J. Kline, J. Hernandez-nino, A. Jones, G. Rose, H. Norton et al., Prospective Study of the Clinical Features and Outcomes of Emergency Department Patients with Delayed Diagnosis of Pulmonary Embolism, Academic Emergency Medicine, vol.2, issue.7, pp.592-598, 2007.
DOI : 10.1111/j.1538-7836.2004.00795.x

P. Richman, D. Courtney, and J. Kline, Prevalence and significance of nonthromboembolic findings on chest computerized tomography angiography performed to rule-out pulmonary embolism-a multi-center study of 1025 emergency department patients

R. Smith-bindman, D. Miglioretti, and E. Johnson, Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010, JAMA, vol.307, issue.22, pp.2400-2409, 2012.
DOI : 10.1001/jama.2012.5960

C. Study and I. , Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography, JAMA, vol.295, pp.172-179, 2006.

M. Runyon, P. Richman, and J. Kline, Emergency Medicine Practitioner Knowledge and Use of Decision Rules for the Evaluation of Patients with Suspected Pulmonary Embolism: Variations by Practice Setting and Training Level, Academic Emergency Medicine, vol.129, issue.1, pp.53-57, 2007.
DOI : 10.1197/j.aem.2005.02.010

C. Jerjes-sanchez, Venous and arterial thrombosis: a continuous spectrum of the same disease?, European Heart Journal, vol.26, issue.1, pp.3-4, 2015.
DOI : 10.1093/eurheartj/ehi041

E. Vazquez-garza, C. Jerjes-sanchez, A. Navarrete, J. Joya-harrison, and D. Rodriguez, Venous thromboembolism: thrombosis, inflammation, and immunothrombosis for clinicians, Journal of Thrombosis and Thrombolysis, vol.56, issue.Suppl 1, pp.1-9, 2017.
DOI : 10.1016/j.jacc.2010.04.063

B. Furie, Mechanisms of Thrombus Formation, New England Journal of Medicine, vol.359, issue.9, pp.938-949, 2008.
DOI : 10.1056/NEJMra0801082

C. Jerjes-sanchez, Mechanisms of thrombosis. Thrombolysis pulm, Embolism, pp.1-17, 2015.

D. Corrigan, C. Prucnal, and C. Kabrhel, Pulmonary embolism: the diagnosis, riskstratification , treatment and disposition of emergency department patients, Sept, vol.3, issue.3, pp.117-125, 2016.

S. Konstantinides, A. Torbicki, G. Agnelli, N. Danchin, and D. Fitzmaurice, 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism, European Heart Journal, vol.35, pp.3033-3080, 2014.

S. Bouée, C. Emery, A. Samson, J. Gourmelen, C. Bailly et al., Incidence of venous thromboembolism in France: a retrospective analysis of a national insurance claims database, Thrombosis Journal, vol.16, issue.Suppl A, 2016.
DOI : 10.1093/eurheartj/sut013

J. Kline and C. Kabrhel, Emergency Evaluation for Pulmonary Embolism, Part 1: Clinical Factors that Increase Risk, The Journal of Emergency Medicine, vol.48, issue.6, pp.771-780, 2015.
DOI : 10.1016/j.jemermed.2014.12.040

S. Goldhaber and H. Bounameaux, Pulmonary embolism and deep vein thrombosis, The Lancet, vol.379, issue.9828, pp.1835-1846, 2012.
DOI : 10.1016/S0140-6736(11)61904-1

C. Pollack, D. Schreiber, and S. Goldhaber, Clinical Characteristics, Management, and Outcomes of Patients Diagnosed With Acute Pulmonary Embolism in the Emergency Department, Journal of the American College of Cardiology, vol.57, issue.6, pp.700-706, 2011.
DOI : 10.1016/j.jacc.2010.05.071

L. Guérin, F. Couturaud, F. Parent, M. Revel, F. Gillaizeau et al., Prevalence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism, Thrombosis and Haemostasis, vol.112, issue.3
DOI : 10.1160/TH13-07-0538

K. Ginsburg, M. Liang, L. Newcomer, S. Goldhaber, and P. Schur, Anticardiolipin antibodies and the risk of ischemic stroke and venous thrombosis, pp.997-1002, 1992.

