B. Vellas, Chutes, fragilité et ostéoporose chez la personne âgée : un problème de santé publique [Internet]
DOI : 10.1016/s0248-8663(00)80006-5

. Trivalle, Vieillissement normal : mythe ou réalité ? -La revue du praticien - Médecine générale [Internet], 2004.

. Trivalle, Le syndrome de fragilité en gériatrie -Médecine&Hygiène [Internet], 2000.

J. Morley, B. Vellas, A. Van-kan, G. Anker, S. Bauer et al., Frailty Consensus: A Call to Action, Journal of the American Medical Directors Association, vol.14, issue.6, pp.392-399
DOI : 10.1016/j.jamda.2013.03.022

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084863/pdf

G. Kojima, D. Kendrick, D. Skelton, and R. Morris, Frailty predicts short-term incidence of future falls among British community-dwelling older people: a prospective cohort study nested within a randomised controlled trial, BMC Geriatrics, vol.53, issue.12, 2015.
DOI : 10.1111/j.1532-5415.2005.00509.x

G. Kojima, Frailty as a predictor of disabilities among community-dwelling older people: a systematic review and meta-analysis, Disability and Rehabilitation, vol.39, issue.19, pp.1-12, 2016.
DOI : 10.1136/jech-2015-206717

T. Ng, L. Feng, M. Nyunt, L. Feng, M. Niti et al., Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial, The American Journal of Medicine, vol.128, issue.11, pp.1225-1236, 2015.
DOI : 10.1016/j.amjmed.2015.06.017

A. Clegg, J. Young, S. Iliffe, M. Rikkert, and K. Rockwood, Frailty in elderly people. The Lancet, pp.752-62, 2013.

O. Theou, T. Brothers, A. Mitnitski, and K. Rockwood, Operationalization of Frailty Using Eight Commonly Used Scales and Comparison of Their Ability to Predict All-Cause Mortality, Journal of the American Geriatrics Society, vol.46, issue.Suppl 1, pp.1537-51, 2013.
DOI : 10.1016/j.eurger.2012.07.407

L. Fried, C. Tangen, and J. Walston, Frailty in Older Adults: Evidence for a Phenotype, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.56, issue.3, pp.146-156, 2001.
DOI : 10.1093/gerona/56.3.M146

S. Sternberg, A. Schwartz, S. Karunananthan, H. Bergman, M. Clarfield et al., The Identification of Frailty: A Systematic Literature Review, Journal of the American Geriatrics Society, vol.54, issue.Suppl 2, 2011.
DOI : 10.1111/j.1532-5415.2006.00829.x

K. Rockwood, A global clinical measure of fitness and frailty in elderly people, Canadian Medical Association Journal, vol.173, issue.5, pp.489-95, 2005.
DOI : 10.1503/cmaj.050051

K. Bandeen-roche, C. Seplaki, J. Huang, B. Buta, R. Kalyani et al., Frailty in Older Adults: A Nationally Representative Profile in the United States, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.70, issue.11, pp.1427-1461, 2015.
DOI : 10.1093/gerona/glv133

M. Puts, P. Lips, and D. Deeg, Sex Differences in the Risk of Frailty for Mortality Independent of Disability and Chronic Diseases, Journal of the American Geriatrics Society, vol.347, issue.1, pp.40-47, 2005.
DOI : 10.1093/gerona/55.6.M350

B. Vellas, L. Balardy, S. Gillette-guyonnet, A. Van-kan, G. Ghisolfi-marque et al., Looking for frailty in community-dwelling older persons: The Gerontopole Frailty Screening Tool (GFST), The journal of nutrition, health & aging, vol.1, issue.7, 2013.
DOI : 10.1007/s12603-011-0110-9

S. Bagshaw, H. Stelfox, R. Mcdermid, D. Rolfson, R. Tsuyuki et al., Association between frailty and short- and long-term outcomes among critically ill patients: a multicentre prospective cohort study, Canadian Medical Association Journal, vol.186, issue.2, pp.95-102, 2014.
DOI : 10.1503/cmaj.130639

URL : http://www.cmaj.ca/content/186/2/E95.full.pdf

J. Farhat, V. Velanovich, A. Falvo, H. Horst, A. Swartz et al., Are the frail destined to fail? Frailty index as predictor of surgical morbidity and mortality in the elderly, Journal of Trauma and Acute Care Surgery, vol.72, issue.6, pp.1526-1530
DOI : 10.1097/TA.0b013e3182542fab

