P. Bochud, M. Bonten, O. Marchetti, and C. T. , Antimicrobial therapy for patients with severe sepsis and septic shock: An evidence-based review, Critical Care Medicine, vol.32, issue.Supplement, pp.495-512, 2004.
DOI : 10.1097/01.CCM.0000143118.41100.14

X. Nassif, Physiopathologie des m??ningites purulentes, M??decine et Maladies Infectieuses, vol.26, pp.1016-1037, 1996.
DOI : 10.1016/S0399-077X(96)80013-8

D. Van-de-beek, J. Drake, and A. Tunkel, Nosocomial Bacterial Meningitis, New England Journal of Medicine, vol.362, issue.2, pp.146-54, 2010.
DOI : 10.1056/NEJMra0804573

A. Tunkel and W. Scheld, Pathogenesis and pathophysiology of bacterial meningitis., Clinical Microbiology Reviews, vol.6, issue.2, pp.118-154, 1993.
DOI : 10.1128/CMR.6.2.118

D. Chadwick, Viral meningitis, British Medical Bulletin, vol.75, issue.1, pp.1-14, 2005.
DOI : 10.1093/bmb/ldh057

M. Weisfelt, D. Van-de-beek, L. Spanjaard, and J. De-gans, Nosocomial bacterial meningitis in adults: a prospective series of 50 cases, Journal of Hospital Infection, vol.66, issue.1, pp.71-79, 2007.
DOI : 10.1016/j.jhin.2007.02.017

B. Rudinsky, A. Ondrusova, P. Kisac, M. Sramka, P. Beno et al., National 14 years survey of 171 cases nosocomial meningitis in children and comparison of two periods 1993, Neuro Endocrinol Lett. juin, vol.28, issue.2, pp.11-15, 1998.

M. Tsai, C. Lu, C. Huang, Y. Chuang, N. Tsai et al., Bacterial Meningitis in Young Adults in Southern Taiwan: Clinical Characteristics and Therapeutic Outcomes, Infection, vol.34, issue.1, pp.2-8, 2006.
DOI : 10.1007/s15010-006-4144-6

A. Korinek, T. Baugnon, J. Golmard, R. Van-effenterre, P. Coriat et al., Risk factors for adult nosocomial meningitis after craniotomy, role of antibiotuc prophylaxis, Neurosurgery. 1 juill, vol.59, issue.1, pp.126-159, 2006.

S. Muttaiyah, S. Ritchie, A. Upton, and S. Roberts, Clinical parameters do not predict infection in patients with external ventricular drains: a retrospective observational study of daily cerebrospinal fluid analysis, Journal of Medical Microbiology, vol.57, issue.2, pp.207-216, 2008.
DOI : 10.1099/jmm.0.47518-0

L. Walti, A. Conen, J. Coward, G. Jost, and A. Trampuz, Characteristics of infections associated with external ventricular drains of cerebrospinal fluid, Journal of Infection, vol.66, issue.5, pp.424-455, 2013.
DOI : 10.1016/j.jinf.2012.12.010

S. Muñoz-gómez, E. Wirkowski, and B. Cunha, Post craniotomy extra-ventricular drain (EVD) associated nosocomial meningitis: CSF diagnostic criteria, Heart & Lung: The Journal of Acute and Critical Care, vol.44, issue.2, pp.158-60, 2015.
DOI : 10.1016/j.hrtlng.2015.01.003

S. Giulieri, C. Chapuis-taillard, K. Jaton, A. Cometta, C. Chuard et al., CSF lactate for accurate diagnosis of community-acquired bacterial meningitis, European Journal of Clinical Microbiology & Infectious Diseases, vol.88, issue.1, pp.2049-55, 2015.
DOI : 10.4269/ajtmh.2012.12-0447

X. Xiao, Y. Zhang, L. Zhang, P. Kang, and J. N. , The diagnostic value of cerebrospinal fluid lactate for post-neurosurgical bacterial meningitis: a meta-analysis, BMC Infectious Diseases, vol.64, issue.3A, p.483, 2016.
DOI : 10.1590/S0004-282X2006000400012

B. Pfausler, R. Beer, K. Engelhardt, G. Kemmler, I. Mohsenipour et al., Cell index ? a new parameter for the early diagnosis of ventriculostomy (external ventricular drainage)-related ventriculitis in patients with intraventricular hemorrhage?, Acta Neurochirurgica, vol.146, issue.5, pp.477-81, 2004.
DOI : 10.1007/s00701-004-0258-8

V. Zarrouk, V. Leflon-guibout, J. Vellin, D. Bouccara, A. Redondo et al., I-08 ??valuation de la place de la PCR ARN 16S dans le diagnostic des m??ningites post op??ratoires en chirurgie intracr??nienne, Médecine et Maladies Infectieuses, p.49, 2009.
DOI : 10.1016/S0399-077X(09)74422-1

A. Renvoisé, Applicabilité de la PCR « universelle » 16S comme outil d'identification et de détection bactérienne en laboratoire hospitalier de bactériologie, Thèse de doctorat, 2012.

