R. Klein, Hyperglycemia and microvascular and macrovascular disease in diabetes. Diabetes Care, Feb, vol.18, issue.2, pp.258-68, 1995.
DOI : 10.2337/diacare.18.2.258

R. Turner, H. Millns, H. Neil, I. Stratton, S. Manley et al., Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom prospective diabetes study (UKPDS: 23), BMJ, vol.316, issue.7134, pp.823-831, 1998.
DOI : 10.1136/bmj.316.7134.823

J. Stamler, O. Vaccaro, J. Neaton, and D. Wentworth, Diabetes, Other Risk Factors, and 12-Yr Cardiovascular Mortality for Men Screened in the Multiple Risk Factor Intervention Trial, Diabetes Care, vol.16, issue.2, pp.434-478, 1993.
DOI : 10.2337/diacare.16.2.434

K. Malmberg, S. Yusuf, H. Gerstein, J. Brown, F. Zhao et al., Impact of diabetes on longterm prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry. Circulation, pp.1014-1023, 2000.

S. Laing, A. Swerdlow, S. Slater, A. Burden, A. Morris et al., Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes, Diabetologia, vol.46, issue.6, 2003.
DOI : 10.1007/s00125-003-1116-6

P. Deedwania, M. Kosiborod, E. Barrett, A. Ceriello, W. Isley et al., Hyperglycemia and Acute Coronary Syndrome, Anesthesiology, vol.109, issue.1, pp.1610-1619, 2008.
DOI : 10.1097/ALN.0b013e31817dced3

Y. Groeneveld, H. Petri, J. Hermans, and M. Springer, Relationship between blood glucose level and mortality in Type 2 diabetes mellitus: a systematic review, Diabetic Medicine, vol.19, issue.1, pp.2-13, 1999.
DOI : 10.2337/diacare.19.7.726

J. Kuusisto, L. Mykkänen, K. Pyörälä, and M. Laakso, NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes, pp.960-967, 1994.
DOI : 10.2337/diabetes.43.8.960

I. Stratton, A. Adler, H. Neil, D. Matthews, S. Manley et al., Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study, BMJ, vol.321, issue.7258, pp.405-417, 2000.
DOI : 10.1136/bmj.321.7258.405

M. Hanefeld, E. Duetting, and P. Bramlage, Cardiac implications of hypoglycaemia in patients with diabetes ??? a systematic review, Cardiovascular Diabetology, vol.12, issue.1, p.135, 2013.
DOI : 10.1111/j.1753-0407.2011.00143.x

N. Yakubovich and H. Gerstein, Serious Cardiovascular Outcomes in Diabetes: The Role of Hypoglycemia, Circulation, vol.123, issue.3, pp.342-350, 2011.
DOI : 10.1161/CIRCULATIONAHA.110.948489

. Advance-collaborative-group, A. Patel, S. Macmahon, C. J. Neal, B. Billot et al., Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes, N Engl J Med, vol.358, issue.24, pp.2560-72, 2008.

W. Duckworth, C. Abraira, T. Moritz, D. Reda, N. Emanuele et al., Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes, New England Journal of Medicine, vol.360, issue.2, pp.129-168, 2009.
DOI : 10.1056/NEJMoa0808431

URL : https://doi.org/10.1016/j.jvs.2009.02.026

H. Gerstein, M. Riddle, D. Kendall, R. Cohen, R. Goland et al., Glycemia Treatment Strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial, The American Journal of Cardiology, vol.99, issue.12, pp.34-43, 2007.
DOI : 10.1016/j.amjcard.2007.03.004

M. Brownlee, Biochemistry and molecular cell biology of diabetic complications, Nature, vol.414, issue.6865, pp.813-833, 2001.
DOI : 10.1038/414813a

T. Goraya, C. Leibson, P. Palumbo, S. Weston, J. Killian et al., Coronary atherosclerosis in diabetes mellitus, Journal of the American College of Cardiology, vol.40, issue.5, pp.946-53, 2002.
DOI : 10.1016/S0735-1097(02)02065-X

URL : https://doi.org/10.1016/s0735-1097(02)02065-x

K. Iwakura, H. Ito, M. Ikushima, S. Kawano, A. Okamura et al., Association between hyperglycemia and the no-reflow phenomenon inpatients with acute myocardial infarction, Journal of the American College of Cardiology, vol.41, issue.1, pp.1-7, 2003.
DOI : 10.1016/S0735-1097(02)02626-8

