.. Gravité-d-'un-Épisode, durée d'hospitalisation et virus, p.38

E. Bamberger, I. Srugo, A. Raya, B. Segal, E. et al., What is the clinical relevance of respiratory syncytial virus bronchiolitis?: findings from a multi-center, prospective study, European Journal of Clinical Microbiology & Infectious Diseases, vol.28, issue.44, pp.3323-3353, 2012.
DOI : 10.1097/INF.0b013e31818ee0c1

M. Berry, J. Gamieldien, and B. Fielding, Identification of New Respiratory Viruses in the New Millennium, Viruses, vol.121, issue.3, pp.996-1019, 2015.
DOI : 10.1097/INF.0b013e31827fef67

C. Calvo, M. García-garcía, F. Pozo, G. Paula, M. Molinero et al., Respiratory Syncytial Virus Coinfections With Rhinovirus and Human Bocavirus in Hospitalized Children, Medicine, vol.94, issue.42, p.1788, 2015.
DOI : 10.1097/MD.0000000000001788

C. Calvo, F. Pozo, M. García-garcía, M. Sanchez, M. Lopez-valero et al., Detection of new respiratory viruses in hospitalized infants with bronchiolitis: a three-year prospective study, Acta Paediatrica, vol.15, issue.Suppl 3, pp.883-890, 2010.
DOI : 10.3201/eid1311.070793

D. Che, J. Nicolau, J. Bergounioux, T. Perez, and D. Bitar, Bronchiolite aigu?? du nourrisson en France??: bilan des cas hospitalis??s en 2009??et facteurs de l??talit??, Archives de P??diatrie, vol.19, issue.7, pp.700-706, 2012.
DOI : 10.1016/j.arcped.2012.04.015

J. Devincenzo, T. Wilkinson, A. Vaishnaw, J. Cehelsky, R. Meyers et al., Viral Load Drives Disease in Humans Experimentally Infected with Respiratory Syncytial Virus, American Journal of Respiratory and Critical Care Medicine, vol.182, issue.10, pp.1305-1319, 2010.
DOI : 10.1093/infdis/169.6.1368

F. Ducharme, D. Chalut, L. Plotnick, C. Savdie, D. Kudirka et al., The Pediatric Respiratory Assessment Measure: A Valid Clinical Score for Assessing Acute Asthma Severity from Toddlers to Teenagers, The Journal of Pediatrics, vol.152, issue.4, pp.476-480, 2008.
DOI : 10.1016/j.jpeds.2007.08.034

I. Engelmann, C. Mordacq, P. Gosset, I. Tillie-leblond, A. Dewilde et al., Rhinovirus and Asthma: Reinfection, Not Persistence, American Journal of Respiratory and Critical Care Medicine, vol.188, issue.9, pp.1165-1172, 2013.
DOI : 10.1128/JCM.00993-09

M. Finianos, R. Issa, M. Curran, C. Afif, M. Rajab et al., Etiology, seasonality, and clinical characterization of viral respiratory infections among hospitalized children in Beirut, Lebanon, Journal of Medical Virology, vol.57, issue.11, pp.1874-81, 2016.
DOI : 10.1159/000365758

E. Goka, P. Vallely, K. Mutton, and P. Klapper, Single and multiple respiratory virus infections and severity of respiratory disease: A systematic review, Paediatric Respiratory Reviews, vol.15, issue.4, pp.363-70, 2014.
DOI : 10.1016/j.prrv.2013.11.001

K. Hasegawa, O. Dumas, T. Hartert, and C. Camargo, Advancing our understanding of infant bronchiolitis through phenotyping and endotyping: clinical and molecular approaches, Expert Review of Respiratory Medicine, vol.372, issue.2, pp.891-900, 2016.
DOI : 10.1186/s12890-015-0040-0

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975526/pdf

K. Hasegawa, J. Mansbach, S. Teach, E. Fisher, D. Hershey et al., Multicenter Study of Viral Etiology and Relapse in Hospitalized Children With Bronchiolitis, The Pediatric Infectious Disease Journal, vol.33, issue.8, pp.809-822, 2014.
DOI : 10.1097/INF.0000000000000293

J. Henderson, T. Hilliard, A. Sherriff, D. Stalker, A. Shammari et al., Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: A longitudinal birth cohort study, Pediatric Allergy and Immunology, vol.79, issue.5, pp.386-92, 2005.
DOI : 10.1086/344310

A. Hotard, E. Laikhter, K. Brooks, T. Hartert, and M. Moore, ABSTRACT, Journal of Virology, vol.89, issue.16, pp.8258-66, 2015.
DOI : 10.1128/JVI.01045-15

D. Jackson, R. Gangnon, M. Evans, K. Roberg, E. Anderson et al., Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children, American Journal of Respiratory and Critical Care Medicine, vol.178, issue.7, pp.667-72, 2008.
DOI : 10.1016/j.jaci.2007.05.050