P. Tattevin, M. Revest, and S. Lavoue, M??ningites et m??ningoenc??phalites aseptiques, R??animation, vol.17, issue.7, pp.639-50, 2008.
DOI : 10.1016/j.reaurg.2008.07.006

J. Albanèse, M. Léone, B. Bruguerolle, M. Ayem, B. Lacarelle et al., Cerebrospinal Fluid Penetration and Pharmacokinetics of Vancomycin Administered by Continuous Infusion to Mechanically Ventilated Patients in an Intensive Care Unit, Antimicrobial Agents and Chemotherapy, vol.44, issue.5, pp.1356-1364, 2000.
DOI : 10.1128/AAC.44.5.1356-1358.2000

F. Van-bambeke and P. Tulkens, Pharmacodynamie des antibiotiques dans le LCR??: principes et cons??quences (facteurs pr??dictifs d???efficacit??), M??decine et Maladies Infectieuses, vol.39, issue.7-8, pp.483-92, 2009.
DOI : 10.1016/j.medmal.2009.02.038

H. Portier, M. Armengaud, B. Becq-giraudon, J. Bousser, J. Desbordes et al., Treatment with a cefotaxime-fosfomycin combination of staphylococcal or enterobacterial meningitis in adults, Presse Medicale Paris Fr, pp.2161-2167, 1983.

A. Bergis, Etude préliminaire à la réalisation d'un protocole d'antibiothérapie probabiliste : profil bactériologique de l'unité de réanimation neurochirurgicale du, 2014.

M. Wysocki, F. Delatour, F. Faurisson, A. Rauss, Y. Pean et al., Continuous versus Intermittent Infusion of Vancomycin in Severe Staphylococcal Infections: Prospective Multicenter Randomized Study, Antimicrobial Agents and Chemotherapy, vol.45, issue.9, pp.2460-2467, 2001.
DOI : 10.1128/AAC.45.9.2460-2467.2001

E. Masson, Ajustement de la posologie de la vancomycine administrée en perfusion continue chez des patients de réanimation [Internet]

R. Mounier, D. Lobo, A. Hulin, B. Nebbad, F. Cook et al., Is First-Line Vancomycin Still the Best Option to Treat Staphylococcus Health Care-Associated Meningitis? World Neurosurg, mars, vol.99, pp.812-813, 2017.

D. Lonsdale, A. Udy, J. Roberts, and . J. Lipman, Antibacterial therapeutic drug monitoring in cerebrospinal fluid: difficulty in achieving adequate drug concentrations, Journal of Neurosurgery, vol.118, issue.2, pp.297-301, 2013.
DOI : 10.3171/2012.10.JNS12883

URL : http://thejns.org/doi/pdf/10.3171/2012.10.JNS12883

P. Villani, M. Regazzi, F. Marubbi, P. Viale, L. Pagani et al., Cerebrospinal Fluid Linezolid Concentrations in Postneurosurgical Central Nervous System Infections, Antimicrobial Agents and Chemotherapy, vol.46, issue.3, pp.936-943, 2002.
DOI : 10.1128/AAC.46.3.936-937.2002

URL : http://aac.asm.org/content/46/3/936.full.pdf

O. Sipahi, S. Bardak, T. Turhan, A. B. Pullukcu, H. Ruksen et al., Linezolid in the treatment of methicillin-resistant staphylococcal post-neurosurgical meningitis: A series of 17 cases, Scandinavian Journal of Infectious Diseases, vol.41, issue.10, pp.757-64, 2011.
DOI : 10.1111/j.1468-1331.2008.02193.x

A. Kessler and A. Kourtis, Treatment of Meningitis Caused by Methicillin-Resistant Staphylococcus aureus with Linezolid, Infection, vol.36, issue.4, pp.271-275, 2007.
DOI : 10.1007/s15010-007-6211-z