A. Mather, A. Crean, N. Abidin, G. Worthy, S. Ball et al., Relationship of dysglycemia to acute myocardial infarct size and cardiovascular outcome as determined by cardiovascular magnetic resonance, Journal of Cardiovascular Magnetic Resonance, vol.12, issue.1, p.61, 2010.
DOI : 10.1186/1532-429X-12-61

J. Alegria, T. Miller, R. Gibbons, Q. Yi, and S. Yusuf, Infarct size, ejection fraction, and mortality in diabetic patients with acute myocardial infarction treated with thrombolytic therapy, American Heart Journal, vol.154, issue.4, pp.743-50, 2007.
DOI : 10.1016/j.ahj.2007.06.020

L. Landstedt-hallin, A. Englund, U. Adamson, and P. Lins, Increased QT dispersion during hypoglycaemia in patients with type 2 diabetes mellitus, Journal of Internal Medicine, vol.352, issue.3, pp.299-307, 1999.
DOI : 10.1007/BF00176778

URL : http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2796.1999.00528.x/pdf

G. Gill, A. Woodward, I. Casson, and P. Weston, Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes???the ???dead in bed??? syndrome revisited, Diabetologia, vol.24, issue.1, pp.42-47, 2009.
DOI : 10.1093/qjmed/hcm072

N. Wahab, E. Cowden, N. Pearce, M. Gardner, H. Merry et al., Is blood glucose an independent predictor of mortality in acute myocardial infarction in the thrombolytic era?, Journal of the American College of Cardiology, vol.40, issue.10, pp.1748-54, 2002.
DOI : 10.1016/S0735-1097(02)02483-X

J. Meier, S. Deifuss, A. Klamann, V. Launhardt, W. Schmiegel et al., Plasma Glucose at Hospital Admission and Previous Metabolic Control Determine Myocardial Infarct Size and Survival in Patients With and Without Type 2 Diabetes: The Langendreer Myocardial Infarction and Blood Glucose in Diabetic Patients Assessment (LAMBDA), Diabetes Care, vol.28, issue.10, 2005.
DOI : 10.2337/diacare.28.10.2551

S. Yang, Y. Zhou, D. Hu, X. Nie, Y. Liu et al., Association between admission hypoglycaemia and in-hospital and 3-year mortality in older patients with acute myocardial infarction, Heart, vol.96, issue.18, pp.1444-50, 2010.
DOI : 10.1136/hrt.2009.189316

A. Svensson, D. Mcguire, P. Abrahamsson, and M. Dellborg, Association between hyper- and hypoglycaemia and 2 year all-cause mortality risk in diabetic patients with acute coronary events, European Heart Journal, vol.26, issue.13, pp.1255-61, 2005.
DOI : 10.1093/eurheartj/ehi230

M. Kosiborod, S. Inzucchi, H. Krumholz, L. Xiao, P. Jones et al., Glucometrics in Patients Hospitalized With Acute Myocardial Infarction: Defining the Optimal Outcomes-Based Measure of Risk, Circulation, vol.117, issue.8, pp.1018-1045, 2008.
DOI : 10.1161/CIRCULATIONAHA.107.740498

L. Mellbin, K. Malmberg, A. Waldenstrom, H. Wedel, and L. Ryden, Prognostic implications of hypoglycaemic episodes during hospitalisation for myocardial infarction in patients with type 2 diabetes: a report from the DIGAMI 2 trial, Heart, vol.95, issue.9, pp.721-728, 2009.
DOI : 10.1136/hrt.2008.152835

E. Moghissi, M. Korytkowski, M. Dinardo, D. Einhorn, R. Hellman et al., American Association of Clinical Endocrinologists and American Diabetes Association Consensus Statement on Inpatient Glycemic Control. Diabetes Care, pp.1119-1150, 2009.

