J. M. Lopez-pousa, A. Manubens-bertran, W. A. Alpérovitch, and . Rocca, « Prevalence of Parkinsonism and Parkinson's Disease in Europe: The EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's Disease », Journal of Neurology Neurosurgery, and Psychiatry, vol.62, issue.1, pp.10-15, 1997.

A. Samii, J. G. Nutt, and B. R. Ransom, Parkinson's disease, The Lancet, vol.363, issue.9423, pp.1783-93, 2004.
DOI : 10.1016/S0140-6736(04)16305-8

A. J. Hughes, S. E. Daniel, S. Blankson, and A. J. Lees, A Clinicopathologic Study of 100 Cases of Parkinson's Disease, Archives of Neurology, vol.50, issue.2, pp.140-188, 1993.
DOI : 10.1001/archneur.1993.00540020018011

L. V. Kalia and A. E. Lang, Parkinson's disease, The Lancet, vol.386, issue.9996, pp.896-912, 2015.
DOI : 10.1016/S0140-6736(14)61393-3

D. B. Calne, B. J. Snow, and C. Lee, Criteria for diagnosing Parkinson's disease, Annals of Neurology, vol.52, issue.S1, pp.125-152, 1992.
DOI : 10.1212/WNL.40.1.1

C. D. Ward, W. R. Et, and . Gibb, « Research Diagnostic Criteria for Parkinson's Disease », Advances in Neurology, vol.53, pp.245-294, 1990.

A. Benabid, S. Louis, J. Chabardes, P. Mitrofanis, and . Pollak, « Deep Brain Stimulation of the Subthalamic Nucleus for the Treatment of Parkinson's Disease ». The Lancet, pp.67-81, 2009.

J. Gracies, Neuror????ducation des syndromes parkinsoniens, Revue Neurologique, vol.166, issue.2, pp.196-212, 2010.
DOI : 10.1016/j.neurol.2009.10.026

W. Tse, P. G. Frisina, T. D. Hälbig, J. Gracies, L. Liang et al., The Effects of Withdrawal of Dopaminergic Medication in Nursing Home Patients With Advanced Parkinsonism, Journal of the American Medical Directors Association, vol.9, issue.9, pp.670-75, 2008.
DOI : 10.1016/j.jamda.2008.07.001

T. D. Hälbig, S. Assuras, J. Creighton, J. C. Borod, W. Tse et al., Differential role of dopamine in emotional attention and memory: Evidence from Parkinson's disease, Movement Disorders, vol.22, issue.9, pp.1677-83, 2011.
DOI : 10.1002/mds.21205

L. Rocchi, L. Chiari, and F. B. Horak, Effects of deep brain stimulation and levodopa on postural sway in Parkinson's disease, Journal of Neurology, Neurosurgery & Psychiatry, vol.73, issue.3, pp.267-74, 2002.
DOI : 10.1136/jnnp.73.3.267

S. Armand, T. Landis, R. Sztajzel, and P. R. Burkhard, Dyskinesia-induced postural instability in Parkinson's disease, Parkinsonism & Related Disorders, vol.15, issue.5, pp.359-64, 2009.
DOI : 10.1016/j.parkreldis.2008.08.007

J. L. Tillerson, W. M. Caudle, M. E. Reverón, and G. W. Miller, Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease, Neuroscience, vol.119, issue.3, pp.899-911, 2003.
DOI : 10.1016/S0306-4522(03)00096-4

C. D. Marsden, The mysterious motor function of the basal ganglia: The Robert Wartenberg Lecture, Neurology, vol.32, issue.5, pp.514-553, 1982.
DOI : 10.1212/WNL.32.5.514

O. Tucha, K. W. Et, and . Lange, « Effects of Methylphenidate on Kinematic Aspects of Handwriting in Hyperactive Boys », Journal of Abnormal Child Psychology, vol.29, issue.4, pp.351-56, 2001.
DOI : 10.1023/A:1010366014095

M. Samuel, B. A. Ceballos, J. Blin, T. Uema, H. Boecker et al., Evidence for lateral premotor and parietal overactivity in Parkinson's disease during sequential and bimanual movements. A PET study, Brain, vol.120, issue.6, pp.963-976, 1997.
DOI : 10.1093/brain/120.6.963

