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Master Thesis

Prise en charge des hydrocéphalies en pédiatrie : revue de la littérature et étude rétrospective au sein du CHU de Saint Pierre à La Réunion

Abstract : Introduction: the literature review for the management of pediatric hydrocephalus shows that there is currently little agreement on the “best” treatment and evidence-based guidelines are lacking. We aimed to describe characteristics, management and outcome of pediatric hydrocephalus in infants cared for in the neonatal and pediatric intensive care unit of Saint Pierre university hospital over 4 years. Patients and methods: we performed a retrospective study based on medical records. All children referred for hydrocephalus and all preterm infants cared for post-hemorrhagic hydrocephalus from 1 January 2014 to 31 December 2017 were eligible. Primary outcome measure was for preterm babies: “discharged alive without hydrocephalus needing treatment” and for children ‘’no failure of the first shunt placement”. Results: in total 19 preterm infants and 69 children were included. The primary outcome was observed in 15 preterm infants (78%) and lumbar punctures avoided the need for shunt placement in 46% of post-hemorrhagic hydrocephalus. Among children, the primary outcome was observed in 41 patients (59%); the complication rate was 47% (32% mechanical and 15% infectious complications). Conclusion: repeated lumbar punctures were beneficial for avoiding the need for shunt placement in our cohort cared for post-hemorrhagic hydrocephalus and this result needs to be explored in future, prospective investigations. The rate of mechanical and infectious complications in children treated for hydrocephalus was high in this population and our results emphasize the importance of discerning safe and effective treatments for facilities caring for pediatric hydrocephalus.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01806292
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Marine Scaon-Tanguy. Prise en charge des hydrocéphalies en pédiatrie : revue de la littérature et étude rétrospective au sein du CHU de Saint Pierre à La Réunion. Médecine humaine et pathologie. 2018. ⟨dumas-01806292⟩

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