K. Nerenberg, A. Goyal, D. Xavier, A. Sigamani, J. Ng et al., Piloting a Novel Algorithm for Glucose Control in the Coronary Care Unit: The RECREATE (REsearching Coronary REduction by Appropriately Targeting Euglycemia) trial, Diabetes Care, vol.35, issue.1, pp.19-24, 2012.
DOI : 10.2337/dc11-0706

M. Kosiborod, S. Inzucchi, H. Krumholz, F. Masoudi, A. Goyal et al., Glucose Normalization and Outcomes in Patients With Acute Myocardial Infarction, Archives of Internal Medicine, vol.169, issue.5, p.438, 2009.
DOI : 10.1001/archinternmed.2008.593

F. Service, G. Molnar, J. Rosevear, E. Ackerman, L. Gatewood et al., Mean Amplitude of Glycemic Excursions, a Measure of Diabetic Instability, Diabetes, vol.19, issue.9, pp.644-55, 1970.
DOI : 10.2337/diab.19.9.644

J. Smith-palmer, M. Brändle, R. Trevisan, O. Federici, M. Liabat et al., Assessment of the association between glycemic variability and diabetes-related complications in type 1 and type 2 diabetes, Diabetes Research and Clinical Practice, vol.105, issue.3, pp.273-84, 2014.
DOI : 10.1016/j.diabres.2014.06.007

M. Brownlee and I. Hirsch, ???Independent Risk Factor for Diabetic Complications, JAMA, vol.295, issue.14, pp.1707-1715, 2006.
DOI : 10.1001/jama.295.14.1707

I. Hirsch, Glycemic Variability and Diabetes Complications: Does It Matter? Of Course It Does! Diabetes Care, pp.1610-1614, 2015.
DOI : 10.2337/dc14-2898

URL : http://care.diabetesjournals.org/content/diacare/38/8/1610.full.pdf

L. Monnier, E. Mas, C. Ginet, F. Michel, L. Villon et al., Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes, JAMA, vol.295, issue.14, p.1681, 2006.
DOI : 10.1001/jama.295.14.1681

K. Torimoto, Y. Okada, H. Mori, and Y. Tanaka, Relationship between fluctuations in glucose levels measured by continuous glucose monitoring and vascular endothelial dysfunction in type 2 diabetes mellitus, Cardiovascular Diabetology, vol.12, issue.1, p.1, 2013.
DOI : 10.2337/dc08-0545

K. Azuma, Repetitive Fluctuations in Blood Glucose Enhance Monocyte Adhesion to the Endothelium of Rat Thoracic Aorta, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.26, issue.10, pp.2275-80, 2006.
DOI : 10.1161/01.ATV.0000239488.05069.03

S. Siegelaar, F. Holleman, J. Hoekstra, and J. Devries, Glucose variability; does it matter? Endocr Rev, pp.171-82, 2010.
DOI : 10.1210/er.2009-0021

URL : https://academic.oup.com/edrv/article-pdf/31/2/171/10334616/edrv0171.pdf

T. Mita, A. Otsuka, K. Azuma, T. Uchida, T. Ogihara et al., Swings in blood glucose levels accelerate atherogenesis in apolipoprotein E-deficient mice, Biochemical and Biophysical Research Communications, vol.358, issue.3, pp.679-85, 2007.
DOI : 10.1016/j.bbrc.2007.04.118

P. Dandona, Minimizing Glycemic Fluctuations in Patients with Type 2 Diabetes: Approaches and Importance. Diabetes Technol Ther [Internet], 2017.
DOI : 10.1089/dia.2016.0372

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647495/pdf

S. Suh and J. Kim, Glycemic Variability: How Do We Measure It and Why Is It Important?, Diabetes & Metabolism Journal, vol.39, issue.4, p.273, 2015.
DOI : 10.4093/dmj.2015.39.4.273

URL : http://synapse.koreamed.org/Synapse/Data/PDFData/2004DMJ/dmj-39-273.pdf

J. Lachin, S. Genuth, D. Nathan, B. Zinman, B. Rutledge et al., Effect of Glycemic Exposure on the Risk of Microvascular Complications in the Diabetes Control and Complications Trial--Revisited, Diabetes, vol.57, issue.4, pp.995-1001, 2008.
DOI : 10.2337/db07-1618

X. Tang, S. Li, Y. Wang, M. Wang, Q. Yin et al., Glycemic variability evaluated by continuous glucose monitoring system is associated with the 10-y cardiovascular risk of diabetic patients with well-controlled HbA1c, Clinica Chimica Acta, vol.461, pp.146-50, 2016.
DOI : 10.1016/j.cca.2016.08.004

G. Su, S. Mi, H. Tao, Z. Li, H. Yang et al., Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes, Cardiovascular Diabetology, vol.10, issue.1, p.19, 2011.
DOI : 10.1253/circj.71.202