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556448/pdf

T. Jartti and J. Gern, Role of viral infections in the development and exacerbation of asthma in children, Journal of Allergy and Clinical Immunology, vol.140, issue.4, pp.895-906, 2017.
DOI : 10.1016/j.jaci.2017.08.003

T. Jartti, P. Lehtinen, T. Vuorinen, M. Koskenvuo, and O. Ruuskanen, Persistence of rhinovirus and enterovirus RNA after acute respiratory illness in children, Journal of Medical Virology, vol.72, issue.4, pp.695-704, 2004.
DOI : 10.1002/jmv.20027

L. Jensen, E. Walker, D. Jans, and R. Ghildyal, Proteases of Human Rhinovirus: Role in Infection, Methods Mol Biol, vol.1221, pp.129-170, 2015.
DOI : 10.1007/978-1-4939-1571-2_10

Y. Kawasaki, Y. Aoyagi, Y. Abe, H. Go, T. Imamura et al., Serum KL-6 levels as a biomarker of lung injury in respiratory syncytial virus bronchiolitis, Journal of Medical Virology, vol.26, issue.12, pp.2104-2112, 2009.
DOI : 10.1164/ajrccm/148.3.637

K. Kloepfer, W. Lee, T. Pappas, T. Kang, R. Vrtis et al., Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations, Journal of Allergy and Clinical Immunology, vol.133, issue.5, pp.1301-1308, 2014.
DOI : 10.1016/j.jaci.2014.02.030

A. Kotaniemi-syrjänen, R. Vainionpää, T. Reijonen, M. Waris, K. Korhonen et al., Rhinovirus-induced wheezing in infancy???the first sign of childhood asthma?, Journal of Allergy and Clinical Immunology, vol.111, issue.1, pp.66-71, 2003.
DOI : 10.1067/mai.2003.33

C. Laurent, A. Dugué, J. Brouard, D. Nimal, D. J. Parienti et al., Viral Epidemiology and Severity of Respiratory Infections in Infants in 2009, The Pediatric Infectious Disease Journal, vol.31, issue.8, pp.827-858, 2012.
DOI : 10.1097/INF.0b013e3182566005

W. Lee, R. Lemanske, M. Evans, F. Vang, T. Pappas et al., Human Rhinovirus Species and Season of Infection Determine Illness Severity, American Journal of Respiratory and Critical Care Medicine, vol.37, issue.9, pp.886-91, 2012.
DOI : 10.1093/infdis/156.1.43

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530215/pdf

J. Mansbach, P. Piedra, S. Teach, A. Sullivan, T. Forgey et al., Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis, Arch Pediatr Adolesc Med. août, vol.166, issue.8, pp.700-706, 2012.

C. Marguet, M. Lubrano, M. Gueudin, L. Roux, P. Deschildre et al., In Very Young Infants Severity of Acute Bronchiolitis Depends On Carried Viruses, PLoS ONE, vol.119, issue.2, p.4596, 2009.
DOI : 10.1371/journal.pone.0004596.t004

N. Mazur, F. Martinón-torres, E. Baraldi, B. Fauroux, A. Greenough et al., Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics, The Lancet Respiratory Medicine, vol.3, issue.11, pp.888-900, 2015.
DOI : 10.1016/S2213-2600(15)00255-6

R. Mehta, M. Scheffler, L. Tapia, L. Aideyan, K. Patel et al., Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity, Influenza and Other Respiratory Viruses, vol.82, issue.6, pp.617-642, 2014.
DOI : 10.1128/JVI.01887-07

H. Meissner, Viral Bronchiolitis in Children, New England Journal of Medicine, vol.374, issue.1, pp.62-72, 2016.
DOI : 10.1056/NEJMra1413456

A. Mejias and O. Ramilo, New options in the treatment of respiratory syncytial virus disease, Journal of Infection, vol.71, pp.80-87, 2015.
DOI : 10.1016/j.jinf.2015.04.025

A. Merianos, C. Dixon, and E. Mahabee-gittens, Secondhand smoke exposure, illness severity, and resource utilization in pediatric emergency department patients with respiratory illnesses, Journal of Asthma, vol.25, issue.5, pp.798-806, 2017.
DOI : 10.1016/j.ypmed.2016.01.003

E. Miller, K. Edwards, G. Weinberg, M. Iwane, M. Griffin et al., A novel group of rhinoviruses is associated with asthma hospitalizations, Journal of Allergy and Clinical Immunology, vol.123, issue.1, pp.98-104, 2009.
DOI : 10.1016/j.jaci.2008.10.007

H. Nair, D. Nokes, B. Gessner, M. Dherani, S. Madhi et al., Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis, The Lancet, vol.375, issue.9725, pp.1545-1555, 2010.
DOI : 10.1016/S0140-6736(10)60206-1

