P. Patel, Estimating per-act HIV transmission risk, AIDS, vol.28, issue.10
DOI : 10.1097/QAD.0000000000000298

URL : http://pdfs.journals.lww.com/aidsonline/2014/06190/Estimating_per_act_HIV_transmission_risk___a.14.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1504645383006;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21Csk0OpQi3YbjEMdSoz2UhVybFqQxA7lKwSUlA502zQZr96TQRwhVlocEp/sJ586aVbcBFlltKNKo+tbuMfL73hiPqJliudqs17cHeLcLbV/CqjlP3IO0jGHlHQtJWcICDdAyGJMnpi6RlbEJaRheGeh5z5uvqz3FLHgPKVXJzdN2ziiHhY6wPF9tfA80junp3gbCN2dwu4iY3GgI1hDvc=;hash|BzuQmmfGWh49HM+9tjjqcw==

M. Stevenson and «. Hiv, HIV-1 pathogenesis, Nature Medicine, vol.9, issue.7, pp.853-60, 2003.
DOI : 10.1038/nm0703-853

E. Mylonakis, M. Paliou, and J. D. Rich, « Plasma Viral Load Testing in the Management of HIV Infection, American Family Physician, vol.63, issue.3, pp.483-90, 2001.

. Tsao, CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo, Retrovirology, vol.233, issue.80, p.22, 2016.
DOI : 10.1006/viro.1997.8606

G. Martrus and M. Altfeld, Immunological Strategies to Target HIV Persistence doi:10.1097/COH.0000000000000289. 6 « 1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS among Adolescents and Adults, Current Opinion in HIV and AIDS MMWR. Recommendations and Reports: Morbidity and Mortality Weekly Report. Recommendations and Reports Centers for Disease Control, vol.41, pp.17-18, 1992.
DOI : 10.1097/coh.0000000000000289

K. Deng, Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations, Nature, vol.304, issue.7534, pp.7534-381, 2015.
DOI : 10.1038/nprot.2009.7

P. Brugnaro, Non-AIDS definings malignancies among human immunodeficiency virus-positive subjects: Epidemiology and outcome after two decades of HAART era, World Journal of Virology, vol.4, issue.3, pp.209-227
DOI : 10.5501/wjv.v4.i3.209

P. Vishnu and M. David, Haematological manifestations of human immune deficiency virus infection, British Journal of Haematology, vol.25, issue.5, pp.695-709, 2015.
DOI : 10.1172/JCI67225

URL : http://onlinelibrary.wiley.com/doi/10.1111/bjh.13783/pdf

T. Nadia, K. L. Sebastian, . Collins, H. Targeting, and . Latency, Resting Memory T Cells, Hematopoietic Progenitor Cells and Future Directions, Expert Review of Anti- Infective Therapy, vol.12, pp.10-1187, 2014.

D. Mildvan, Prevalence of anemia and correlation with biomarkers and specific antiretroviral regimens in 9690 human immunodeficiency virus-infected patients: findings of the Anemia Prevalence Study, Current Medical Research and Opinion, vol.23, issue.2, pp.343-55, 2007.
DOI : 10.1185/030079906X162683

K. Koefoed and H. J. Ditzel, « Identification of Talin Head Domain as an Immunodominant Epitope of the Antiplatelet Antibody Response in Patients with

J. E. Groopman, Zidovudine Intolerance, Clinical Infectious Diseases, vol.12, issue.Supplement_5, pp.500-506, 1990.
DOI : 10.1093/clinids/12.Supplement_5.S500

K. Takahashi, Clinical and cytogenetic characteristics of myelodysplastic syndrome in patients with HIV infection, Leukemia Research, vol.36, issue.11, pp.1376-79, 2012.
DOI : 10.1016/j.leukres.2012.08.003

A. Daniel and . Arber, « The 2016 Revision to the World Health Organization (WHO) Classification of Myeloid Neoplasms and Acute Leukemia, Blood, pp.10-1182, 2016.