S. Kataoka, M. Gohbara, N. Iwahashi, K. Sakamaki, T. Nakachi et al., Glycemic Variability on Continuous Glucose Monitoring System Predicts Rapid Progression of Non-Culprit Lesions in Patients With Acute Coronary Syndrome, Circulation Journal, vol.79, issue.10, pp.2246-54, 2015.
DOI : 10.1253/circj.CJ-15-0496

M. Gohbara, K. Hibi, T. Mitsuhashi, N. Maejima, N. Iwahashi et al., Glycemic Variability on Continuous Glucose Monitoring System Correlates With Non-Culprit Vessel Coronary Plaque Vulnerability in Patients With First-Episode Acute Coronary Syndrome?????? Optical Coherence Tomography Study ???, Circulation Journal, vol.80, issue.1, pp.202-212, 2016.
DOI : 10.1253/circj.CJ-15-0790

I. Teraguchi, T. Imanishi, Y. Ozaki, T. Tanimoto, M. Orii et al., Impact of glucose fluctuation and monocyte subsets on coronary plaque rupture, Nutrition, Metabolism and Cardiovascular Diseases, vol.24, issue.3, pp.309-323, 2014.
DOI : 10.1016/j.numecd.2013.08.010

M. Gohbara, N. Iwahashi, S. Kataoka, Y. Hayakawa, K. Sakamaki et al., Glycemic Variability Determined by Continuous Glucose Monitoring System Predicts Left Ventricular Remodeling in Patients With a First ST-Segment Elevation Myocardial Infarction, Circulation Journal, vol.79, issue.5, pp.1092-1101, 2015.
DOI : 10.1253/circj.CJ-14-1226

S. Siegelaar, L. Kerr, S. Jacober, and J. Devries, A Decrease in Glucose Variability Does Not Reduce Cardiovascular Event Rates in Type 2 Diabetic Patients After Acute Myocardial Infarction: A reanalysis of the HEART2D study, Diabetes Care, vol.34, issue.4, pp.855-862, 2011.
DOI : 10.2337/dc10-1684

E. Kilpatrick, A. Rigby, and S. Atkin, For debate.Glucose variability and diabetes complication risk: we need to know the answer, Diabetic Medicine, vol.298, issue.8, pp.868-71, 2010.
DOI : 10.1111/j.1464-5491.2010.02929.x

K. Lipska, L. Venkitachalam, K. Gosch, B. Kovatchev, G. Van-den-berghe et al., Glucose Variability and Mortality in Patients Hospitalized With Acute Myocardial Infarction, Circulation: Cardiovascular Quality and Outcomes, vol.5, issue.4, pp.550-557, 2012.
DOI : 10.1161/CIRCOUTCOMES.111.963298

URL : http://circoutcomes.ahajournals.org/content/circcvoq/5/4/550.full.pdf

L. Mellbin, K. Malmberg, L. Rydén, H. Wedel, D. Vestberg et al., The relationship between glycaemic variability and cardiovascular complications in patients with acute myocardial infarction and type 2 diabetes: a report from the DIGAMI 2 trial, European Heart Journal, vol.34, issue.5, pp.374-383
DOI : 10.1093/eurheartj/ehs384

G. Su, S. Mi, H. Tao, Z. Li, H. Yang et al., Impact of Admission Glycemic Variability, Glucose, and Glycosylated Hemoglobin on Major Adverse Cardiac Events After Acute Myocardial Infarction. Diabetes Care, pp.1026-1058, 2013.

G. Su, S. Mi, Z. Li, H. Tao, H. Yang et al., Prognostic value of early in-hospital glycemic excursion in elderly patients with acute myocardial infarction, Cardiovascular Diabetology, vol.12, issue.1, p.33, 2013.
DOI : 10.2337/dc10-1684

X. Zhang, J. Lu, G. Shan, Z. Yang, and W. Yang, Association between glucose variability and adverse in-hospital outcomes for Chinese patients with acute coronary syndrome, Saudi Med J, vol.31, issue.10, pp.1146-51, 2010.

