancer, vol.63, issue.8, pp.1482-1491, 2014. ,
DOI : 10.1158/1055-9965.EPI-05-0992
DNA Fragments in the Blood Plasma of Cancer Patients: Quantitations and Evidence for Their Origin from Apoptotic and Necrotic Cells, Cancer Res. 2 févr, vol.61, issue.4, pp.1659-65, 2001. ,
Circulating cell-free DNA: A novel biomarker for response to therapy in ovarian carcinoma, Cancer Biology & Therapy, vol.5, issue.10, pp.1369-74, 2006. ,
DOI : 10.4161/cbt.5.10.3240
Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis, Breast Cancer Research and Treatment, vol.424, issue.2, pp.163-74, 2014. ,
DOI : 10.1016/j.cca.2013.05.022
Cell-free fetal DNA in maternal blood: kinetics, source and structure, Human Reproduction Update, vol.11, issue.1, pp.59-67, 2005. ,
DOI : 10.1093/humupd/dmh053
Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies, Ultrasound in Obstetrics & Gynecology, vol.33, issue.Suppl 1, pp.530-538, 2015. ,
DOI : 10.1002/pd.4100
URL : http://onlinelibrary.wiley.com/doi/10.1002/uog.14792/pdf
Clinical application of fetal sex determination using cell-free fetal DNA in pregnant carriers of X-linked genetic disorders, Journal of Human Genetics, vol.145, issue.4, pp.296-305, 2011. ,
DOI : 10.1002/ajmg.c.30115
Effects of Aging on Ovarian Fecundity in Terms of the Incidence of Apoptotic Granulosa Cells, Journal of Assisted Reproduction and Genetics, vol.17, issue.3, pp.168-73, 2000. ,
DOI : 10.1023/A:1009422323306
Cell-free DNA induced apoptosis of granulosa cells by oxidative stress, Clinica Chimica Acta, vol.473 ,
DOI : 10.1016/j.cca.2016.11.023
Mitochondrial DNA in Day 3 embryo culture medium is a novel, non-invasive biomarker of blastocyst potential and implantation outcome, MHR: Basic science of reproductive medicine, vol.20, issue.12, pp.1238-1284, 2014. ,
DOI : 10.1093/molehr/gau086
Polycystic ovarian morphology and the diagnosis of polycystic ovary syndrome: redefining threshold levels for follicle count and serum anti-M??llerian hormone using cluster analysis, Human Reproduction, vol.32, issue.8, pp.1723-1754, 2017. ,
DOI : 10.1093/humrep/dex226
Évaluation du dosage sérique de l'hormone anti-müllérienne [Internet] Disponible sur: https://www.has-sante.fr/portail/jcms/c_2749006/fr/evaluation-du- dosage-serique-de-l-hormone-anti-mullerienne ,
Polycystic Ovary Syndrome, New England Journal of Medicine, vol.352, issue.12, pp.1223-1259, 2005. ,
DOI : 10.1056/NEJMra041536
Dose-dependent effects of gonadotropin on oocyte developmental competence and apoptosis, Reproduction, Fertility and Development, vol.23, issue.8, pp.990-996, 2011. ,
DOI : 10.1071/RD11079
High Concentration of Insulin Promotes Apoptosis of Primary Cultured Rat Ovarian Granulosa Cells Via Its Increase in Extracellular HMGB1, Reproductive Sciences, vol.205, issue.2, pp.271-278, 2015. ,
DOI : 10.1016/j.atherosclerosis.2008.12.016
The transcriptome of corona radiata cells from individual M???? oocytes that after ICSI developed to embryos selected for transfer: PCOS women compared to healthy women, Disponible sur ,
DOI : 10.1093/nar/gkq1313
mRNA expression pattern of insulin-like growth factor components of granulosa cells and cumulus cells in women with and without polycystic ovary syndrome according to oocyte maturity, Fertility and Sterility, vol.94, issue.6, pp.2417-2437, 2010. ,
DOI : 10.1016/j.fertnstert.2010.03.053
Oxidative stress and polycystic ovary syndrome: an evaluation during ovarian stimulation for intracytoplasmic sperm injection, Reproduction, vol.153, issue.1, pp.97-105, 2017. ,
DOI : 10.1530/REP-16-0084
Qualité ovocytaire et embryonnaire chez les femmes avec syndrome des ovaires polykystiques : état de l'art. Gynécologie Obstétrique Fertil Sénologie, pp.429-467, 2017. ,
DOI : 10.1016/j.gofs.2017.06.015