K. Ensrud, S. Ewing, B. Taylor, H. Fink, K. Stone et al., Frailty and Risk of Falls, Fracture, and Mortality in Older Women: The Study of Osteoporotic Fractures, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.62, issue.7, pp.744-751, 2007.
DOI : 10.1093/gerona/62.7.744

J. Avila-funes, C. Helmer, H. Amieva, P. Barberger-gateau, M. Goff et al., Frailty Among Community-Dwelling Elderly People in France: The Three-City Study, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.63, issue.10, pp.1089-96, 2008.
DOI : 10.1093/gerona/63.10.1089

URL : https://hal.archives-ouvertes.fr/inserm-00336493

K. Rockwood, K. Stadnyk, C. Macknight, I. Mcdowell, R. Hébert et al., A brief clinical instrument to classify frailty in elderly people. The Lancet, pp.205-206, 1999.

N. Ahmed, R. Mandel, and M. Fain, Frailty: An Emerging Geriatric Syndrome, The American Journal of Medicine, vol.120, issue.9, pp.748-53, 2007.
DOI : 10.1016/j.amjmed.2006.10.018

I. Lanièce, P. Couturier, M. Dramé, G. Gavazzi, S. Lehman et al., Incidence and main factors associated with early unplanned hospital readmission among French medical inpatients aged 75 and over admitted through emergency units, Age and Ageing, vol.37, issue.4, pp.416-438, 2008.
DOI : 10.1093/ageing/afn093

N. Macklai, J. Spagnoli, J. Junod, and B. Santos-eggimann, Prospective association of the SHARE-operationalized frailty phenotype with adverse health outcomes: evidence from 60+ community-dwelling Europeans living in 11 countries, BMC Geriatrics, vol.60, issue.11, p.1, 2013.
DOI : 10.1007/s12603-011-0075-8

S. Wang, T. Shamliyan, K. Talley, R. Ramakrishnan, and R. Kane, Not just specific diseases: Systematic review of the association of geriatric syndromes with hospitalization or nursing home admission, Archives of Gerontology and Geriatrics, vol.57, issue.1, 2013.
DOI : 10.1016/j.archger.2013.03.007

O. De-vries, G. Peeters, P. Lips, and D. Deeg, Does frailty predict increased risk of falls and fractures? A prospective population-based study, Osteoporosis International, vol.10, issue.3, 2013.
DOI : 10.1016/j.arr.2010.09.001

G. Kojima, Frailty as a predictor of fractures among community-dwelling older people: A systematic review and meta-analysis, Bone, vol.90, pp.116-138, 2016.
DOI : 10.1016/j.bone.2016.06.009

H. Autorité and D. Santé, Comment repérer la fragilité en soins ambulatoires ? [Internet]. [cited, 2016.

G. Ellis, M. Whitehead, O. Neill, D. Langhorne, P. Robinson et al., Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev, p.6211, 2011.
DOI : 10.1002/14651858.cd006211

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164377/pdf

H. Autorité and D. Santé, Comment prendre en charge les personnes âgées fragiles en ambulatoire? [Internet]. [cited, 2016.

J. Wilson, G. Jungner, and W. Organization, Principes et pratique du dépistage des maladies, 1970.

L. Amalou, F. Roca, F. François, L. Druesne, R. Langlois et al., Tracking tool for frailty: ABCDEF. Geriatr Psychol Neuropsychiatr Vieil, pp.287-95, 2016.

L. Amalou and P. Chassagne, Validation d'un outil de repérage de la fragilité gériatrique dans une population communautaire ambulatoire de sujets âges, 2013.