P. Stein, A. Beemath, F. Meyers, E. Skaf, J. Sanchez et al., Incidence of Venous Thromboembolism in Patients Hospitalized with Cancer, The American Journal of Medicine, vol.119, issue.1, pp.60-68, 2006.
DOI : 10.1016/j.amjmed.2005.06.058

J. Kline, Diagnosis and exclusion of pulmonary embolism. Thrombosis Research, 2017.

S. Konstantinides and A. Torbicki, Management of pulmonary embolism: recent evidence and the new European guidelines: Figure 1???, European Respiratory Journal, vol.44, issue.6, pp.1385-1390, 2014.
DOI : 10.1183/09031936.00180414

H. Robert-ebadi and M. Righini, Diagnostic de l???embolie pulmonaire, Revue des Maladies Respiratoires, vol.28, issue.6, pp.790-799, 2011.
DOI : 10.1016/j.rmr.2010.10.039

J. Shen, H. Chen, J. Chen, J. Xing, P. Gu et al., Comparison of the Wells score with the revised Geneva score for assessing suspected pulmonary embolism: a systematic review and meta-analysis, Journal of Thrombosis and Thrombolysis, vol.16, issue.1, pp.482-492, 2016.
DOI : 10.1097/MEJ.0b013e328304ae6d

C. Calisir, U. Yavas, I. Ozkan, F. Alatas, A. Cevik et al., Performance of the Wells and Revised Geneva scores for predicting pulmonary embolism, European Journal of Emergency Medicine, vol.16, issue.1, pp.49-52, 2009.
DOI : 10.1097/MEJ.0b013e328304ae6d

B. Singh, S. Mommer, P. Erwin, S. Mascarenhas, and A. Parsaik, Pulmonary embolism rule-out criteria (PERC) in pulmonary embolism???revisited: A systematic review and meta-analysis, Emergency Medicine Journal, vol.17, issue.9
DOI : 10.1111/j.1553-2712.2010.00826.x

D. Jimenez, D. Kopecna, V. Tapson, B. Briese, D. Schreiber et al., Derivation and Validation of Multimarker Prognostication for Normotensive Patients with Acute Symptomatic Pulmonary Embolism, American Journal of Respiratory and Critical Care Medicine, vol.189, issue.6, pp.718-726, 2014.
DOI : 10.1164/rccm.201311-2040OC

I. Mos, F. Klok, L. Kroft, O. Dekkers, and M. Huisman, Safety of ruling out acute pulmonary embolism by normal computed tomography pulmonary angiography in patients with an indication for computed tomography: systematic review and meta-analysis, Journal of Thrombosis and Haemostasis, vol.56, issue.9
DOI : 10.1164/ajrccm.159.1.9803109

I. Mos, F. Klok, L. Kroft, O. Dekkers, and M. Huisman, Safety of ruling out acute pulmonary embolism by normal computed tomography pulmonary angiography in patients with an indication for computed tomography: systematic review and meta-analysis, Journal of Thrombosis and Haemostasis, vol.56, issue.9
DOI : 10.1164/ajrccm.159.1.9803109

D. Courtney, C. Miller, H. Smithline, N. Klekowski, M. Hogg et al., Prospective multicenter assessment of interobserver agreement for radiologist interpretation of multidetector computerized tomographic angiography for pulmonary embolism, Journal of Thrombosis and Haemostasis, vol.135, issue.3, pp.533-540, 2010.
DOI : 10.7326/0003-4819-135-2-200107170-00008

L. Moores, J. Kline, A. Portillo, S. Resano, A. Vicente et al., Multidetector computed tomographic pulmonary angiography in patients with a high clinical probability of pulmonary embolism, Journal of Thrombosis and Haemostasis, vol.354, issue.1, pp.114-120, 2016.
DOI : 10.1056/NEJMe068076

A. Schissler, A. Rozenshtein, M. Kulon, G. Pearson, R. Green et al., CT Pulmonary Angiography: Increasingly Diagnosing Less Severe Pulmonary Emboli, PLoS ONE, vol.187, issue.1, 2013.
DOI : 10.1371/journal.pone.0065669.t004

D. Adams, S. Stevens, S. Woller, R. Evans, J. Lloyd et al., Adherence to PIOPED II Investigators' Recommendations for Computed Tomography Pulmonary Angiography, The American Journal of Medicine, vol.126, issue.1, pp.36-42, 2013.
DOI : 10.1016/j.amjmed.2012.05.028

D. Exter, P. Van-roosmalen, M. Van-den-hoven, P. Klok, F. Monreal et al., Physicians' management approach to incidental pulmonary embolism: an international survey, J. Thromb. Haemost, 2012.

