C. P. Gyawali, A. J. Bredenoord, and J. L. Conklin, Evaluation of esophageal motor function in clinical practice: Esophageal motor testing in clinical practice, Neurogastroenterol Motil, vol.25, issue.2, pp.99-133, 2013.

B. Coffin and S. Roman, Esophageal motility disorders. Hépato-Gastro Oncol Dig, vol.20, issue.1, 2013.

F. Zerbib and S. Roman, Les nouvelles explorations fonctionelles oesophagiennes, pp.47-56, 2011.

P. J. Kahrilas, A. J. Bredenoord, and M. Fox, Expert consensus document: Advances in the management of oesophageal motility disorders in the era of high-resolution manometry: a focus on achalasia syndromes, Nat Rev Gastroenterol Hepatol, vol.14, issue.11, pp.677-88, 2017.

S. Roman, L. Huot, and F. Zerbib, High-Resolution Manometry Improves the Diagnosis of Esophageal Motility Disorders in Patients With Dysphagia: A Randomized Multicenter Study, Am J Gastroenterol, vol.111, issue.3, pp.372-80, 2016.
URL : https://hal.archives-ouvertes.fr/hal-02296591

M. R. Fox and A. J. Bredenoord, Oesophageal high-resolution manometry: moving from research into clinical practice, Gut, vol.57, issue.3, pp.405-428, 2008.

J. E. Pandolfino and P. J. Kahrilas, American Gastroenterological Association. American Gastroenterological Association medical position statement: Clinical use of esophageal manometry, Gastroenterology, vol.128, issue.1, pp.207-215, 2005.

S. Roman, S. Bruney-des-varannes, and G. Cargill, Manométrie oesophagienne de haute résolution avec analyse topographique des pressions oesophagiennes : Conseils pour la pratique et adaptation française de la classification de Chicago, Hépato Gastro, vol.19, p.316, 2012.

V. Guinard-samuel, Quelles sont les indications justifiées de la manométrie oesophagienne en pédiatrie ?, Réal Pédiatriques, issue.207, 2017.

S. Nurko, Motility Disorders in Children, Pediatr Clin North Am, vol.64, issue.3, pp.593-612, 2017.

R. Rosen, J. M. Garza, and N. Tipnis, An ANMS-NASPGHAN consensus document on esophageal and antroduodenal manometry in children, Neurogastroenterol Motil, 2017.

F. Edeani, A. Malik, and A. Kaul, Characterization of Esophageal Motility Disorders in Children Presenting With Dysphagia Using High-Resolution Manometry, Curr Gastroenterol Rep, vol.19, issue.3, p.13, 2017.

M. Jain, M. Srinivas, and P. Bawane, Does Chicago Classification address Symptom Correlation with High-resolution Esophageal Manometry? Ozkan H, éditeur, Euroasian J Hepato-Gastroenterol, vol.7, issue.2, pp.122-127, 2017.

N. Rommel, T. I. Omari, and M. Selleslagh, High-resolution manometry combined with 22 impedance measurements discriminates the cause of dysphagia in children, Eur J Pediatr, vol.174, issue.12, pp.1629-1666, 2015.

R. Hankard, V. Colomb, and H. Piloquet, Dépister la dénutrition de l'enfant en pratique courante, Arch Pédiatrie, vol.19, issue.10, pp.1110-1117, 2012.

B. T. Johnston, Oesophageal dysphagia: a stepwise approach to diagnosis and management, Lancet Gastroenterol Hepatol, vol.2, issue.8, pp.604-613, 2017.

R. Rosen, Y. Vandenplas, and M. Singendonk, Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN), J Pediatr Gastroenterol Nutr, vol.1, 2018.

P. Sherman, E. Hassall, and U. Fagundes-neto, Consensus factuel international sur la définition du reflux gastro-oesophagien pathologique en pédiatrie, Arch Pédiatrie, vol.17, issue.11, pp.1586-93, 2010.

F. Gottrand and J. Sarles, De l'intérêt de distinguer le reflux gastro-oesophagien (RGO) physiologique du RGO maladie, Arch Pédiatrie, vol.17, issue.11, pp.1505-1511, 2010.