F. François, Intérêt d'une évaluation gériatrique siomplifiée péri-opératoire des malades traités pour une fracture du col fémoral

L. Vincent, Dépistage de la fragilité par l'outil « ABCDEF » dans une population de sujets âgés en consultation de médecine générale [Thèse d'exercice de médecine générale]

T. Ng, L. Feng, M. Nyunt, A. Larbi, and K. Yap, Frailty in Older Persons: Multisystem Risk Factors and the Frailty Risk Index (FRI), Journal of the American Medical Directors Association, vol.15, issue.9, 2014.
DOI : 10.1016/j.jamda.2014.03.008

I. Widagdo, N. Pratt, M. Russell, and E. Roughead, Predictive performance of four frailty measures in an older Australian population, Age and Ageing, vol.44, issue.6, pp.967-72, 2015.
DOI : 10.1093/ageing/afv144

P. Forti, E. Rietti, N. Pisacane, V. Olivelli, B. Maltoni et al., A comparison of frailty indexes for prediction of adverse health outcomes in an elderly cohort, Archives of Gerontology and Geriatrics, vol.54, issue.1, pp.16-20, 2012.
DOI : 10.1016/j.archger.2011.01.007

K. Ensrud, S. Ewing, B. Taylor, H. Fink, P. Cawthon et al., Comparison of 2 Frailty Indexes for Prediction of Falls, Disability, Fractures, and Death in Older Women, Archives of Internal Medicine, vol.168, issue.4, pp.382-391, 2008.
DOI : 10.1001/archinternmed.2007.113

K. Ensrud, S. Ewing, P. Cawthon, H. Fink, B. Taylor et al., A Comparison of Frailty Indexes for the Prediction of Falls, Disability, Fractures, and Mortality in Older Men, Journal of the American Geriatrics Society, vol.18, issue.3, pp.492-500, 2009.
DOI : 10.1007/978-1-4899-4541-9

S. Sternberg, W. Schwartz, A. Karunananthan, S. Bergman, H. et al., The Identification of Frailty: A Systematic Literature Review, Journal of the American Geriatrics Society, vol.54, issue.Suppl 2, pp.2129-2167, 2011.
DOI : 10.1111/j.1532-5415.2006.00829.x

N. Peel, Epidemiology of Falls in Older Age, Canadian Journal on Aging / La Revue canadienne du vieillissement, vol.44, issue.01, pp.7-19, 2011.
DOI : 10.1093/gerona/gln035

A. Lecroart, O. Froment, C. Marbot, and D. Roy, Projection des populations âgées dépendantes : deux méthodes d'estimation -Dossiers solidarité et santé -Ministère des Affaires sociales et de la Santé, 2017.

F. Brivet, J. Guy, P. Galanaud, and J. Dormont, Personnes âgées et urgences médicales d'un centre hospitalier universitaire Available from: https://www.researchgate, 1992.
DOI : 10.1016/s1164-6756(05)80500-6

. Fanello-s and L. Moutel, Analyse de la prise en charge des personnes âgées de 75 ans et plus par le service des Admissions et Urgences d'un grand Hôpital, 1997.

T. Shamliyan, K. Talley, R. Ramakrishnan, and R. Kane, Association of frailty with survival: A systematic literature review, Ageing Research Reviews, vol.12, issue.2, pp.719-755, 2013.
DOI : 10.1016/j.arr.2012.03.001

L. Rubenstein, Falls in older people: epidemiology, risk factors and strategies for prevention, Age and Ageing, vol.35, issue.suppl_2, pp.37-41, 2006.
DOI : 10.1093/ageing/afl084

. Deméocq, Chute du sujet âgé : Prévalence et parcours de soins en médecine générale. Poster presented at

M. Cheng and S. Chang, Frailty as a Risk Factor for Falls Among Community Dwelling People: Evidence From a Meta-Analysis, Journal of Nursing Scholarship, vol.5, issue.1, 2017.
DOI : 10.1080/tam.5.1.1.37

J. Avila-funes, C. Helmer, H. Amieva, P. Barberger-gateau, L. Goff et al., Frailty Among Community-Dwelling Elderly People in France: The Three-City Study, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.63, issue.10, pp.1089-96, 2008.
DOI : 10.1093/gerona/63.10.1089

URL : https://hal.archives-ouvertes.fr/inserm-00336493

B. Vellas, Repérage et maintien de l'autonomie des peronnes âgées fragiles. Livre blanc, 2015.

Z. Zheng, S. Guan, H. Ding, Z. Wang, J. Zhang et al., Prevalence and Incidence of Frailty in Community-Dwelling Older People: Beijing Longitudinal Study of Aging II, Journal of the American Geriatrics Society, vol.13, issue.6, pp.1281-1287
DOI : 10.1186/s12916-014-0255-6

