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Master Thesis

Maladies neuromusculaires dégénératives et grossesse : étude descriptive des complications de la grossesse et des modes d’accouchements chez les femmes enceintes atteintes de maladies neuromusculaires dégénératives à l’HCE de Grenoble

Abstract : Objectives : To determine the complications of the pregnancy, the influence of the pregnancy on the disability and the means of delivery and anaesthesia in women affected by degenerative neuromuscular diseases. Materials and methods : This is a descriptive epidemiological study, retrospective, realised at the “Hopital Couple Enfants” of Grenoble. Patients were enrolled during a period from January 2005 to May 2017. Data were collected from the computing medical and obstetrical records and concerned the medical and obstetrical maternal data and the fetal and neonatal data. Results : The forced expiratory volume in 1 second in late pregnancy is on average of 54.33% and 4 pregnancies have required a non-invasive ventilation. Six out of 16 pregnancies presented a urinary tract infection and 3 of them a premature delivery threat, with a lot of hospitalisations in high-risk pregnancy department. A caesarean was realised in 9 out of 16 pregnancies. In case of a conduct of vaginal delivery, this was respected in only 50% cases. An epidural analgesia was done in 8 out of 16 deliveries and a general anaesthesia for 3 deliveries. Six out of 17 children were born prematurely and 6 children required resuscitation cares. In 3 pregnancies, children were affected by myotonic dystrophy. Conclusion : This study shows the importance of the complications of pregnancy in women affected by degenerative neuromuscular disease and the necessity of knowing them better to improve the obstetric and psychosocial follow-up of these women.
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https://dumas.ccsd.cnrs.fr/dumas-01908552
Contributor : Jean-Hugues Morneau <>
Submitted on : Tuesday, October 30, 2018 - 11:39:58 AM
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Léa Moresco. Maladies neuromusculaires dégénératives et grossesse : étude descriptive des complications de la grossesse et des modes d’accouchements chez les femmes enceintes atteintes de maladies neuromusculaires dégénératives à l’HCE de Grenoble. Gynécologie et obstétrique. 2018. ⟨dumas-01908552⟩

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