URL : https://academic.oup.com/brain/article-pdf/120/6/963/17863688/1200963.pdf

M. J. Slavin, J. G. Phillips, and J. L. Bradshaw, Visual cues and the handwriting of older adults: A kinematic analysis., Psychology and Aging, vol.11, issue.3, pp.521-526, 1996.
DOI : 10.1037/0882-7974.11.3.521

G. Stelmach, E. Et-george, and . Stelmach, Basal Ganglia Impairment and Force Control NATO ASI Series 62, Tutorials in Motor Neuroscience, édité par Jean Requin, pp.137-48978, 1007.
DOI : 10.1007/978-94-011-3626-6_12

E. Kunesch, A. Schnitzler, C. Tyercha, S. Knecht, and E. G. Stelmach, Altered force release control in Parkinson's disease, Behavioural Brain Research, vol.67, issue.1, pp.43-49, 1995.
DOI : 10.1016/0166-4328(94)00111-R

J. E. Mclennan, K. Nakano, H. R. Tyler, and R. S. Schwab, Micrographia in Parkinson's disease, Micrographia in Parkinson's Disease, pp.141-52, 1972.
DOI : 10.1016/0022-510X(72)90002-0

H. Ackermann, B. F. Gröne, G. Hoch, and P. W. Schönle, Speech Freezing in Parkinson???s Disease: A Kinematic Analysis of Orofacial Movements by Means of Electromagnetic Articulography, Folia Phoniatrica et Logopaedica, vol.45, issue.2, pp.84-89, 1993.
DOI : 10.1159/000266222

H. Teulings and G. Stelmach, Control of stroke size, peak acceleration, and stroke duration in Parkinsonian handwriting, Human Movement Science, vol.10, issue.2-3, pp.204-226, 1991.
DOI : 10.1016/0167-9457(91)90010-U

A. W. Van-gemmert, H. L. Teulings, J. L. Contreras-vidal, and E. G. Stelmach, Parkinsons disease and the control of size and speed in handwriting, Neuropsychologia, vol.37, issue.6, pp.685-94, 1999.
DOI : 10.1016/S0028-3932(98)00122-5

J. «. Parkinson, An Essay on the Shaking Palsy, The Journal of Neuropsychiatry and Clinical Neurosciences, vol.14, issue.2, pp.223-259, 2002.
DOI : 10.1176/jnp.14.2.223

A. Pick, Ueber eine eigentfimliche Schreibstörung, Mikrographie, in Folge cerebraler Erkrankung, Prag. reed. Wschr, vol.28, pp.1-4, 1903.

M. F. Froment, « De la micrographie dans les états Parkinsoniens postencéphalitiques et des conditions qui sont susceptibles de la modifier», Rev. neurol, vol.37, pp.637-638, 1921.

K. Wilson and S. A. , « The Croonian Lectures on some disorders of motility and of muscle tone, with special reference to the corpus striatum. » The Lancet 206, pp.5318-215, 1925.

A. Letanneux, J. Danna, J. Velay, F. Viallet, and S. Pinto, From micrographia to Parkinson's disease dysgraphia, Movement Disorders, vol.1, issue.37, pp.12-1467, 2014.
DOI : 10.1002/mds.870010304

A. Van-gemmert, H. Teulings, J. Contreras-vidal, and G. Stelmach, Parkinsons disease and the control of size and speed in handwriting, Neuropsychologia, vol.37, issue.6, pp.685-694, 1999.
DOI : 10.1016/S0028-3932(98)00122-5

H. L. Teulings, J. L. Contreras-vidal, G. E. Stelmach, and C. H. Adler, Adaptation of handwriting size under distorted visual feedback in patients with Parkinson's disease and elderly and young controls, Journal of Neurology, Neurosurgery & Psychiatry, vol.72, issue.3, pp.315-339, 2002.
DOI : 10.1136/jnnp.72.3.315

W. G. Ondo, P. Et, and . Satija, Withdrawal of visual feedback improves micrographia in Parkinson's disease, Movement Disorders, vol.72, issue.14, pp.14-2130, 2007.
DOI : 10.1212/WNL.44.2.319

