M. Alizadeh, M. Bernard, B. Danic, C. Dauriac, B. Birebent et al., Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction, Blood, vol.99, issue.12, pp.4618-4625, 2002.
DOI : 10.1182/blood.V99.12.4618

P. Bader, J. Beck, A. Frey, P. G. Schlegel, H. Hebarth et al., Serial and quantitative analysis of mixed hematopoietic chimerism by PCR in patients with acute leukemias allows the prediction of relapse after allogeneic BMT, Bone Marrow Transplantation, vol.21, issue.5, pp.487-495, 1998.
DOI : 10.1038/sj.bmt.1701119

P. Bader, W. Hölle, T. Klingebiel, R. Handgretinger, N. Benda et al., Mixed hematopoietic chimerism after allogeneic bone marrow transplantation: the impact of quantitative PCR analysis for prediction of relapse and graft rejection in children, Bone Marrow Transplantation, vol.19, issue.7, pp.697-702, 1997.
DOI : 10.1038/sj.bmt.1700721

P. Bader, H. Kreyenberg, W. Hoelle, G. Dueckers, R. Handgretinger et al., Increasing Mixed Chimerism Is an Important Prognostic Factor for Unfavorable Outcome in Children With Acute Lymphoblastic Leukemia After Allogeneic Stem-Cell Transplantation: Possible Role For Pre-Emptive Immunotherapy?, Journal of Clinical Oncology, vol.22, issue.9, pp.1696-1705, 2004.
DOI : 10.1200/JCO.2004.05.198

P. Bader, H. Kreyenberg, W. Hoelle, G. Dueckers, B. Kremens et al., Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective, Bone Marrow Transplantation, vol.77, issue.Suppl. 2, pp.815-821, 2004.
DOI : 10.1016/S0198-8859(96)00290-X

J. N. Barker, C. Byam, and A. Scaradavou, How I treat: the selection and acquisition of unrelated cord blood grafts, Blood, vol.117, issue.8, pp.2332-2339, 2011.
DOI : 10.1182/blood-2010-04-280966

M. Barrios, A. Jiménez-velasco, J. Román-gómez, M. E. Madrigal, J. A. Castillejo et al., Chimerism status is a useful predictor of relapse after allogeneic stem cell transplantation for acute leukemia, Haematologica, vol.88, pp.801-810, 2003.

S. Berglund, L. Blanc, K. Remberger, M. Gertow, J. Uzunel et al., Factors With an Impact on Chimerism Development and Long-Term Survival After Umbilical Cord Blood Transplantation, Transplantation Journal, vol.94, issue.10, pp.1066-1074, 2012.
DOI : 10.1097/TP.0b013e31826c39b2

J. J. Boelens, M. Aldenhoven, D. Purtill, A. Ruggeri, T. Defor et al., Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning, Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning, pp.3981-3987, 2013.
DOI : 10.1182/blood-2012-09-455238

M. Eapen, P. Rubinstein, M. Zhang, C. Stevens, J. Kurtzberg et al., Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study, The Lancet, vol.369, issue.9577, pp.1947-1954, 2007.
DOI : 10.1016/S0140-6736(07)60915-5

J. P. Fine, Regression modeling of competing crude failure probabilities, Biostatistics, vol.2, issue.1, pp.85-97, 2001.
DOI : 10.1093/biostatistics/2.1.85

E. Gluckman, V. Rocha, W. Arcese, G. Michel, G. Sanz et al., Factors associated with outcomes of unrelated cord blood transplant: Guidelines for donor choice, Experimental Hematology, vol.32, issue.4, pp.397-407, 2004.
DOI : 10.1016/j.exphem.2004.01.002

T. A. Gooley, W. Leisenring, J. Crowley, and B. E. Storer, Estimation of failure probabilities in the presence of competing risks: new representations of old estimators, Statistics in Medicine, vol.1, issue.6, pp.695-706, 1999.
DOI : 10.1016/0360-3016(94)90416-2

R. Lamba, E. Abella, D. Kukuruga, J. Klein, S. Savasan et al., Mixed hematopoietic chimerism at day 90 following allogenic myeloablative stem cell transplantation is a predictor of relapse and survival, Leukemia, vol.10, issue.10, pp.1681-1686, 2004.
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K. J. Livak and T. D. Schmittgen, Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2???????CT Method, Methods, vol.25, issue.4, pp.402-408, 2001.
DOI : 10.1006/meth.2001.1262

F. Locatelli, V. Rocha, C. Chastang, W. Arcese, G. Michel et al., Factors associated with outcome after cord blood transplantation in children with acute leukemia. Eurocord-Cord Blood Transplant Group, Blood, vol.93, pp.3662-3671, 1999.

