L. Limites, étude pourront être la taille de l'échantillon et l'absence de comparaison à d'autres groupes d'individus (groupe témoin, patients sans traitements, patients traités par AVK) 6.3. Modifications possibles du protocole avant sa mise en application

H. Autorité-de-santé-fibrillation-auriculaire-non-valvulaire, Quelle place pour les anticoagulants oraux ? [Internet]. [cité 4 janv 2017]. Disponible sur

P. Pouyanne, F. Haramburu, J. Imbs, and B. Bégaud, Admissions to hospital caused by adverse drug reactions: cross sectional incidence study, BMJ, vol.320, issue.7241, p.1036, 2000.
DOI : 10.1136/bmj.320.7241.1036

URL : http://www.bmj.com/content/bmj/320/7241/1036.full.pdf

H. Autorité-de-santé-les and «. Naco-», action directe, n'ont pas tous démontré la même efficacité [Internet]. 2015 [cité 4 janv 2017]. Disponible sur: https://www.has-sante

C. Mauprivez, R. Khonsari, O. Razouk, P. Goudot, P. Lesclous et al., Management of dental extraction in patients undergoing anticoagulant oral direct treatment: a pilot study, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol.122, issue.5, p.14655, 2016.
DOI : 10.1016/j.oooo.2016.06.003

S. Kakkos, J. Caprini, G. Geroulakos, A. Nicolaides, G. Stansby et al., Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism, Disponible sur, p.2016
DOI : 10.1002/14651858.CD005258.pub2

M. Nordström, B. Lindblad, D. Bergqvist, and T. Kjellström, A prospective study of the incidence of deep-vein thrombosis within a defined urban population, Journal of Internal Medicine, vol.1, issue.Suppl. 21, p.15560, 1992.
DOI : 10.1007/978-3-642-68863-8

F. Anderson and F. Spencer, Risk Factors for Venous Thromboembolism):I-9-I-16, Circulation. 17 juin, vol.10723, issue.1, 2003.

F. Anderson and F. Spencer, Risk Factors for Venous Thromboembolism):I-9-I-16, Circulation. 17 juin, vol.10723, issue.1, 2003.

C. Boissier, J. Magne, and C. , Référentiel de médecine vasculaire et de chirurgie vasculaire. Tours: Presses universitaire François Rabelais, 2015.

E. Messas, D. Wahl, and G. Pernod, Prise en charge de la thrombose veineuse profonde en 2015, Journal des Maladies Vasculaires, vol.41, issue.1, p.4250, 2016.
DOI : 10.1016/j.jmv.2015.07.105

C. Neurologie, E. De, M. Zuber, and L. Defebvre, Neurologie: Réussir les ECNi. 4e édition. Issy-les-Moulineaux, 2016.

T. Moulin and . Épidémiologie, ??pid??miologie, physiopathologie des accidents vasculaires c??r??braux isch??miques, Journal des Maladies Vasculaires, vol.30, p.56, 2005.
DOI : 10.1016/S0398-0499(05)74793-4

P. Niclot, I. Crassard, A. Cohen, and M. Bousser, Pr??vention des accidents vasculaires c??r??braux, EMC - Neurologie, vol.1, issue.1, 2003.
DOI : 10.1016/S0246-0378(03)00133-7

D. Lane and G. Lip, Use of the CHA2DS2-VASc and HAS-BLED Scores to Aid Decision Making for Thromboprophylaxis in Nonvalvular Atrial Fibrillation, Circulation, vol.126, issue.7, p.8605, 2012.
DOI : 10.1161/CIRCULATIONAHA.111.060061

. Thomas, Score en cardiologie, Disponible sur, p.2012, 2017.

A. Camm, G. Lip, D. Caterina, R. Savelieva, I. Atar et al., 2012 focused update of the ESC Guidelines for the management of atrial fibrillationAn update of the contribution of the European Heart Rhythm Association, Eur Heart J. 1 nov, vol.33, issue.21, p.271947, 2012.

S. Faure and J. Buxeraud, Les anticoagulants oraux directs ou AOD, Actualit??s Pharmaceutiques, vol.53, issue.541, p.110, 2014.
DOI : 10.1016/j.actpha.2014.09.018

. Vidal-eliquis, mg cp pellic -Mises en garde et précautions d'emploi [Internet]. [cité 5 sept 2017]. Disponible sur: https

. Vidal-lixiana, Mises en garde et précautions d'emploi [Internet]. [cité 5 sept 2017] Disponible sur: https://www.vidal.fr/Medicament/ lixiana_15_mg_cp_pellic-158272-mises_en_garde_et_precautions_d_emploi.htm 37. VIDAL -PRADAXA 110 mg gél -Mises en garde et précautions d'emploi [Internet], Disponible sur, 2017.

. Vidal-xarelto, 10 mg cp pellic -Mises en garde et précautions d'emploi [Internet]. [cité 5 sept 2017]. Disponible sur: https

P. Hainaut, Les Anticoagulants Oraux Directs, Mai, vol.135, issue.5, p.2538, 2016.

. Vidal-lixiana, 15 mg cp pellic -Interactions [Internet]. [cité 5 sept 2017]. Disponible sur: https

J. Mendell, H. Zahir, N. Matsushima, R. Noveck, F. Lee et al., Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor, American Journal of Cardiovascular Drugs, vol.31, issue.7???8, p.33142, 2013.
DOI : 10.1016/j.jacc.2013.02.058

D. Perrin, Manuel de chirurgie orale: technique de réalisation pratique, maîtrise et exercice raisonné au quotidien, 2012.