R. Pesavento, F. Casazza, L. Filippi, M. Milan, M. Monreal et al., An international survey on isolated subsegmental pulmonary embolism, Thrombosis Research, vol.131, issue.2, pp.183-184, 2013.
DOI : 10.1016/j.thromres.2012.11.017

A. Einstein, M. Henzlova, and S. Rajagopalan, Estimating Risk of Cancer Associated With Radiation Exposure From 64-Slice Computed Tomography Coronary Angiography, JAMA, vol.298, issue.3, pp.317-323
DOI : 10.1001/jama.298.3.317

J. Mcdonald, R. Mcdonald, and J. Comin, Frequency of Acute Kidney Injury Following Intravenous Contrast Medium Administration: A Systematic Review and Meta-Analysis, Radiology, vol.267, issue.1
DOI : 10.1148/radiol.12121460

J. Phillips, J. Straiton, and R. Staff, Planar and SPECT ventilation/perfusion imaging and computed tomography for the diagnosis of pulmonary embolism: A systematic review and meta-analysis of the literature, and cost and dose comparison, European Journal of Radiology, vol.84, issue.7, pp.1392-1400, 2015.
DOI : 10.1016/j.ejrad.2015.03.013

J. Reid, E. Coche, T. Inoue, E. Kim, M. Dondi et al., Is the lung scan alive and well? Facts and controversies in defining the role of lung scintigraphy for the diagnosis of pulmonary embolism in the era of MDCT, European Journal of Nuclear Medicine and Molecular Imaging, vol.333, issue.7590, pp.505-521, 2009.
DOI : 10.1148/radiology.166.2.3122266

R. Hull, J. Hirsh, C. Carter, R. Jay, P. Dodd et al., Pulmonary Angiography, Ventilation Lung Scanning, and Venography for Clinically Suspected Pulmonary Embolism with Abnormal Perfusion Lung Scan, Annals of Internal Medicine, vol.98, issue.6, pp.891-899, 1983.
DOI : 10.7326/0003-4819-98-6-891

J. Kline, Diagnosis and Exclusion of Pulmonary Embolism. Thrombosis Research, 2017.

R. Wiener, L. Schwartz, and S. Woloshin, Time Trends in Pulmonary Embolism in the United States, Archives of Internal Medicine, vol.171, issue.9, pp.831-838, 2011.
DOI : 10.1001/archinternmed.2011.178

A. Perrier, P. Roy, D. Aujesky, I. Chagnon, N. Howarth et al., Diagnosing pulmonary embolism in outpatients with clinical assessment, D-Dimer measurement, venous ultrasound, and helical computed tomography: a multicenter management study, The American Journal of Medicine, vol.116, issue.5, pp.291-299, 2004.
DOI : 10.1016/j.amjmed.2003.09.041

F. Klok, E. Kruisman, and J. Spaan, Comparison of the revised Geneva score with the Wells rule for assessing clinical probability of pulmonary embolism, Journal of Thrombosis and Haemostasis, vol.5, issue.1, pp.40-44, 2008.
DOI : 10.1148/radiology.143.1.7063747

URL : https://hal.archives-ouvertes.fr/hal-00684119

E. Ceriani, C. Combescure, G. Gal, M. Nendaz, T. Perneger et al., Clinical prediction rules for pulmonary embolism: a systematic review and meta-analysis. journal of thrombosis and haemostasis, pp.957-970, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00678591

W. Lucassen, G. Geersing, P. Erkens, J. Reitsma, K. Moons et al., Clinical Decision Rules for Excluding Pulmonary Embolism: A Meta-analysis, Annals of Internal Medicine, vol.155, issue.7, pp.448-60, 2011.
DOI : 10.7326/0003-4819-155-7-201110040-00007