M. Mohty, O. Avinens, C. Faucher, P. Viens, D. Blaise et al., Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation, Haematologica, vol.92, issue.7, pp.1004-1006, 2007.
DOI : 10.3324/haematol.10971

F. Moscardó, J. Sanz, L. Senent, S. Cantero, J. De-la-rubia et al., Impact of hematopoietic chimerism at day +14 on engraftment after unrelated donor umbilical cord blood transplantation for hematologic malignancies, Haematologica, vol.94, issue.6, pp.827-832, 2009.
DOI : 10.3324/haematol.2008.000935

E. Nikolousis, S. Robinson, S. Nagra, C. Brookes, F. Kinsella et al., Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant, Leukemia Research, vol.37, issue.5, pp.561-565, 2013.
DOI : 10.1016/j.leukres.2013.01.010

M. Park, K. N. Koh, J. J. Seo, and H. J. Im, Clinical implications of chimerism after allogeneic hematopoietic stem cell transplantation in children with non-malignant diseases, The Korean Journal of Hematology, vol.46, issue.4, pp.258-264, 2011.
DOI : 10.5045/kjh.2011.46.4.258

V. K. Prasad, A. Mendizabal, S. H. Parikh, P. Szabolcs, T. A. Driscoll et al., Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes, Blood, vol.112, issue.7, pp.2979-2989, 2008.
DOI : 10.1182/blood-2008-03-140830

V. Rocha, J. Cornish, E. L. Sievers, A. Filipovich, F. Locatelli et al., Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia, Blood, vol.97, issue.10, pp.2962-2971, 2001.
DOI : 10.1182/blood.V97.10.2962

J. Rupa-matysek, K. Lewandowski, W. Nowak, K. Sawi?ski, L. Gil et al., Correlation Between the Kinetics of CD3+ Chimerism and the Incidence of Graft-Versus-Host Disease in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation, Transplantation Proceedings, vol.43, issue.5, pp.1915-1923, 2011.
DOI : 10.1016/j.transproceed.2011.02.011

B. Saito, T. Fukuda, H. Yokoyama, S. Kurosawa, T. Takahashi et al., Impact of T Cell Chimerism on Clinical Outcome in 117 Patients Who Underwent Allogeneic Stem Cell Transplantation with a Busulfan-Containing Reduced-Intensity Conditioning Regimen, Biology of Blood and Marrow Transplantation, vol.14, issue.10, pp.1148-1155, 2008.
DOI : 10.1016/j.bbmt.2008.07.013

A. Stikvoort, J. Gertow, M. Sundin, M. Remberger, J. Mattsson et al., Chimerism Patterns of Long-Term Stable Mixed Chimeras Posthematopoietic Stem Cell Transplantation in Patients with Nonmalignant Diseases: Follow-Up of Long-Term Stable Mixed Chimerism Patients, Biology of Blood and Marrow Transplantation, vol.19, issue.5, pp.838-844, 2013.
DOI : 10.1016/j.bbmt.2013.02.015

P. Svenberg, J. Mattsson, O. Ringdén, and M. Uzunel, Allogeneic hematopoietic SCT in patients with non-malignant diseases and importance of chimerism, Bone Marrow Transplantation, vol.91, issue.11, pp.757-763, 2009.
DOI : 10.1046/j.1365-2141.2000.01851.x

M. Verneris, L. Turcotte, Q. Cao, M. Macmillan, J. Miller et al., Increased relapse associated with mixed donor-donor chimerism following double umbilical cord blood transplantation, Blood, vol.120, 2012.