A. H. Shih, The role of mutations in epigenetic regulators in myeloid malignancies, Nature Reviews Cancer, vol.82, issue.9, pp.599-612, 2012.
DOI : 10.1200/JCO.2002.09.088

J. S. Welch, The Origin and Evolution of Mutations in Acute Myeloid Leukemia, Cell, vol.150, issue.2, 2012.
DOI : 10.1016/j.cell.2012.06.023

L. Ding, « Clonal Evolution in Relapsed Acute Myeloid Leukaemia Revealed by Whole-Genome Sequencing », Nature 481, 506?10. 26 E. Estey et al., « Prediction of Survival during Induction Therapy in Patients with Newly Diagnosed Acute Myeloblastic Leukemia, pp.7382-257, 1989.
DOI : 10.1038/nature10738

URL : http://www.nature.com/nature/journal/v481/n7382/pdf/nature10738.pdf

J. Menzin, The Outcomes and Costs of Acute Myeloid Leukemia Among the Elderly, 1597?1603. 28 G. Leone et al. The Incidence of Secondary Leukemias, pp.10-937, 1999.
DOI : 10.1001/archinte.162.14.1597

R. F. Schlenk, Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia, New England Journal of Medicine, vol.358, issue.18, 2008.
DOI : 10.1056/NEJMoa074306

K. Mrózek, Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia, Journal of Clinical Oncology, vol.30, issue.36, pp.36-4515, 2012.
DOI : 10.1200/JCO.2012.43.4738

P. Jay, R. L. Patel, and . Levine, « How Do Novel Molecular Genetic Markers Influence Treatment Decisions in Acute Myeloid Leukemia? », Hematology / the Education Program of the, Education Program, pp.2012-2040, 2012.

H. Döhner, Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet, Blood, vol.115, issue.3, pp.453-74
DOI : 10.1182/blood-2009-07-235358

A. K. Burnett, The treatment of AML: Current status and novel approaches, Hematology, vol.104, issue.sup1, pp.50-53, 2005.
DOI : 10.1182/blood-2003-03-0925

T. Büchner, ACUTE MYELOID LEUKEMIA: TREATMENT OVER 60, Reviews in Clinical and Experimental Hematology, vol.94, issue.1, pp.46-59, 2002.
DOI : 10.1016/S0145-2126(01)00145-X

J. Krönke, « Monitoring of Minimal Residual Disease in NPM1-Mutated Acute

E. Jourdan, Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia, Blood, vol.121, issue.12
DOI : 10.1182/blood-2012-10-462879

A. K. Burnett, The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: results of the UK MRC AML 10 trial, British Journal of Haematology, vol.340, issue.2
DOI : 10.1038/sj.bmt.1700888

P. Harry and . Erba, « Finding the Optimal Combination Therapy for the Treatment of Newly Diagnosed AML in Older Patients Unfit for Intensive Therapy, 183?91. 41 M. C. Bene et al., « Proposals for the Immunological Classification of Acute Leukemias, 2015.

O. K. Weinberg, Mixed Phenotype Acute Leukemia: A Study of 61 Cases Using World Health Organization and European Group for the Immunological Classification of Leukaemias Criteria, American Journal of Clinical Pathology, vol.142, issue.6, pp.803-811, 2014.
DOI : 10.1309/AJCPPVUPOTUVOIB5

L. D. Monique and . Boer, « A Subtype of Childhood Acute Lymphoblastic Leukaemia with Poor Treatment Outcome: A Genome-Wide Classification Study », The Lancet, pp.125-159, 2009.

C. J. Harrison, Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia, Cytogenetics of Paediatric and Adolescent Acute Lymphoblastic Leukaemia, pp.147-56, 2009.
DOI : 10.3109/10520296209114563

URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2008.07417.x/pdf

P. Stephen, C. G. Hunger, and . Mullighan, « Redefining ALL Classification: Toward Detecting High-Risk ALL and Implementing Precision Medicine, pp.26-3977, 2015.

L. J. Russell, Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia, Blood, vol.114, issue.13, pp.13-2688, 2009.
DOI : 10.1182/blood-2009-03-208397

J. W. Vardiman, The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes, Blood, vol.114, issue.5, pp.937-51, 2009.
DOI : 10.1182/blood-2009-03-209262

C. G. Mullighan, and Prognosis in Acute Lymphoblastic Leukemia, New England Journal of Medicine, vol.360, issue.5, pp.470-80, 2009.
DOI : 10.1056/NEJMoa0808253

C. G. Mullighan, Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia, Nature, vol.38, issue.7137, pp.7137-758, 2007.
DOI : 10.1128/MCB.15.5.2858

K. De and K. , « Exome Sequencing Identifies Mutation in CNOT3 and Ribosomal Genes RPL5 and RPL10 in T-Cell Acute Lymphoblastic Leukemia », Nature Genetics, vol.45, issue.2, pp.186-90, 2013.