M. Pepe, H. Janes, and G. Longton, Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic, Prognostic, or Screening Marker, American Journal of Epidemiology, vol.159, issue.9, pp.882-890, 2004.
DOI : 10.1093/aje/kwh101

A. Penaloza, C. Melot, and S. Motte, Comparison of the Wells score with the simplified revised Geneva score for assessing pretest probability of pulmonary embolism, Thrombosis Research, vol.127, issue.2, pp.81-84, 2011.
DOI : 10.1016/j.thromres.2010.10.026

I. Chagnon, H. Bounameaux, D. Aujesky, P. Roy, A. Gourdier et al., Comparison of two clinical prediction rules and implicit assessment among patients with suspected pulmonary embolism, The American Journal of Medicine, vol.113, issue.4, pp.269-275, 2002.
DOI : 10.1016/S0002-9343(02)01212-3

C. Kabrhel, A. Mcafee, and S. Goldhaber, The Contribution of the Subjective Component of the Canadian Pulmonary Embolism Score to the Overall Score in Emergency Department Patients, Academic Emergency Medicine, vol.83, issue.10, pp.915-920, 2005.
DOI : 10.1001/archinte.161.1.92

P. Roy, G. Meyer, B. Vielle, L. Gall, C. Verschuren et al., Appropriateness of Diagnostic Management and Outcomes of Suspected Pulmonary Embolism, Annals of Internal Medicine, vol.144, issue.3, pp.157-64, 2006.
DOI : 10.7326/0003-4819-144-3-200602070-00003

D. Musset, F. Parent, G. Meyer, S. Maitre, P. Girard et al., Diagnostic strategy for patients with suspected pulmonary embolism: a prospective multicentre outcome study, The Lancet, vol.360, issue.9349, pp.1914-1934, 2002.
DOI : 10.1016/S0140-6736(02)11914-3

URL : https://hal.archives-ouvertes.fr/hal-00722286

A. Penaloza, F. Verschuren, G. Meyer, S. Quentin-georget, C. Soulie et al., Comparison of the Unstructured Clinician Gestalt, the Wells Score, and the Revised Geneva Score to Estimate Pretest Probability for Suspected Pulmonary Embolism, Annals of Emergency Medicine, vol.62, issue.2, pp.117-124, 2013.
DOI : 10.1016/j.annemergmed.2012.11.002

A. Venkatesh, J. Kline, D. Courtney, C. Camargo, M. Plewa et al., Evaluation of Pulmonary Embolism in the Emergency Department and Consistency With a National Quality Measure, Archives of Internal Medicine, vol.172, issue.13, pp.1028-1032, 2012.
DOI : 10.1001/archinternmed.2012.1804

M. Perera, L. Aggarwal, I. Scott, and N. Cocks, Underuse of risk assessment and overuse of CTPA in patients with suspected pulmonary thromboembolism, Intern Med J, 2017.

A. Perelas, A. Dimou, A. Saenz, J. Rhee, K. Teerapuncharoen et al., CT Pulmonary Angiography Utilization in the Emergency Department, American Journal of Medical Quality, vol.13, issue.4, pp.571-577, 2015.
DOI : 10.1056/NEJMra072149

W. Hall, S. Truitt, and L. Scheunemann, The Prevalence of Clinically Relevant Incidental Findings on Chest Computed Tomographic Angiograms Ordered to Diagnose Pulmonary Embolism, Archives of Internal Medicine, vol.169, issue.21, pp.1961-1965, 2009.
DOI : 10.1001/archinternmed.2009.360

C. Ong, V. Malipatil, M. Lavercombe, K. Teo, P. Coughlin et al., Implementation of a clinical prediction tool for pulmonary embolism diagnosis in a tertiary teaching hospital reduces the number of computed tomography pulmonary angiograms performed, Internal Medicine Journal, vol.184, issue.2, pp.169-174, 2013.
DOI : 10.2214/ajr.184.2.01840623

Y. Freund, A. Rousseau, F. Guyot-rousseau, Y. Claessens, O. Hugli et al., PERC rule to exclude the diagnosis of pulmonary embolism in emergency lowrisk patients: study protocol for the PROPER randomized controlled study, Trials, vol.16, issue.537, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01260461