J. E. Wagner, J. N. Barker, T. E. Defor, K. S. Baker, B. R. Blazar et al., Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival, Blood, vol.100, pp.1611-1618, 2002.

±. Moyenne and . Sem-médiane, ) Diagnostic : Pathologies Malignes, p.25

±. Moyenne and . Sem-médiane, 10) Devenir post greffe GvHDa

M. Alizadeh, M. Bernard, B. Danic, C. Dauriac, B. Birebent et al., Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction, Blood, vol.99, issue.12, pp.4618-4625, 2002.
DOI : 10.1182/blood.V99.12.4618

P. Bader, J. Beck, A. Frey, P. G. Schlegel, H. Hebarth et al., Serial and quantitative analysis of mixed hematopoietic chimerism by PCR in patients with acute leukemias allows the prediction of relapse after allogeneic BMT, Bone Marrow Transplantation, vol.21, issue.5, pp.487-495, 1998.
DOI : 10.1038/sj.bmt.1701119

P. Bader, W. Hölle, T. Klingebiel, R. Handgretinger, N. Benda et al., Mixed hematopoietic chimerism after allogeneic bone marrow transplantation: the impact of quantitative PCR analysis for prediction of relapse and graft rejection in children, Bone Marrow Transplantation, vol.19, issue.7, pp.697-702, 1997.
DOI : 10.1038/sj.bmt.1700721

P. Bader, H. Kreyenberg, W. Hoelle, G. Dueckers, R. Handgretinger et al., Increasing Mixed Chimerism Is an Important Prognostic Factor for Unfavorable Outcome in Children With Acute Lymphoblastic Leukemia After Allogeneic Stem-Cell Transplantation: Possible Role For Pre-Emptive Immunotherapy?, Journal of Clinical Oncology, vol.22, issue.9, pp.1696-1705, 2004.
DOI : 10.1200/JCO.2004.05.198

P. Bader, H. Kreyenberg, W. Hoelle, G. Dueckers, B. Kremens et al., Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective, Bone Marrow Transplantation, vol.77, issue.Suppl. 2, pp.815-821, 2004.
DOI : 10.1016/S0198-8859(96)00290-X

J. N. Barker, C. Byam, and A. Scaradavou, How I treat: the selection and acquisition of unrelated cord blood grafts, Blood, vol.117, issue.8, pp.2332-2339, 2011.
DOI : 10.1182/blood-2010-04-280966

M. Barrios, A. Jiménez-velasco, J. Román-gómez, M. E. Madrigal, J. A. Castillejo et al., Chimerism status is a useful predictor of relapse after allogeneic stem cell transplantation for acute leukemia, Haematologica, vol.88, pp.801-810, 2003.

S. Berglund, L. Blanc, K. Remberger, M. Gertow, J. Uzunel et al., Factors with an impact 80, 2012.

J. J. Boelens, M. Aldenhoven, D. Purtill, A. Ruggeri, T. Defor et al., Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning, Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning, pp.3981-3987, 2013.
DOI : 10.1182/blood-2012-09-455238

M. Eapen, P. Rubinstein, M. Zhang, C. Stevens, J. Kurtzberg et al., Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study, The Lancet, vol.369, issue.9577, pp.1947-1954, 2007.
DOI : 10.1016/S0140-6736(07)60915-5

J. P. Fine, Regression modeling of competing crude failure probabilities, Biostatistics, vol.2, issue.1, pp.85-97, 2001.
DOI : 10.1093/biostatistics/2.1.85

E. Gluckman, V. Rocha, W. Arcese, G. Michel, G. Sanz et al., Factors associated with outcomes of unrelated cord blood transplant: Guidelines for donor choice, Experimental Hematology, vol.32, issue.4, pp.397-407, 2004.
DOI : 10.1016/j.exphem.2004.01.002

T. A. Gooley, W. Leisenring, J. Crowley, and B. E. Storer, Estimation of failure probabilities in the presence of competing risks: new representations of old estimators, Statistics in Medicine, vol.1, issue.6, pp.695-706, 1999.
DOI : 10.1016/0360-3016(94)90416-2

K. J. Livak and T. D. Schmittgen, Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2???????CT Method, Methods, vol.25, issue.4, pp.402-408, 2001.
DOI : 10.1006/meth.2001.1262

F. Locatelli, V. Rocha, C. Chastang, W. Arcese, G. Michel et al., Factors associated with outcome after cord blood transplantation in children with acute leukemia. Eurocord-Cord Blood Transplant Group, Blood, vol.93, pp.3662-3671, 1999.