T. Trimarchi, Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia, Cell, vol.158, issue.3, pp.593-606, 2014.
DOI : 10.1016/j.cell.2014.05.049

G. Cazzaniga, Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia, Blood, vol.118, issue.20, pp.20-5559
DOI : 10.1182/blood-2011-07-366542

K. Anderson, Genetic variegation of clonal architecture and propagating cells in leukaemia, Nature, vol.69, issue.7330, pp.7330-356, 2011.
DOI : 10.1002/cyto.a.20333

C. G. Mullighan, Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia, Science, vol.101, issue.9, pp.5906-1377, 2008.
DOI : 10.1002/gcc.10305

X. Ma, « Rise and Fall of Subclones from Diagnosis to Relapse in Pediatric

J. Hebert, « Candidate Tumor-Suppressor Genes MTS1 (p16INK4A) and MTS2 (p15INK4B) Display Frequent Homozygous Deletions in Primary Cells from T-but Not from B-Cell Lineage Acute Lymphoblastic Leukemias, pp.12-4038, 1994.

P. Van-vlierberghe and A. Ferrando, The molecular basis of T cell acute lymphoblastic leukemia, Journal of Clinical Investigation, vol.122, issue.10, pp.3398-3406, 2012.
DOI : 10.1172/JCI61269

P. Van-vlierberghe and A. Ferrando, The molecular basis of T cell acute lymphoblastic leukemia, Journal of Clinical Investigation, vol.122, issue.10, pp.3398-3406, 2012.
DOI : 10.1172/JCI61269

J. Zhang, The genetic basis of early T-cell precursor acute lymphoblastic leukaemia, Nature, vol.19, issue.7380, pp.7380-157, 2012.
DOI : 10.1101/gr.092759.109

F. Huguet, Pediatric-Inspired Therapy in Adults With Philadelphia Chromosome???Negative Acute Lymphoblastic Leukemia: The GRAALL-2003 Study, Journal of Clinical Oncology, vol.27, issue.6, pp.911-929, 2009.
DOI : 10.1200/JCO.2008.18.6916

K. Beldjord, Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia, Blood, vol.123, issue.24, pp.24-3739, 2014.
DOI : 10.1182/blood-2014-01-547695

URL : http://www.bloodjournal.org/content/bloodjournal/123/24/3739.full.pdf

C. Pui and W. E. Evans, Treatment of Acute Lymphoblastic Leukemia, Treatment of Acute Lymphoblastic Leukemia, pp.166-78, 2006.
DOI : 10.1056/NEJMra052603

A. K. Fielding and A. Fielding, The Treatment of Adults with Acute Lymphoblastic Leukemia, Hematology, vol.2008, issue.1
DOI : 10.1182/asheducation-2008.1.381

F. Huguet, Clofarabine for the treatment of adult acute lymphoid leukemia: the Group for Research on Adult Acute Lymphoblastic Leukemia intergroup, Leukemia & Lymphoma, vol.114, issue.1, pp.847-57, 2015.
DOI : 10.1002/ajh.23167

J. Chia-ching, L. D. Wang, and . Kaplan, « Clinical Management of HIV-Associated Hematologic Malignancies, Expert Review of Hematology, vol.9, issue.4, pp.361-76, 2016.

H. Tilly, Intensive conventional chemotherapy (ACVBP regimen) compared with standard CHOP for poor-prognosis aggressive non-Hodgkin lymphoma, Blood, vol.102, issue.13, pp.13-4284, 2003.
DOI : 10.1182/blood-2003-02-0542

URL : http://www.bloodjournal.org/content/bloodjournal/102/13/4284.full.pdf

F. Reyes, ACVBP versus CHOP plus Radiotherapy for Localized Aggressive Lymphoma, New England Journal of Medicine, vol.352, issue.12, pp.12-1197, 2005.
DOI : 10.1056/NEJMoa042040

A. Noy and «. Update, Update in HIV-associated lymphoma, HIV-Associated Lymphoma, pp.450-54, 2004.
DOI : 10.1097/00001622-200409000-00007

N. Mounier, « AIDS-Related Non-Hodgkin Lymphoma: Final Analysis of 485
DOI : 10.1182/blood-2005-09-3600

URL : http://www.bloodjournal.org/content/bloodjournal/107/10/3832.full.pdf

S. Lim, AIDS-Related Burkitt's Lymphoma Versus Diffuse Large-Cell Lymphoma in the Pre???Highly Active Antiretroviral Therapy (HAART) and HAART Eras: Significant Differences in Survival With Standard Chemotherapy, Journal of Clinical Oncology, vol.23, issue.19, pp.19-4430, 2005.
DOI : 10.1200/JCO.2005.11.973

C. Hoffmann, AIDS-associated Burkitt or Burkitt-like lymphoma: Short intensive polychemotherapy is feasible and effective, Leukemia & Lymphoma, vol.88, issue.9, pp.1872-80, 2006.
DOI : 10.1002/cncr.11628

J. Gabarre, « High-Dose Therapy plus Autologous Hematopoietic Stem Cell Transplantation for Human Immunodeficiency Virus (HIV)-Related Lymphoma: Results and Impact on HIV Disease, Haematologica, vol.89, issue.9, pp.1100-1108, 2004.

