Bilan du dépistage par télémédecine de la rétinopathie du prématuré dans une maternité de niveau 3 en France sur une période de 6 ans

Abstract : Purpose: to analyze the prevalence and risk factors of retinopathy of prematurity (ROP) and of treatment-requiring ROP. Methods: a retrospective study was conducted in a level III neonatal unit in Bordeaux, France, during 2009-2015. 419 preterm infants whose ROP was screened for ROP exclusively with RetCam were included. Results: ROP of any degree was diagnosed in 27.68% of infants. Stage 1, 2, 3 and 4 ROP was found in 44%, 46%, 9% and 1% of subjects, respectively. No fifth stage of ROP was observed. 28/419 (6,6 %) infants were treated by exclusive laser photocoagulation. No intravitreal anti-VEGF injections or surgical treatments were performed. No infant born at>31 weeks or with BW>1110g needed ROP treatment. In multivariate analysis, risk factors for ROP development were low birth weight, low gestational age at birth, high total days of invasive mechanical ventilation and shock or vasoactive substances use. In multivariate analysis, risk factors for treatment-severe ROP were male gender, gestational age 27 weeks and Apgar score at 5 minutes 7. Conclusion: in our 6-year series, ROP was successfully screened by exclusive telemedecine and no surgical treatment was required. This study identifies known ROP risk factors but Apgar score at 5 minutes as severe ROP risk factor requires furthers studies in order to be confirmed.
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Master Thesis
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Hélène Chan. Bilan du dépistage par télémédecine de la rétinopathie du prématuré dans une maternité de niveau 3 en France sur une période de 6 ans. Médecine humaine et pathologie. 2017. ⟨dumas-01628358⟩

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