M. Bartley, Y. Geda, T. Christianson, V. Pankratz, R. Roberts et al., Frailty and Mortality Outcomes in Cognitively Normal Older People: Sex Differences in a Population-Based Study, Journal of the American Geriatrics Society, vol.4, issue.1, pp.132-139, 2016.
DOI : 10.1016/j.eurger.2013.06.005

K. Brody, R. Johnson, L. Ried, P. Carder, and N. Perrin, A Comparison of Two Methods for Identifying Frail Medicare-Aged Persons, Journal of the American Geriatrics Society, vol.2, issue.3, pp.562-571, 2002.
DOI : 10.1001/archpsyc.1989.01810070090014

F. Nourashemi, S. Andrieu, S. Guyonnet, and H. Grandjean, Instrumental Activities of Daily Living as a Potential Marker of Frailty: A Study of 7364 Community-Dwelling Elderly Women (the EPIDOS Study), The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.56, issue.7, pp.448-453, 2001.
DOI : 10.1093/gerona/56.7.M448

B. Vellas, S. Gillette-guyonnet, F. Nourhashémi, Y. Rolland, S. Lauque et al., Chutes, fragilité et ostéoporose chez la personne âgée: un problème de santé publique. Rev Médecine Interne, pp.608-621, 2000.
DOI : 10.1016/s0248-8663(00)80006-5

D. Buyser, S. Petrovic, M. Taes, Y. Vetrano, D. Onder et al., A Multicomponent Approach to Identify Predictors of Hospital Outcomes in Older In-Patients: A Multicentre, Observational Study, PLoS ONE, vol.279, issue.12, p.115413, 2014.
DOI : 10.1371/journal.pone.0115413.s003

P. Lang, D. Heitz, G. Hédelin, M. Dramé, N. Jovenin et al., Early Markers of Prolonged Hospital Stays in Older People: A Prospective, Multicenter Study of 908 Inpatients in French Acute Hospitals, Journal of the American Geriatrics Society, vol.47, issue.(2, pp.1031-1040, 2006.
DOI : 10.1111/j.1532-5415.1999.tb02566.x

M. Correia and D. Waitzberg, The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis, Clinical Nutrition, vol.22, issue.3, pp.235-244, 2003.
DOI : 10.1016/S0261-5614(02)00215-7

H. Makizako, H. Shimada, T. Doi, K. Tsutsumimoto, and T. Suzuki, Impact of physical frailty on disability in community-dwelling older adults: a prospective cohort study, BMJ Open, vol.19, issue.9, p.8462, 2015.
DOI : 10.1377/hlthaff.19.3.26

M. Puts, P. Lips, and D. Deeg, Sex Differences in the Risk of Frailty for Mortality Independent of Disability and Chronic Diseases, Journal of the American Geriatrics Society, vol.347, issue.1, 2005.
DOI : 10.1093/gerona/55.6.M350

M. Fiatarone, O. Neill, E. Ryan, N. Clements, K. Solares et al., Exercise Training and Nutritional Supplementation for Physical Frailty in Very Elderly People, New England Journal of Medicine, vol.330, issue.25, pp.1769-75, 1994.
DOI : 10.1056/NEJM199406233302501

J. Michel, A. Cruz-jentoft, and C. T. Frailty, Frailty, Exercise and Nutrition, Clinics in Geriatric Medicine, vol.31, issue.3, pp.375-87
DOI : 10.1016/j.cger.2015.04.006

C. Kim and K. Lee, Preventive Effect of Protein-Energy Supplementation on the Functional Decline of Frail Older Adults With Low Socioeconomic Status: A Community-Based Randomized Controlled Study, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.68, issue.3, 2013.
DOI : 10.1093/gerona/gls167

N. Macklai, J. Spagnoli, J. Junod, and B. Santos-eggimann, Prospective association of the SHARE-operationalized frailty phenotype with adverse health outcomes: evidence from 60+ community-dwelling Europeans living in 11 countries, BMC Geriatrics, vol.60, issue.11, p.3, 2013.
DOI : 10.1007/s12603-011-0075-8

D. Iorio, A. Longo, A. , M. Costanza, A. Bandinelli et al., Characteristics of geriatric patients related to early and late readmissions to hospital, Aging Milan Italy, vol.10, issue.4, pp.339-385, 1998.