W. Krueger, B. Kottler, B. Will, A. Heininger, H. Guggenberger et al., Treatment of Meningitis Due to Methicillin-Resistant Staphylococcus epidermidis with Linezolid, Journal of Clinical Microbiology, vol.42, issue.2, pp.929-961, 2004.
DOI : 10.1128/JCM.42.2.929-932.2004

U. Blassmann, A. Roehr, O. Frey, C. Vetter-kerkhoff, N. Thon et al., Cerebrospinal fluid penetration of meropenem in neurocritical care patients with proven or suspected ventriculitis: a prospective observational study, Critical Care, vol.32, issue.12, p.343, 2016.
DOI : 10.1186/s13054-016-1523-y

Y. Zhang, J. Zhang, Y. Chen, J. Yu, G. Cao et al., Evaluation of Meropenem Penetration into Cerebrospinal Fluid in Patients with Meningitis After Neurosurgery, World Neurosurgery, vol.98, pp.525-556, 2017.
DOI : 10.1016/j.wneu.2016.11.040

H. Zhao, J. Gu, J. Lyu, D. Liu, Y. Wang et al., Pharmacokinetic and Pharmacodynamic Efficacies of Continuous versus Intermittent Administration of Meropenem in Patients with Severe Sepsis and Septic Shock: A Prospective Randomized Pilot Study, Chin Med J (Engl), vol.130, issue.10, pp.1139-1184, 2017.

. Société-française-d-'anesthésie-et-de-réanimation, Antibioprophylaxie en chirurgie et médecine interventionnelle (patients adultes) Actualisation 2010. Ann Fr Anesth Réanimation, févr, vol.30, issue.2, pp.168-90, 2011.

M. Leverstein-van-hall, T. Hopmans, J. Van-der-sprenkel, H. Blok, W. Van-der-mark et al., A bundle approach to reduce the incidence of external ventricular and lumbar drain-related infections, Journal of Neurosurgery, vol.112, issue.2, pp.345-53, 2009.
DOI : 10.3171/2009.6.JNS09223

A. Sonabend, Y. Korenfeld, C. Crisman, N. Badjatia, S. Mayer et al., Prevention of Ventriculostomy-Related Infections With Prophylactic Antibiotics and Antibiotic-Coated External Ventricular Drains: A Systematic Review, Neurosurgery, vol.179, issue.8, pp.996-1005, 2011.
DOI : 10.1503/cmaj.071812

H. Richards, H. Seeley, and J. Pickard, Efficacy of antibiotic-impregnated shunt catheters in reducing shunt infection: data from the United Kingdom Shunt Registry, Journal of Neurosurgery: Pediatrics, vol.4, issue.4, pp.389-93, 2009.
DOI : 10.3171/2009.4.PEDS09210

A. Konstantelias, K. Vardakas, K. Polyzos, G. Tansarli, and M. Falagas, Antimicrobial-impregnated and -coated shunt catheters for prevention of infections in patients with hydrocephalus: a systematic review and meta-analysis, Journal of Neurosurgery, vol.122, issue.5, pp.1096-112, 2015.
DOI : 10.3171/2014.12.JNS14908

K. Holloway, T. Barnes, S. Choi, R. Bullock, L. Marshall et al., Ventriculostomy infections: the effect of monitoring duration and catheter exchange in 584 patients, Journal of Neurosurgery, vol.85, issue.3, pp.419-443, 1996.
DOI : 10.3171/jns.1996.85.3.0419

A. Korinek, R. M. Boch, A. Rivera, A. Bels, D. Puybasset et al., Prevention of external ventricular drain ? related ventriculitis, Acta Neurochirurgica, vol.147, issue.1, pp.39-46, 2005.
DOI : 10.1007/s00701-004-0416-z

Y. Ren, X. Liu, C. You, Y. Zhang, L. Du et al., Efficacy of Closed Continuous Lumbar Drainage on the Treatment of Postcraniotomy Meningitis: A Retrospective Analysis of 1062 Cases, World Neurosurgery, vol.106, 2017.
DOI : 10.1016/j.wneu.2017.07.073

Y. Abulhasan, H. Jehani, M. Valiquette, A. Mcmanus, M. Dolan-cake et al., Lumbar Drainage for the Treatment of Severe Bacterial Meningitis, Neurocritical Care, vol.28, issue.5, pp.199-205, 2013.
DOI : 10.3109/00365549609037939