M. Mohty, O. Avinens, C. Faucher, P. Viens, D. Blaise et al., Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation, Haematologica, vol.92, issue.7, pp.1004-1006, 2007.
DOI : 10.3324/haematol.10971

F. Moscardó, J. Sanz, L. Senent, S. Cantero, J. De-la-rubia et al., Impact of hematopoietic chimerism at day +14 on engraftment after unrelated donor umbilical cord blood transplantation for hematologic malignancies, Haematologica, vol.94, issue.6, pp.827-832, 2009.
DOI : 10.3324/haematol.2008.000935

E. Nikolousis, S. Robinson, S. Nagra, C. Brookes, F. Kinsella et al., Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant, Leukemia Research, vol.37, issue.5, pp.561-565, 2013.
DOI : 10.1016/j.leukres.2013.01.010

M. Park, K. N. Koh, J. J. Seo, and H. J. Im, Clinical implications of chimerism after allogeneic hematopoietic stem cell transplantation in children with non-malignant diseases, The Korean Journal of Hematology, vol.46, issue.4, pp.258-264, 2011.
DOI : 10.5045/kjh.2011.46.4.258

V. K. Prasad, A. Mendizabal, S. H. Parikh, P. Szabolcs, T. A. Driscoll et al., Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes, Blood, vol.112, issue.7, pp.2979-2989, 2008.
DOI : 10.1182/blood-2008-03-140830

V. Rocha, J. Cornish, E. L. Sievers, A. Filipovich, F. Locatelli et al., Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia, Blood, vol.97, issue.10, pp.2962-2971, 2001.
DOI : 10.1182/blood.V97.10.2962

J. Rupa-matysek, K. Lewandowski, W. Nowak, K. Sawi?ski, L. Gil et al., Correlation Between the Kinetics of CD3+ Chimerism and the Incidence of Graft-Versus-Host Disease in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation, Transplantation Proceedings, vol.43, issue.5, pp.1915-1923, 2011.
DOI : 10.1016/j.transproceed.2011.02.011

B. Saito, T. Fukuda, H. Yokoyama, S. Kurosawa, T. Takahashi et al., Impact of T Cell Chimerism on Clinical Outcome in 117 Patients Who Underwent Allogeneic Stem Cell Transplantation with a Busulfan-Containing Reduced-Intensity Conditioning Regimen, Biology of Blood and Marrow Transplantation, vol.14, issue.10, pp.1148-1155, 2008.
DOI : 10.1016/j.bbmt.2008.07.013

A. Stikvoort, J. Gertow, M. Sundin, M. Remberger, J. Mattsson et al., Chimerism Patterns of Long-Term Stable Mixed Chimeras Posthematopoietic Stem Cell Transplantation in Patients with Nonmalignant Diseases: Follow-Up of Long-Term Stable Mixed Chimerism Patients, Biology of Blood and Marrow Transplantation, vol.19, issue.5, pp.838-844, 2013.
DOI : 10.1016/j.bbmt.2013.02.015

P. Svenberg, J. Mattsson, O. Ringdén, and M. Uzunel, Allogeneic hematopoietic SCT in patients with non-malignant diseases and importance of chimerism, Bone Marrow Transplantation, vol.91, issue.11, pp.757-763, 2009.
DOI : 10.1046/j.1365-2141.2000.01851.x

M. Verneris, L. Turcotte, Q. Cao, M. Macmillan, J. Miller et al., Increased relapse associated with mixed donor-donor chimerism following double umbilical cord blood transplantation, Blood, 2012.

J. E. Wagner, J. N. Barker, T. E. Defor, K. S. Baker, B. R. Blazar et al., Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival, Blood, vol.100, pp.1611-1618, 2002.