A. Re, High-Dose Therapy and Autologous Peripheral-Blood Stem-Cell Transplantation As Salvage Treatment for HIV-Associated Lymphoma in Patients Receiving Highly Active Antiretroviral Therapy, Journal of Clinical Oncology, vol.21, issue.23, pp.23-4423, 2003.
DOI : 10.1200/JCO.2003.06.039

G. Hütter, « Long-Term Control of HIV by CCR5 Delta32, Delta32 Stem-Cell Transplantation The New England Journal of Medicine, vol.360, issue.7, 2009.

M. David and . Aboulafia, Acute Myeloid Leukemia in Patients Infected with HIV-1 « Acute Myeloid Leukaemia in Human Immunodeficiency Virus-Infected Adults: Epidemiology, Treatment Feasibility and Outcome, 865?76. 77 L 900?908. 78 « Rapport 2010 sur la prise en charge médicale des personnes infectées par le VIH sous la direction du Pr Patrick Yeni», disponible sur, 2001.

L. Sofie and G. Østgård, « Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia: A National Population-Based Cohort Study, Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, vol.33, pp.31-3641, 2015.

K. Takahashi, Clinical and cytogenetic characteristics of myelodysplastic syndrome in patients with HIV infection, Leukemia Research, vol.36, issue.11, pp.1376-79, 2012.
DOI : 10.1016/j.leukres.2012.08.003

J. E. Churpek, Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia, Blood, vol.126, issue.22, pp.22-2484, 2015.
DOI : 10.1182/blood-2015-04-641100

T. Gamal, N. M. Ali, . Al-azhary, and A. Et-doha, Mokhtar, « Frequency and Prognostic Significant of CYP3A4-A-290G Polymorphism in Acute Myeloid Leukemia): 657?61. 83 L. Kinlen, « Evidence for an Infective Cause of Childhood Leukaemia: Comparison of a Scottish New Town with Nuclear Reprocessing Sites in Britain, Journal of Advanced Research Lancet, vol.5, issue.6, pp.8624-1323, 1988.

L. Kinlen and «. , Infections and immune factors in cancer: the role of epidemiology, Oncogene, vol.23, issue.38, pp.38-6341, 2004.
DOI : 10.1038/sj.bjc.6601027

R. Dolcetti, A lymphomagenic role for HIV beyond immune suppression?, Blood, vol.127, issue.11, pp.1403-1412, 2016.
DOI : 10.1182/blood-2015-11-681411

URL : http://www.bloodjournal.org/content/bloodjournal/127/11/1403.full.pdf

. Aboulafia, Acute Myeloid Leukemia in Patients Infected with HIV-1 ». 88 A « Relationship between Acute Myelomonoblastic Leukemia and Infection due to Human Immunodeficiency Virus, 254?56. 89 C. M. Farber et al., « Chemotherapy of Acute Myeloblastic Leukemia in an HIV Carrier, p.180, 1991.

C. C. Carter, HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs, Nature Medicine, vol.142, issue.4, pp.446-51, 2010.
DOI : 10.1038/nm.2109

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892382/pdf

. Takahashi, Clinical and cytogenetic characteristics of myelodysplastic syndrome in patients with HIV infection, Leukemia Research, vol.36, issue.11, pp.36-2012
DOI : 10.1016/j.leukres.2012.08.003

F. Maldarelli, Specific HIV integration sites are linked to clonal expansion and persistence of infected cells, Science, vol.28, issue.5, pp.6193-179, 2014.
DOI : 10.1038/nbt.1630

M. Ba?kiewicz-masiuk and B. Machali?ski, The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells, 420?29. 94 « Rapport Morlat 2013 », disponible sur, 2004.
DOI : 10.1038/sj.onc.1204086

. Aboulafia, Acute myeloid leukemia in patients infected with HIV-1, AIDS, vol.16, issue.6, 2002.
DOI : 10.1097/00002030-200204120-00006

M. E. Charlson, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation, Journal of Chronic Diseases, vol.40, issue.5, pp.373-83, 1987.
DOI : 10.1016/0021-9681(87)90171-8

J. Chia-ching, L. D. Wang, and . Kaplan, « Clinical Management of HIV-Associated Hematologic Malignancies, Expert Review of Hematology, vol.9, issue.4, pp.361-76, 2016.