P. J. Kahrilas, A. J. Bredenoord, and M. Fox, The Chicago Classification of esophageal motility disorders, Neurogastroenterol Motil, vol.27, issue.2, pp.160-74, 2015.

M. Singendonk, M. J. Smits, and I. E. Heijting, Inter-and intrarater reliability of the Chicago Classification in pediatric high-resolution esophageal manometry recordings, Neurogastroenterol Motil, vol.27, issue.2, pp.269-76, 2015.

M. Singendonk, S. Kritas, and C. Cock, Applying the Chicago Classification criteria of esophageal motility to a pediatric cohort: effects of patient age and size, Neurogastroenterol Motil, vol.26, issue.9, pp.1333-1374, 2014.

M. Mello and C. P. Gyawali, Esophageal Manometry in Gastroesophageal Reflux Disease, Gastroenterol Clin North Am, vol.43, issue.1, pp.69-87, 2014.

N. Rommel and T. Omari, Abnormal Pharyngoesophageal Function in Infants and Young Children: Diagnosis With High-resolution Manometry, J Pediatr Gastroenterol Nutr, vol.52, pp.29-30, 2011.

S. Viola, J. M. Goutet, and G. Audry, Le mégaoesophage de l'enfant : profil clinique et évolution à long terme, Arch Pédiatrie, vol.12, issue.4, pp.391-397, 2005.

S. Tong, K. Mallitt, and U. Krishnan, Evaluation of Gastroesophageal Reflux by Combined Multichannel Intraluminal Impedance and pH Monitoring and Esophageal Motility Patterns in Children with Esophageal Atresia, Eur J Pediatr Surg, vol.26, issue.04, pp.322-353, 2015.

M. Singendonk, R. Rosen, and J. Oors, Intra-and interrater reliability of the Chicago Classification of achalasia subtypes in pediatric high-resolution esophageal manometry (HRM) recordings, Neurogastroenterol Motil, 2017.

K. Nikaki, J. Ooi, and D. Sifrim, Chicago Classification of Esophageal Motility Disorders: Applications and Limits in Adults and Pediatric Patients with Esophageal Symptoms, Curr Gastroenterol Rep, vol.18, issue.11, 2016.

L. Michaud, M. Lamblin, and C. Carpentier, Reflux gastrooesophagien et troubles de la motricité oesophagienne chez des nourrissons porteurs d'une hyper-réflectivité vagale ayant présenté un malaise grave, Arch Pédiatrie, vol.4, issue.2, pp.133-142, 1997.

E. Devouge, L. Michaud, and M. D. Lamblin, Primary esophageal motor disorders in childhood, genuine achalasia excluded, Arch Pediatr Organe Off Soc Francaise Pediatr, vol.9, issue.7, pp.664-70, 2002.

C. Faure, R. Grunder, and F. Dysmotility, Esophageal Atresia: Pathophysiology, Characterization, and Treatment. Front Pediatr, 2017.

R. N. Pedersen, S. Markøw, and S. Kruse-andersen, Esophageal Atresia: Gastroesophageal functional follow-up in 5-15year old children, J Pediatr Surg, vol.48, issue.12, pp.2487-95, 2013.

C. Lemoine, A. Aspirot, L. Henaff, and G. , Characterization of Esophageal Motility Following Esophageal Atresia Repair Using High-Resolution Esophageal Manometry, J Pediatr Gastroenterol Nutr, vol.56, issue.6, pp.609-623, 2013.

M. Rayyan, T. Omari, and K. Allegaert, PP-10 Characterization of esophageal motility in infants born with congenital diaphragmatic hernia using high resolution manometry, J Pediatr Gastroenterol Nutr, vol.61, issue.4, p.524, 2015.

Z. W. Hu, Z. G. Wang, and J. M. Wu, Relationship between the severity of reflux esophagitis and the esophageal motility features on high resolution manometry, Zhonghua Yi Xue Za Zhi, vol.97, issue.42, pp.3306-3317, 2017.