M. Samama, J. Conard, L. Louët, and A. , Accidents h??morragiques des nouveaux anticoagulants oraux et examens de la coagulation, Journal des Maladies Vasculaires, vol.38, issue.4, p.25970, 2013.
DOI : 10.1016/j.jmv.2013.05.005

H. Iwabuchi, Y. Imai, S. Asanami, M. Shirakawa, G. Yamane et al., Evaluation of postextraction bleeding incidence to compare patients receiving and not receiving warfarin therapy: a cross-sectional, multicentre, observational study, BMJ Open, vol.139, issue.(Suppl IV), p.5777, 2014.
DOI : 10.14219/jada.archive.2008.0251

Y. Morimoto, H. Niwa, and K. Minematsu, Risk Factors Affecting Postoperative Hemorrhage After Tooth Extraction in Patients Receiving Oral Antithrombotic Therapy, Journal of Oral and Maxillofacial Surgery, vol.69, issue.6, p.15506, 2011.
DOI : 10.1016/j.joms.2010.10.018

P. Moreira, P. Filho, E. Silva, C. Weksler, S. Drable et al., Effect of periodontal treatment on oral anticoagulation in patients with heart disease, Rev Port Cardiol Orgao Of Soc Port Cardiol Port J Cardiol Off J Port Soc Cardiol. oct, vol.26, issue.10, p.97789, 2007.

Y. Hong and S. Mun, A case of massive maxillary sinus bleeding after dental implant, International Journal of Oral and Maxillofacial Surgery, vol.40, issue.7, p.75860, 2011.
DOI : 10.1016/j.ijom.2010.11.027

S. Jensen, J. Eriksen, and M. Schiodt, Severe bleeding after sinus floor elevation using the transcrestal technique: a case report, Eur J Oral Implant, vol.5, issue.3, p.28791, 2012.

K. Panula and K. Oikarinen, Severe hemorrhage after implant surgery, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol.87, issue.1, 1999.
DOI : 10.1016/S1079-2104(99)70306-9

A. Mordenfeld, L. Andersson, and B. Bergström, Hemorrhage in the floor of the mouth during implant placement in the edentulous mandible: a case report, Int J Oral Maxillofac Implants, vol.12, issue.4, 1997.

C. Madrid, Doit-on modifier le traitement anticoagulant avant des extractions dentaires, Rev Med Suisse, vol.1, p.141824, 2005.

J. Niamtu, Near-fatal airway obstruction after routine implant placement, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol.92, issue.6, p.597600, 2001.
DOI : 10.1067/moe.2001.116503

M. Funayama, T. Kumagai, K. Saito, and T. Watanabe, Asphyxial Death Caused by Postextraction Hematoma, The American Journal of Forensic Medicine and Pathology, vol.15, issue.1, p.87, 1994.
DOI : 10.1097/00000433-199403000-00018

Y. Nizamaldin and J. Samson, Hémostase locale en Chirurgie orale. 2ème partie: efficacité de la colle de fibrine, Médecine Buccale Chir Buccale, vol.18, issue.3, 2012.
DOI : 10.1051/mbcb/2012005

C. Davis, C. Robertson, S. Shivakumar, and M. Lee, Implications of Dabigatran, a direct thrombin inhibitor, for oral surgery practice, J Can Dent Assoc, vol.79, p.74, 2013.

O. Breik, A. Cheng, P. Sambrook, and A. Goss, Protocol in managing oral surgical patients taking dabigatran, Australian Dental Journal, vol.99, issue.3, p.296301, 2014.
DOI : 10.1046/j.1365-2141.1997.4463256.x

URL : http://onlinelibrary.wiley.com/doi/10.1111/adj.12199/pdf

F. Firriolo and W. Hupp, Beyond warfarin: the new generation of oral anticoagulants and their implications for the management of dental patients. Oral Surg Oral Med Oral Pathol Oral Radiol, p.43141, 2012.

H. Fakhri, S. Janket, E. Jackson, A. Baird, R. Dinnocenzo et al., Tutorial in Oral antithrombotic therapy: Biology and dental implications, Medicina Oral Patolog??a Oral y Cirugia Bucal, vol.18, issue.3, p.46172, 2013.
DOI : 10.4317/medoral.19140

URL : http://doi.org/10.4317/medoral.19140

K. Romond, C. Miller, and R. Henry, Dental management considerations for a patient taking dabigatran etexilate: a case report, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol.116, issue.3, p.1915, 2013.
DOI : 10.1016/j.oooo.2013.05.001

P. Sié, C. Samama, A. Godier, N. Rosencher, A. Steib et al., Chirurgies et actes invasifs chez les patients traités au long cours par un anticoagulant oral anti-IIa ou anti-Xa direct. Actualisation 2012, Sang Thromb Vaiss. 1 juin, vol.24, issue.6, p.26978, 2012.

S. R. De-la, Prise en charge des patients sous traitement anti-vitamines K en chirurgie bucco-dentaire

S. Persac, F. Boland, J. Lavis, and A. Tardif, Avulsions dentaires et??anticoagulants, Revue de Stomatologie et de Chirurgie Maxillo-faciale, vol.108, issue.3, p.18992, 2007.
DOI : 10.1016/j.stomax.2006.10.007

E. Szekely, M. Baralle, R. G. Marey, A. Ferri, and J. , Avulsions dentaires et coagulophaties, Revue de Stomatologie et de Chirurgie Maxillo-faciale, vol.106, issue.5, p.27680, 2005.
DOI : 10.1016/S0035-1768(05)86041-3

S. Persac, F. Boland, J. Lavis, and A. Tardif, Avulsions dentaires et??anticoagulants, Revue de Stomatologie et de Chirurgie Maxillo-faciale, vol.108, issue.3, p.18992, 2007.
DOI : 10.1016/j.stomax.2006.10.007

A. Godier, I. Gouin-thibault, N. Rosencher, and P. Albaladejo, Gestion périopératoire des anticoagulants oraux directs, 2014.