N. Papadopoulos, M. Moustaki, M. Tsolia, A. Bossios, E. Astra et al., Association of Rhinovirus Infection with Increased Disease Severity in Acute Bronchiolitis, American Journal of Respiratory and Critical Care Medicine, vol.165, issue.9, pp.1285-1294, 2002.
DOI : 10.1128/CMR.7.2.143

A. Pedraza-bernal, C. Rodriguez-martinez, and R. Acuña-cordero, Predictors of severe disease in a hospitalized population of children with acute viral lower respiratory tract infections, Journal of Medical Virology, vol.159, issue.5, pp.754-763, 2016.
DOI : 10.1093/aje/kwh090

F. Petruzella and M. Gorelick, Duration of Illness in Infants With Bronchiolitis Evaluated in the Emergency Department, PEDIATRICS, vol.126, issue.2, pp.285-90, 2010.
DOI : 10.1542/peds.2009-2189

R. Quinonez, E. Coon, A. Schroeder, and V. Moyer, When technology creates uncertainty: pulse oximetry and overdiagnosis of hypoxaemia in bronchiolitis, BMJ, vol.358, p.3850, 2017.
DOI : 10.1136/bmj.j3850

S. Rhedin, A. Lindstrand, M. Rotzén-Östlund, T. Tolfvenstam, L. Öhrmalm et al., Clinical Utility of PCR for Common Viruses in Acute Respiratory Illness, PEDIATRICS, vol.133, issue.3, pp.538-545, 2014.
DOI : 10.1542/peds.2013-3042

S. Ricart, M. Marcos, M. Sarda, A. A. Muñoz-almagro, C. Pumarola et al., Clinical risk factors are more relevant than respiratory viruses in predicting bronchiolitis severity, Pediatric Pulmonology, vol.49, issue.5, pp.456-63, 2013.
DOI : 10.1016/j.jcv.2010.07.016

M. Ruotsalainen, M. Hyvärinen, E. Piippo-savolainen, and M. Korppi, Adolescent asthma after rhinovirus and respiratory syncytial virus bronchiolitis, Pediatric Pulmonology, vol.185, issue.7, pp.633-642, 2013.
DOI : 10.1164/rccm.201104-0660OC

R. Stein, D. Sherrill, W. Morgan, C. Holberg, M. Halonen et al., Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years, The Lancet, vol.354, issue.9178, pp.541-546, 1999.
DOI : 10.1016/S0140-6736(98)10321-5

H. Stempel, E. Martin, J. Kuypers, J. Englund, and D. Zerr, Multiple viral respiratory pathogens in children with bronchiolitis, Acta Paediatrica, vol.120, issue.4, pp.123-129, 2009.
DOI : 10.3201/eid0903.020289

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605206/pdf

B. Sterling, E. Bosdure, S. Bel, N. Chabrol, B. Dubus et al., Bronchiolite et kin??sith??rapie respiratoire??: un dogme ??branl??, Journal Europ??en des Urgences et de R??animation, vol.27, issue.1, pp.14-20, 2015.
DOI : 10.1016/j.jeurea.2015.02.004

G. Swingler, G. Hussey, and M. Zwarenstein, Duration of Illness in Ambulatory Children Diagnosed With Bronchiolitis, Archives of Pediatrics & Adolescent Medicine, vol.154, issue.10, pp.997-1000, 2000.
DOI : 10.1001/archpedi.154.10.997

A. Takeyama, K. Hashimoto, M. Sato, R. Kawashima, Y. Kawasaki et al., Respiratory syncytial virus shedding by children hospitalized with lower respiratory tract infection, Journal of Medical Virology, vol.185, issue.6, pp.938-984, 2016.
DOI : 10.1086/339822

M. Thompson, T. Vodicka, P. Blair, D. Buckley, C. Heneghan et al., Duration of symptoms of respiratory tract infections in children: systematic review, BMJ, vol.347, issue.dec11 1, p.7027, 2013.
DOI : 10.1136/bmj.f7027

K. Ventre and A. Randolph, WITHDRAWN: Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children, Cochrane Database Syst Rev. 12 mai, issue.5, p.181, 2010.

M. Vergez, Assistance respiratoire dans la bronchiolite du nourrisson de moins de 3 mois : à propos d'une cohorte de 240 nourrissons, 2014.
URL : https://hal.archives-ouvertes.fr/dumas-01237512

E. Wang, R. Milner, L. Navas, and H. Maj, Observer Agreement for Respiratory Signs and Oximetry in Infants Hospitalized with Lower Respiratory Infections, American Review of Respiratory Disease, vol.145, issue.1, pp.106-115, 1992.
DOI : 10.1001/jama.1985.03360210063030