R. Turco, D. Ummarino, and E. Miele, PP-8 esophageal high resolution manometry in neurologicallly impaired children and gastro-oesophageal reflux disease, J Pediatr Gastroenterol Nutr, vol.61, issue.4, p.523, 2015.

H. Goldani, A. Staiano, and O. Borrelli, Pediatric Esophageal High-Resolution Manometry: Utility of a Standardized Protocol and Size-Adjusted Pressure Topography Parameters, Am J Gastroenterol, vol.105, issue.2, pp.460-467, 2010.

A. Staiano, G. Boccia, and E. Miele, Segmental characteristics of oesophageal peristalsis in paediatric patients, Neurogastroenterol Motil, vol.0, issue.0, p.40122001, 2007.

C. Scheerens, J. Tack, and N. Rommel, Buspirone, a new drug for the management of patients with ineffective esophageal motility? United, Eur Gastroenterol J, vol.3, issue.3, pp.261-266, 2015.

S. Samo, Ineffective Esophageal Motility Progressing into Distal Esophageal Spasm and Then Type III Achalasia, ACG Case Rep J, vol.3, issue.4, 2016.

J. Kim, J. K. Hwang, and W. Seok-choi, Ineffective Esophageal Motility: Is It a Transient Manometric Finding? Kor, J Neurogastroenterol Motil, vol.14, issue.2, pp.103-110, 2008.

T. Arif, Q. Masood, and J. Singh, Assessment of esophageal involvement in systemic sclerosis and morphea (localized scleroderma) by clinical, endoscopic, manometric and pH metric features: a prospective comparative hospital based study, BMC Gastroenterol, vol.15, issue.1, 2015.

J. Wipff, R. Coriat, and M. Masciocchi, Outcomes of Barrett's oesophagus related to systemic sclerosis: a 3-year EULAR Scleroderma Trials and Research prospective follow-up study, Rheumatology, vol.50, issue.8, pp.1440-1444, 2011.

C. P. Gyawali, S. Roman, and A. J. Bredenoord, Classification of esophageal motor findings in gastro-esophageal reflux disease: Conclusions from an international consensus group, Neurogastroenterol Motil, vol.29, issue.12, p.13104, 2017.

R. Rosen, Y. Vandenplas, and M. Singendonk, Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN), J Pediatr Gastroenterol Nutr, vol.1, 2018.

L. Michaud, Démarche diagnostique devant une dysphagie d'origine oesophagienne chez l'enfant, Arch Pédiatrie, vol.18, issue.5, pp.156-163, 2011.
DOI : 10.1016/s0929-693x(11)71015-6

C. Vigier, S. Henno, and S. Willot, L'oesophagite à éosinophiles chez l'enfant : évaluation des pratiques, Arch Pédiatrie, vol.24, issue.4, pp.327-362, 2017.

C. P. Gyawali, A. J. Bredenoord, and J. L. Conklin, Evaluation of esophageal motor function in clinical practice: Esophageal motor testing in clinical practice, Neurogastroenterol Motil, vol.25, issue.2, pp.99-133, 2013.

B. Coffin and S. Roman, Esophageal motility disorders, Hépato-Gastro Oncol Dig, vol.20, issue.1, 2013.

F. Zerbib and S. Roman, Les nouvelles explorations fonctionelles oesophagiennes, pp.47-56, 2011.
DOI : 10.1007/978-2-8178-0237-4_6

P. J. Kahrilas, A. J. Bredenoord, and M. Fox, Expert consensus document: Advances in the management of oesophageal motility disorders in the era of high-resolution manometry: a focus on achalasia syndromes, Nat Rev Gastroenterol Hepatol, vol.14, issue.11, pp.677-88, 2017.

S. Roman, L. Huot, and F. Zerbib, High-Resolution Manometry Improves the Diagnosis of Esophageal Motility Disorders in Patients With Dysphagia: A Randomized Multicenter Study, Am J Gastroenterol, vol.111, issue.3, pp.372-80, 2016.

