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Master Thesis

Étude de prévalence des hypominéralisations molaires et incisives au sein d'un échantillon d'enfants basques : influence(s) génétique et/ou épigénétique ?

Abstract : Molar-incisor hypomineralization (MIH) represents enamel structural abnormalities affecting at least one of the first permanent molars and often the permanent incisors. The prevalence of MIH is variable over the countries, ranging from 3 to 40%. Our study aims to explore the main putative etiological factors and to evaluate the MIH prevalence in the Basque population which is known for its cultural and biological particularities. Our retrospective study included 516 children aged from 7 to 11 living in the Basque Country area. Individuals were considered as Basques if they had typical Basque surnames and their four grand-parents of Basque origin. Parents filled out a questionnaire and presented their child health record. Enamel defects were described by a single operator using localization, color and tissue loss criteria. We didn’t evidence any statistical association between the studied factors and MIH occurrence. Nevertheless, Basques present a border line risk to develop MIH (OR=1,3; IC=95=0,87-2,04). The respective roles of genetic and epigenetic factors warrant to be further investigated.
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https://dumas.ccsd.cnrs.fr/dumas-01671720
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Submitted on : Friday, December 22, 2017 - 3:14:15 PM
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Elena Cedarry. Étude de prévalence des hypominéralisations molaires et incisives au sein d'un échantillon d'enfants basques : influence(s) génétique et/ou épigénétique ?. Chirurgie. 2017. ⟨dumas-01671720⟩

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