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. Barre, 30% d'insuffisance respiratoire d'origine neuromusculaire survient chez ces malades de façon imprévisible. L'identification de facteurs prédictifs permettrait d'améliorer leurs prises en charge. Le but de notre étude était d'identifier des facteurs cliniques et biologiques associés au recours à la ventilation mécanique

. Lors, épidémie de Zika en Martinique, étude prospective de cohorte des patients atteints de GBS répondant aux niveaux de certitude diagnostique 1 ou 2 de la Brighton Collaboration associés à une infection à ZIKV prouvée biologiquement, Les données cliniques et biologiques étaient comparées entre patients nécessitant une ventilation mécanique et patients non ventilés

. La-rapidité-d, installation du déficit moteur et sa profondeur sont des éléments cliniques témoignant de la gravité du SGB. De façon plus spécifique au SGB consécutif à une infection à ZIKV, la mise en évidence urinaire de ZIKV par RT-PCR semble être un critère biologique de gravité devant alerter les cliniciens et motiver une surveillance en unité de soins intensifs