M. R. Fox and A. J. Bredenoord, Oesophageal high-resolution manometry: moving from research into clinical practice, Gut, vol.57, issue.3, pp.405-428, 2008.
DOI : 10.1136/gut.2007.127993

URL : https://gut.bmj.com/content/gutjnl/57/3/405.full.pdf

J. E. Pandolfino and P. J. Kahrilas, American Gastroenterological Association. American Gastroenterological Association medical position statement: Clinical use of esophageal manometry, Gastroenterology, vol.128, issue.1, pp.207-215, 2005.

S. Roman, S. Bruney-des-varannes, and G. Cargill, Manométrie oesophagienne de haute résolution avec analyse topographique des pressions oesophagiennes : Conseils pour la pratique et adaptation française de la classification de Chicago, Hépato Gastro, vol.19, p.316, 2012.

V. Guinard-samuel, Quelles sont les indications justifiées de la manométrie oesophagienne en pédiatrie ?, Réal Pédiatriques, issue.207, 2017.

S. Nurko, Motility Disorders in Children, Pediatr Clin North Am, vol.64, issue.3, pp.593-612, 2017.
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R. Rosen, J. M. Garza, and N. Tipnis, An ANMS-NASPGHAN consensus document on esophageal and antroduodenal manometry in children, Neurogastroenterol Motil, 2017.
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URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823717

F. Edeani, A. Malik, and A. Kaul, Characterization of Esophageal Motility Disorders in Children Presenting With Dysphagia Using High-Resolution Manometry, Curr Gastroenterol Rep, vol.19, issue.3, p.13, 2017.

M. Jain, M. Srinivas, and P. Bawane, Does Chicago Classification address Symptom Correlation with High-resolution Esophageal Manometry? Ozkan H, éditeur, Euroasian J Hepato-Gastroenterol, vol.7, issue.2, pp.122-127, 2017.
DOI : 10.5005/jp-journals-10018-1231

URL : http://europepmc.org/articles/pmc5670253?pdf=render

N. Rommel, T. I. Omari, and M. Selleslagh, High-resolution manometry combined with impedance measurements discriminates the cause of dysphagia in children, Eur J Pediatr, vol.174, issue.12, pp.1629-1666, 2015.

P. J. Kahrilas, A. J. Bredenoord, and M. Fox, The Chicago Classification of esophageal motility disorders, Neurogastroenterol Motil, vol.27, issue.2, pp.160-74, 2015.
DOI : 10.1007/978-1-4471-5484-6_3

M. Singendonk, M. J. Smits, and I. E. Heijting, Inter-and intrarater reliability of the Chicago Classification in pediatric high-resolution esophageal manometry recordings, Neurogastroenterol Motil, vol.27, issue.2, pp.269-76, 2015.

M. Singendonk, S. Kritas, and C. Cock, Applying the Chicago Classification criteria of esophageal motility to a pediatric cohort: effects of patient age and size, Neurogastroenterol Motil, vol.26, issue.9, pp.1333-1374, 2014.

M. Mello and C. P. Gyawali, Esophageal Manometry in Gastroesophageal Reflux Disease, Gastroenterol Clin North Am, vol.43, issue.1, pp.69-87, 2014.

N. Rommel and T. Omari, Abnormal Pharyngoesophageal Function in Infants and Young Children: Diagnosis With High-resolution Manometry, J Pediatr Gastroenterol Nutr, vol.52, pp.29-30, 2011.
DOI : 10.1097/mpg.0b013e318213a4b8

S. Viola, J. M. Goutet, and G. Audry, Le mégaoesophage de l'enfant : profil clinique et évolution à long terme, Arch Pédiatrie, vol.12, issue.4, pp.391-397, 2005.
DOI : 10.1016/j.arcped.2004.10.023

S. Tong, K. Mallitt, and U. Krishnan, Evaluation of Gastroesophageal Reflux by Combined Multichannel Intraluminal Impedance and pH Monitoring and Esophageal Motility Patterns in Children with Esophageal Atresia, Eur J Pediatr Surg, vol.26, issue.04, pp.322-353, 2015.

M. Singendonk, R. Rosen, and J. Oors, Intra-and interrater reliability of the Chicago Classification of achalasia subtypes in pediatric high-resolution esophageal manometry (HRM) recordings, Neurogastroenterol Motil, 2017.