L. Lahousse, B. Maes, G. Ziere, D. Loth, V. Verlinden et al., Adverse outcomes of frailty in the elderly: the Rotterdam Study, European Journal of Epidemiology, vol.53, issue.12, 2014.
DOI : 10.1111/j.1532-5415.2005.00509.x

L. Fried, L. Ferrucci, J. Darer, J. Williamson, and G. Anderson, Untangling the Concepts of Disability, Frailty, and Comorbidity: Implications for Improved Targeting and Care, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.59, issue.3, pp.255-63, 2004.
DOI : 10.1093/gerona/59.3.M255

D. Vetrano, A. Foebel, A. Marengoni, V. Brandi, A. Collamati et al., Chronic diseases and geriatric syndromes: The different weight of comorbidity, European Journal of Internal Medicine, vol.27, pp.62-69, 2016.
DOI : 10.1016/j.ejim.2015.10.025

R. Wang, L. Chen, L. Fan, D. Gao, Z. Liang et al., Incidence and Effects of Polypharmacy on Clinical Outcome among Patients Aged 80+: A Five-Year Follow-Up Study, PLOS ONE, vol.19, issue.11, p.142123, 2015.
DOI : 10.1371/journal.pone.0142123.t003

S. Borson, J. Scanlan, P. Chen, and M. Ganguli, The Mini-Cog as a Screen for Dementia: Validation in a Population-Based Sample, Journal of the American Geriatrics Society, vol.53, issue.10, pp.1451-1455, 2003.
DOI : 10.1001/archneur.1996.00550100119021

J. Agostini, L. Han, and M. Tinetti, The Relationship Between Number of Medications and Weight Loss or Impaired Balance in Older Adults, Journal of the American Geriatrics Society, vol.79, issue.10, 2004.
DOI : 10.1111/j.1532-5415.1986.tb05480.x

. Polypathologie, Available from, 2008.

H. Autorité and D. Santé, Prescrire chez le sujet âgé [Internet] Available from: https, 2006.

A. Gildas, Place de la conciliation médicamenteuse dans le parcours de soin des sujets âgés hospitalisés Proposition d'un outil d'interface entre l'hôpital et le pharmacien Available from: https, 2017.

K. Saum, B. Schöttker, A. Meid, B. Holleczek, W. Haefeli et al., Is Polypharmacy Associated with Frailty in Older People? Results From the ESTHER Cohort Study, Journal of the American Geriatrics Society, vol.30, issue.2, pp.27-32, 2017.
DOI : 10.1007/s40266-013-0064-1

A. Van-kan, G. Rolland, Y. Andrieu, S. Bauer, J. Beauchet et al., Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force, The journal of nutrition, health & aging, vol.26, issue.10, pp.881-890, 2009.
DOI : 10.1093/gerona/60.7.894

L. Santamaría, A. , J. Giménez, P. , B. Satorra et al., Prevalence and associated factors of falls in communitydwelling elderly]. Aten Primaria, pp.367-75, 2015.

J. Woo, J. Leung, and J. Morley, Comparison of Frailty Indicators Based on Clinical Phenotype and the Multiple Deficit Approach in Predicting Mortality and Physical Limitation, Journal of the American Geriatrics Society, vol.59, issue.8, pp.1478-86, 2012.
DOI : 10.1111/j.1532-5415.2011.03336.x

J. Sanders, M. Bremmer, H. Comijs, P. Van-de-ven, D. Deeg et al., Gait Speed and Processing Speed as Clinical Markers for Geriatric Health Outcomes, The American Journal of Geriatric Psychiatry, vol.25, issue.4, pp.374-85
DOI : 10.1016/j.jagp.2016.12.003

M. Puts, P. Lips, and D. Deeg, Sex Differences in the Risk of Frailty for Mortality Independent of Disability and Chronic Diseases, Journal of the American Geriatrics Society, vol.347, issue.1, 2005.
DOI : 10.1093/gerona/55.6.M350

S. Borson, J. Scanlan, J. Watanabe, S. Tu, and M. Lessig, Simplifying Detection of Cognitive Impairment: Comparison of the Mini-Cog and Mini-Mental State Examination in a Multiethnic Sample, Journal of the American Geriatrics Society, vol.138, issue.5, pp.871-875, 2005.
DOI : 10.1212/WNL.34.7.939

. La-prise-en-charge-de-la-maladie, Alzheimer et des maladies apparentées -Sénat [Internet]. [cited Available from: http://www.senat.fr/notice- rapport, 2004.