X. Wang, X. Zhao, T. Dorje, H. Yan, J. Qian et al., Glycemic variability predicts cardiovascular complications in acute myocardial infarction patients with type 2 diabetes mellitus, International Journal of Cardiology, vol.172, issue.2, pp.498-500, 2014.
DOI : 10.1016/j.ijcard.2014.01.015

J. Xia, J. Xu, B. Li, Z. Liu, H. Hao et al., Association between glycemic variability and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with acute coronary syndrome during 30-day follow-up, Clinica Chimica Acta, vol.466, pp.2017162-2017168
DOI : 10.1016/j.cca.2017.01.022

D. Rodbard, The Challenges of Measuring Glycemic Variability, Journal of Diabetes Science and Technology, vol.7, issue.3, pp.712-717, 2012.
DOI : 10.1089/dia.2011.0191

P. Baghurst, D. Rodbard, and F. Cameron, The Minimum Frequency of Glucose Measurements from Which Glycemic Variation Can Be Consistently Assessed, Journal of Diabetes Science and Technology, vol.3, issue.5, 2010.
DOI : 10.1177/193229680900300515

G. Zuanetti, R. Latini, A. Maggioni, L. Santoro, and M. Franzosi, Influence of diabetes on mortality in acute myocardial infarction: Data from the GISSI-2 study, Journal of the American College of Cardiology, vol.22, issue.7, 1993.
DOI : 10.1016/0735-1097(93)90758-S

J. Devries, Glucose Variability: Where It Is Important and How to Measure It. Diabetes, pp.1405-1413, 2013.

J. Bragd, U. Adamson, L. Bäcklund, P. Lins, E. Moberg et al., Can glycaemic variability, as calculated from blood glucose self-monitoring, predict the development of complications in type??1 diabetes over a decade?, Diabetes & Metabolism, vol.34, issue.6, pp.612-618, 2008.
DOI : 10.1016/j.diabet.2008.04.005

C. The and *. Investigators, Effect of Glucose-Insulin-Potassium Infusion on Mortality in Patients With Acute ST-Segment Elevation Myocardial Infarction: The CREATE-ECLA Randomized Controlled Trial, JAMA, vol.293, issue.4, p.437, 2005.

N. Cheung, V. Wong, and M. Mclean, The Hyperglycemia: Intensive Insulin Infusion In Infarction (HI-5) Study: A randomized controlled trial of insulin infusion therapy for myocardial infarction, Diabetes Care, vol.29, issue.4, pp.765-70, 2006.
DOI : 10.2337/diacare.29.04.06.dc05-1894

S. Frontoni, D. Bartolo, P. Avogaro, A. Bosi, E. Paolisso et al., Glucose variability: An emerging target for the treatment of diabetes mellitus, Diabetes Research and Clinical Practice, vol.102, issue.2, 2013.
DOI : 10.1016/j.diabres.2013.09.007

M. Rizzo, M. Barbieri, R. Marfella, and G. Paolisso, Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of dipeptidyl peptidase-IV inhibition, Diabetes Care, vol.35, issue.10, pp.2076-82, 2012.
DOI : 10.2337/dc12-0199

M. Barbieri, M. Rizzo, R. Marfella, V. Boccardi, A. Esposito et al., Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors, Atherosclerosis, vol.227, issue.2, pp.349-54
DOI : 10.1016/j.atherosclerosis.2012.12.018

C. Irace, R. Fiorentino, C. Carallo, F. Scavelli, and A. Gnasso, Exenatide Improves Glycemic Variability Assessed by Continuous Glucose Monitoring in Subjects with Type 2 Diabetes, Diabetes Technology & Therapeutics, vol.13, issue.12, pp.1261-1264, 2011.
DOI : 10.1089/dia.2011.0096

H. Bajaj, K. Venn, C. Ye, A. Patrick, S. Kalra et al., Lowest Glucose Variability and Hypoglycemia Are Observed With the Combination of a GLP-1 Receptor Agonist and Basal Insulin (VARIATION Study), Diabetes Care, vol.40, issue.2, pp.194-200, 2017.
DOI : 10.2337/dc16-1582

A. El-laboudi, I. Godsland, D. Johnston, and N. Oliver, Measures of Glycemic Variability in Type 1 Diabetes and the Effect of Real-Time Continuous Glucose Monitoring, Diabetes Technology & Therapeutics, vol.18, issue.12, pp.806-818, 2016.
DOI : 10.1089/dia.2016.0146

S. Marso, G. Daniels, K. Brown-frandsen, P. Kristensen, J. Mann et al., Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes, Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes, pp.311-333, 2016.
DOI : 10.1056/NEJMoa1603827