K. Nikaki, J. Ooi, and D. Sifrim, Chicago Classification of Esophageal Motility Disorders: Applications and Limits in Adults and Pediatric Patients with Esophageal Symptoms, Curr Gastroenterol Rep, vol.18, issue.11, 2016.

L. Michaud, M. Lamblin, and C. Carpentier, Reflux gastrooesophagien et troubles de la motricité oesophagienne chez des nourrissons porteurs d'une hyper-réflectivité vagale ayant présenté un malaise grave, Arch Pédiatrie, vol.4, issue.2, pp.133-142, 1997.
DOI : 10.1016/s0929-693x(97)86155-6

E. Devouge, L. Michaud, and M. D. Lamblin, Primary esophageal motor disorders in childhood, genuine achalasia excluded, Arch Pediatr Organe Off Soc Francaise Pediatr, vol.9, issue.7, pp.664-70, 2002.

C. Faure, R. Grunder, and F. Dysmotility, Esophageal Atresia: Pathophysiology, Characterization, and Treatment. Front Pediatr, 2017.

R. N. Pedersen, S. Markøw, and S. Kruse-andersen, Esophageal Atresia: Gastroesophageal functional follow-up in 5-15year old children, J Pediatr Surg, vol.48, issue.12, pp.2487-95, 2013.
DOI : 10.1016/j.jpedsurg.2013.07.019

C. Lemoine, A. Aspirot, L. Henaff, and G. , Characterization of Esophageal Motility Following Esophageal Atresia Repair Using High-Resolution Esophageal Manometry, J Pediatr Gastroenterol Nutr, vol.56, issue.6, pp.609-623, 2013.

M. Rayyan, T. Omari, and K. Allegaert, PP-10 Characterization of esophageal motility in infants born with congenital diaphragmatic hernia using high resolution manometry, J Pediatr Gastroenterol Nutr, vol.61, issue.4, p.524, 2015.

Z. W. Hu, Z. G. Wang, and J. M. Wu, Relationship between the severity of reflux esophagitis and the esophageal motility features on high resolution manometry, Zhonghua Yi Xue Za Zhi, vol.97, issue.42, pp.3306-3317, 2017.

R. Turco, D. Ummarino, and E. Miele, PP-8 Esophageal high resolution manometry in neurologicallly impaired children and gastro-oesophageal reflux disease, J Pediatr Gastroenterol Nutr, vol.61, issue.4, p.523, 2015.
DOI : 10.1097/01.mpg.0000472236.37108.30

URL : https://pdfs.journals.lww.com/jpgn/2015/10000/PP_8_ESOPHAGEAL_HIGH_RESOLUTION_MANOMETRY_IN.58.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1519474866021;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21Csk0OpQi3YbjEMdSoz2UhVybFqQxA7lKwSUlA502zQZr96TQRwhVlocEp/sJ586aVbcBFlltKNKo+tbuMfL73hiPqJliudqs17cHeLcLbV/CqjlP3IO0jGHlHQtJWcICDdAyGJMnpi6RlbEJaRheGeh5z5uvqz3FLHgPKVXJzd9dgA82ss8wECSuWSg1aZkOyAYyReIXBzCZw+OxwS7T0=;hash|hjIc914kWPy9YhiCJQHMaQ==

H. Goldani, A. Staiano, and O. Borrelli, Pediatric Esophageal High-Resolution Manometry: Utility of a Standardized Protocol and Size-Adjusted Pressure Topography Parameters, Am J Gastroenterol, vol.105, issue.2, pp.460-467, 2010.
DOI : 10.1038/ajg.2009.656

A. Staiano, G. Boccia, and E. Miele, Segmental characteristics of oesophageal peristalsis in paediatric patients, Neurogastroenterol Motil, vol.0, issue.0, p.071121040122001, 2007.
DOI : 10.1111/j.1365-2982.2007.00999.x

C. Scheerens, J. Tack, and N. Rommel, Buspirone, a new drug for the management of patients with ineffective esophageal motility? United, Eur Gastroenterol J, vol.3, issue.3, pp.261-266, 2015.