A. M. Levine, Liposome-Encapsulated Doxorubicin in Combination With Standard Agents (cyclophosphamide, vincristine, prednisone) in Patients With Newly Diagnosed AIDS-Related Non-Hodgkin's Lymphoma: Results of Therapy and Correlates of Response, Journal of Clinical Oncology, vol.22, issue.13, pp.13-2662, 2004.
DOI : 10.1200/JCO.2004.10.093

M. Hentrich, « Therapy of HIV-Associated Lymphoma-Recommendations of the Oncology Working Group of the German Study Group of Physicians in Private Practice Treating HIV-Infected Patients (DAGNÄ), Cooperation with the German AIDS Society (DAIG) », Annals of Hematology 93, pp.913-934, 2014.

J. Gabarre, Chemotherapy combined with zidovudine and GM-CSF in human immunodeficiency virus-related non-Hodgkin's lymphoma, Annals of Oncology, vol.6, issue.10, pp.10-1025, 1995.
DOI : 10.1093/oxfordjournals.annonc.a059067

R. F. Little, AIDS-related Non-Hodgkin's Lymphoma: Etiology, Epidemiology, and Impact of Highly Active Antiretroviral Therapy, Leukemia & Lymphoma, vol.49, issue.sup3, pp.63-68, 2003.
DOI : 10.1056/NEJM199501193320303

N. Mounier, M. Spina, and C. Gisselbrecht, Modern management of non-Hodgkin lymphoma in HIV-infected patients, British Journal of Haematology, vol.3, issue.3, pp.685-98, 2007.
DOI : 10.1002/cncr.11628

R. A. Legarth, Long-Term Mortality in HIV-Infected Individuals 50 Years or Older, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.71, issue.2, pp.213-231, 1999.
DOI : 10.1097/QAI.0000000000000825

URL : http://pdfs.journals.lww.com/jaids/2016/02010/Long_Term_Mortality_in_HIV_Infected_Individuals_50.14.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1504922720766;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21Csk0OpQi3YbjEMdSoz2UhVybFqQxA7lKwSUlA502zQZr96TQRwhVlocEp/sJ586aVbcBFlltKNKo+tbuMfL73hiPqJliudqs17cHeLcLbV/CqjlP3IO0jGHlHQtJWcICDdAyGJMnpi6RlbEJaRheGeh5z5uvqz3FLHgPKVXJzd6bJ6MpiaVkcgjermVhjGDW8+UCG+GjPz8C2GfpvRhHY=;hash|X0eo2hcXEFP57Xp9gCragQ==

N. Obel, Impact of Non-HIV and HIV Risk Factors on Survival in HIV-Infected Patients on HAART: A Population-Based Nationwide Cohort Study, PLoS ONE, vol.46, issue.7, p.22698, 2011.
DOI : 10.1371/journal.pone.0022698.t002

K. Bhaskaran, Changes in the Risk of Death After HIV Seroconversion Compared With Mortality in the General Population, 51?59. 106 H. Bower et al., « Continued Improvement in Survival of Acute Myeloid Leukemia Patients: An Application of the Loss in Expectation of Life, p.390, 2008.
DOI : 10.1001/jama.300.1.51

A. Prehn, Z. , and S. C. Fuchs, « The Need for Reappraisal of AIDS Score Weight of Charlson Comorbidity Index, Journal of Clinical Epidemiology, vol.60, issue.9, pp.867-68, 2007.

W. Michael and . Evans, « Risk Assessment in Human Immunodeficiency Virus- Associated Acute Myeloid Leukemia, Leukemia & Lymphoma, vol.53, issue.4, pp.660-64, 2012.

R. Anthony, J. W. Cillo, and . Mellors, « Which Therapeutic Strategy Will Achieve a Cure for HIV-1? », Current Opinion in, Virology, vol.18, pp.14-19, 2016.

M. B. Daly, Dual anti-HIV mechanism of clofarabine, Retrovirology, vol.285, issue.1, p.20, 2016.
DOI : 10.1074/jbc.M110.178582

URL : https://retrovirology.biomedcentral.com/track/pdf/10.1186/s12977-016-0254-0?site=retrovirology.biomedcentral.com