S. Rosenblum, M. Samuel, S. Zlotnik, I. Erikh, and I. Schlesinger, Handwriting as an objective tool for Parkinson???s disease diagnosis, Journal of Neurology, vol.13, issue.Suppl 3:III, pp.2357-61, 2013.
DOI : 10.1016/S0268-0033(97)00040-5

O. Tucha, L. Mecklinger, J. Thome, A. Reiter, G. L. Alders et al., Kinematic analysis of dopaminergic effects on skilled handwriting movements in Parkinson???s disease, Journal of Neural Transmission, vol.120, issue.[Suppl 3], pp.609-632, 1996.
DOI : 10.1212/WNL.32.5.514

O. Hornykiewicz, Parkinsons disease and its chemotherapy, Biochemical Pharmacology, vol.24, issue.10, pp.1061-65
DOI : 10.1016/0006-2952(75)90190-2

E. Hutin, N. Bayle, T. Santiago, S. Joudoux, and J. Gracies, Intra- and inter-rater reliability of the 20-meter ambulation test in Parkinson's disease, Annals of Physical and Rehabilitation Medicine, vol.58, issue.S1, p.155, 2015.
DOI : 10.1016/j.rehab.2015.07.369

A. W. Van-gemmert, C. H. Adler, and G. E. Stelmach, Parkinson's disease patients undershoot target size in handwriting and similar tasks, Journal of Neurology, Neurosurgery & Psychiatry, vol.74, issue.11, pp.1502-1510, 2003.
DOI : 10.1136/jnnp.74.11.1502

G. Becker, A. Müller, S. Braune, T. Büttner, R. Benecke et al., Jürgen Rieke, et Reiner Thümler. « Early Diagnosis of Parkinson's Disease », Journal of Neurology, vol.249, pp.40-48, 2002.

A. Berardelli, J. C. Rothwell, P. D. Thompson, and E. M. Hallett, Pathophysiology of bradykinesia in Parkinson's disease, Pathophysiology of Bradykinesia in Parkinson's Disease, pp.2131-2177, 2001.
DOI : 10.1093/brain/124.11.2131

J. Gracies, M. Diwan, A. Lewthwaite, M. Toma, D. Weisz et al., « Large versus small rapid alternating movements: quantitative testing in Parkinson's disease using the Hand Tapper, Park Dis Rel Dis, vol.7, issue.S45, 2001.

H. L. Teulings, J. L. Contreras-vidal, G. E. Stelmach, and C. H. Adler, Parkinsonism Reduces Coordination of Fingers, Wrist, and Arm in Fine Motor Control, Parkinsonism Reduces Coordination of Fingers, Wrist, and Arm in Fine Motor Control, pp.159-70, 1997.
DOI : 10.1006/exnr.1997.6507

J. A. Robichaud, K. D. Pfann, C. L. Comella, M. Brandabur, and D. M. Corcos, « Greater Impairment of Extension Movements as Compared to Flexion Movements in Parkinson's Disease », Experimental Brain Research, vol.156, issue.2, pp.240-54, 2004.

C. Pauwels, C. Van-reeth, N. Bayle, T. Santiago, S. Joudoux et al., Getting up from the ground in Parkinson's disease: Effects of a standardized intensive physical therapy program, Annals of Physical and Rehabilitation Medicine, vol.57, p.363, 2014.
DOI : 10.1016/j.rehab.2014.03.1212

W. Almangour, A. Calvalido, C. Pauwels, E. Hutin, N. Bayle et al., Effects of an intensive physical therapy program on a marker of Parkinson's disease: Alternate forearm pronation/supination movements of large vs small amplitude, Annals of Physical and Rehabilitation Medicine, vol.57, pp.362-63, 2014.
DOI : 10.1016/j.rehab.2014.03.1211

A. Calvalido, W. Almangour, C. Pauwels, E. Hutin, N. Bayle et al., Effects on an intensive physical therapy program on spiralography in Parkinson's disease, Annals of Physical and Rehabilitation Medicine, vol.57, pp.57-362, 2014.
DOI : 10.1016/j.rehab.2014.03.1210