S. Samo, Ineffective Esophageal Motility Progressing into Distal Esophageal Spasm and Then Type III Achalasia, ACG Case Rep J, vol.3, issue.4, 2016.

J. Kim, J. K. Hwang, and W. Seok-choi, Ineffective Esophageal Motility: Is It a Transient Manometric Finding? Kor, J Neurogastroenterol Motil, vol.14, issue.2, pp.103-110, 2008.

T. Arif, Q. Masood, and J. Singh, Assessment of esophageal involvement in systemic sclerosis and morphea (localized scleroderma) by clinical, endoscopic, manometric and pH metric features: a prospective comparative hospital based study, BMC Gastroenterol, vol.15, issue.1, 2015.

J. Wipff, R. Coriat, and M. Masciocchi, Outcomes of Barrett's oesophagus related to systemic sclerosis: a 3-year EULAR Scleroderma Trials and Research prospective followup study, Rheumatology, vol.50, issue.8, pp.1440-1444, 2011.

C. P. Gyawali, S. Roman, and A. J. Bredenoord, Classification of esophageal motor findings in gastro-esophageal reflux disease: Conclusions from an international consensus group, Neurogastroenterol Motil, vol.29, issue.12, p.13104, 2017.

R. Rosen, Y. Vandenplas, and M. Singendonk, Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN), J Pediatr Gastroenterol Nutr, vol.1, p.45, 2018.

L. Michaud, Démarche diagnostique devant une dysphagie d'origine oesophagienne chez l'enfant, Arch Pédiatrie, vol.18, issue.5, pp.156-163, 2011.

C. Vigier, S. Henno, and S. Willot, L'oesophagite à éosinophiles chez l'enfant : évaluation des pratiques, Arch Pédiatrie, vol.24, issue.4, pp.327-362, 2017.

R. Hankard, V. Colomb, and H. Piloquet, Dépister la dénutrition de l'enfant en pratique courante, Arch Pédiatrie, vol.19, issue.10, pp.1110-1117, 2012.

B. T. Johnston, Oesophageal dysphagia: a stepwise approach to diagnosis and management, Lancet Gastroenterol Hepatol, vol.2, issue.8, pp.604-613, 2017.

R. Rosen, Y. Vandenplas, and M. Singendonk, Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN), J Pediatr Gastroenterol Nutr, vol.1, 2018.

P. Sherman, E. Hassall, and U. Fagundes-neto, Consensus factuel international sur la définition du reflux gastro-oesophagien pathologique en pédiatrie, Arch Pédiatrie, vol.17, issue.11, pp.1586-93, 2010.

F. Gottrand and J. Sarles, De l'intérêt de distinguer le reflux gastro-oesophagien (RGO) physiologique du RGO maladie, Arch Pédiatrie, vol.17, issue.11, p.20, 2010.

, Esophagogastric junction LES: Lower esophageal sphincter UES: Upper esophageal sphincter Journal of Pediatric Gastroenterology & Nutrition Correlation between clinical signs and high-resolution manometry data in children.-Manuscript DraftManuscript Number: Full Title: Correlation between clinical signs and high-resolution manometry data in children. Article Type: Original Article Section/Category: Gastroenterology (Europe) Keywords: Esophageal motility disorders; Children; Chicago Classification, GERD: Gastro-esophageal reflux disease CIPO: Chronic intestinal pseudo-obstruction HRM: High-resolution manometry EGJ

, HRM) is the gold standard for esophageal motility disorders diagnosis. However, clinical signs associated to these disorders are non-specific and it is difficult correlate clinical signs with HRM data. The main objective of our study was to assess the positive predictive value (PPV) and negative predictive value (NPV) of each clinical sign, as well as their sensitivity and specificity in the diagnosis of esophageal motility disorders. METHODS: This is a bi-centric retrospective cohort study based on HRM data collected between, Corresponding Author Secondary Information: Corresponding Author's Institution: Hopital de la Timone Corresponding Author's Secondary Institution: First Author: Marine JUZAUD First Author Secondary Information: Order of Authors: Marine Juzaud Secondary Information: Manuscript Region of Origin: FRANCE Abstract: OBJECTIVES: High-resolution manometry, 2012.