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Master Thesis

Impact de l’épidémie de Zika en Guadeloupe sur la demande d’interruption volontaire de grossesse au CHU de Pointe-à-Pitre

Abstract : Background: After many epidemics of Zika worldwide, several studies have evaluated the impact of this virosis and have revealed serious obstetric complications. This has led to a significant increase of abortion requests in some Latin American countries. Zika virus appears in Guadeloupe in January 2016, and the official epidemic is declared from April 25 to September 25, 2016. Purpose: We evaluated the impact of the Zika virus on the abortion request in the Abortion Department of the University Hospital Center of Pointe-à-Pitre (CHUPPA), during the period of the epidemic. Method: We performed a retrospective, monocentric, observational, descriptive and analytical study. The main objective was to estimate the number of abortions requested because of Zika during the period of the epidemic (weeks 17 to 38 of 2016), in the Abortion Department of CHUPPA. We also did a descriptive study of the sociodemographic and clinical data of our patients. Finally, we compared the number of abortions in 2016 to the number of abortions during other years (2011 to 2015 and 2017), during weeks 17 to 38 and during the other weeks of the year. We collected all abortion files in the department during the outbreak (439). Results: Only 8 women (1,8% of the population studied), requested an abortion because of Zika over the period studied. Sociodemographic and clinical data (age, origin, place of birth and residence, work and family status, substance use, history of miscarriage or abortion) did not significantly influence the request for abortion. Finally, we found no significant difference between the number of abortions requested in 2016 and the number of abortions during other years, whether in weeks 17 to 38 or the rest of the year. Discussion: Our study has not shown any significant results, but it has the merit of being the first on this subject in the French West Indies. It is subject to many biases because it is retrospective and monocentric ; in case of a new epidemic, it would be interesting to organize a prospective study.
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Master Thesis
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Submitted on : Wednesday, October 24, 2018 - 4:01:55 PM
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Juliette Perazza. Impact de l’épidémie de Zika en Guadeloupe sur la demande d’interruption volontaire de grossesse au CHU de Pointe-à-Pitre. Médecine humaine et pathologie. 2018. ⟨dumas-01903773⟩

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