C. Martí-henneberg and B. Vizmanos, The duration of puberty in girls is related to the timing of its onset, J Pediatr, vol.131, issue.4, pp.618-639, 1997.

G. Teilmann, C. B. Pedersen, T. K. Jensen, N. E. Skakkebaek, and A. Juul, Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries, Pediatrics, vol.116, issue.6, pp.1323-1331, 2005.

E. R. González, For puberty that comes too soon, new treatment highly effective, JAMA, vol.248, issue.10, pp.1149-51, 1155.

T. Wu, P. Mendola, and G. M. Buck, Ethnic differences in the presence of secondary sex characteristics and menarche among US girls: the Third National Health and Nutrition Examination Survey, Pediatrics, vol.110, issue.4, pp.752-759, 1988.

S. S. Sun, C. M. Schubert, W. C. Chumlea, A. F. Roche, H. E. Kulin et al., National estimates of the timing of sexual maturation and racial differences among US children, Pediatrics, vol.110, issue.5, pp.911-920, 2002.

A. Parent, G. Teilmann, A. Juul, N. E. Skakkebaek, J. Toppari et al., The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration, Endocr Rev, vol.24, issue.5, pp.668-93, 2003.

G. Teilmann, C. B. Pedersen, N. E. Skakkebaek, and T. K. Jensen, Increased risk of precocious puberty in internationally adopted children in Denmark, Pediatrics, vol.118, issue.2, pp.391-399, 2006.

R. L. Matchock and E. J. Susman, Family composition and menarcheal age: anti-inbreeding strategies, Am J Hum Biol Off J Hum Biol Counc, vol.18, issue.4, pp.481-91, 2006.

W. A. Sonis, F. Comite, J. Blue, O. H. Pescovitz, C. W. Rahn et al., Behavior problems and social competence in girls with true precocious puberty, J Pediatr, vol.106, issue.1, pp.156-60, 1985.

P. Michaud, J. Suris, and A. Deppen, Gender-related psychological and behavioural correlates of pubertal timing in a national sample of Swiss adolescents, Mol Cell Endocrinol, pp.172-180, 2006.

J. C. Carel, M. Roger, S. Ispas, F. Tondu, N. Lahlou et al., Final height after longterm treatment with triptorelin slow release for central precocious puberty: importance of statural growth after interruption of treatment. French study group of Decapeptyl in Precocious Puberty, J Clin Endocrinol Metab, vol.84, issue.6, pp.1973-1981, 1999.

S. Heger, M. Müller, M. Ranke, H. Schwarz, F. Waldhauser et al., Long-term GnRH agonist treatment for female central precocious puberty does not impair reproductive function, Mol Cell Endocrinol, pp.217-237, 2006.

S. Fischbein, Intra-pair similarity in physical growth of opposite-sex twin pairs during puberty, Ann Hum Biol, vol.10, issue.2, pp.135-180, 1983.

M. Sklad, The rate of growth and maturing of twins, Acta Genet Med Gemellol (Roma), vol.26, issue.3-4, pp.221-258, 1977.

L. De-vries, A. Kauschansky, M. Shohat, and M. Phillip, Familial central precocious puberty suggests autosomal dominant inheritance, J Clin Endocrinol Metab, vol.89, issue.4, pp.1794-800, 2004.

M. G. Teles, S. Bianco, V. N. Brito, E. B. Trarbach, W. Kuohung et al., A GPR54Activating Mutation in a Patient with Central Precocious Puberty, N Engl J Med, vol.358, issue.7, pp.709-724, 2008.

L. G. Silveira, S. D. Noel, A. P. Silveira-neto, A. P. Abreu, V. N. Brito et al., Mutations of the KISS1 gene in disorders of puberty, J Clin Endocrinol Metab, vol.95, issue.5, pp.2276-80, 2010.

D. B. Macedo, A. P. Abreu, A. Reis, L. R. Montenegro, A. Dauber et al., Central precocious puberty that appears to be sporadic caused by paternally inherited mutations in the imprinted gene makorin ring finger 3, J Clin Endocrinol Metab, vol.99, issue.6, pp.1097-1103, 2014.

S. Leka-emiri, E. Louizou, M. Kambouris, G. Chrousos, N. De-roux et al., Absence of GPR54 and TACR3 mutations in sporadic cases of idiopathic central precocious puberty, Horm Res Paediatr, vol.81, issue.3, pp.177-81, 2014.

A. P. Abreu, A. Dauber, D. B. Macedo, S. D. Noel, V. N. Brito et al., Central precocious puberty caused by mutations in the imprinted gene MKRN3, N Engl J Med, vol.368, issue.26, pp.2467-75, 2013.

A. P. Abreu, D. B. Macedo, V. N. Brito, U. B. Kaiser, and A. C. Latronico, A new pathway in the control of the initiation of puberty: the MKRN3 gene, J Mol Endocrinol, vol.54, issue.3, pp.131-139, 2015.

T. Varimo, L. Dunkel, K. Vaaralahti, P. J. Miettinen, M. Hero et al., Circulating makorin ring finger protein 3 levels decline in boys before the clinical onset of puberty, Eur J Endocrinol, vol.174, issue.6, pp.785-90, 2016.

M. T. Jong, T. A. Gray, J. Y. Glenn, C. C. Saitoh, S. Driscoll et al., A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the PraderWilli syndrome critical region, Hum Mol Genet, vol.8, issue.5, pp.783-93, 1999.

N. Settas, C. Dacou-voutetakis, M. Karantza, C. Kanaka-gantenbein, G. P. Chrousos et al., Central precocious puberty in a girl and early puberty in her brother caused by a novel mutation in the MKRN3 gene, J Clin Endocrinol Metab, vol.99, issue.4, pp.647-651, 2014.

F. Schreiner, B. Gohlke, M. Hamm, E. Korsch, and J. Woelfle, MKRN3 mutations in familial central precocious puberty, Horm Res Paediatr, vol.82, issue.2, pp.122-128, 2014.

L. De-vries, G. Gat-yablonski, N. Dror, A. Singer, and M. Phillip, A novel MKRN3 missense mutation causing familial precocious puberty, Hum Reprod Oxf Engl, vol.29, issue.12, pp.2838-2881, 2014.

M. F. Stecchini, D. B. Macedo, A. Reis, A. P. Abreu, A. C. Moreira et al., Time Course of Central Precocious Puberty Development Caused by an MKRN3 Gene Mutation: A Prismatic Case, Horm Res Paediatr, vol.86, issue.2, pp.126-156, 2016.

J. Känsäkoski, T. Raivio, A. Juul, and J. Tommiska, A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty, Pediatr Res, vol.78, issue.6, pp.709-720, 2015.

A. Grandone, G. Cantelmi, G. Cirillo, P. Marzuillo, C. Luongo et al., A case of familial central precocious puberty caused by a novel mutation in the makorin RING finger protein 3 gene, BMC Endocr Disord, vol.15, p.60, 2015.

M. S. Dimitrova-mladenova, E. M. Stefanova, M. Glushkova, A. P. Todorova, T. Todorov et al., Males with Paternally Inherited MKRN3 Mutations May Be Asymptomatic, J Pediatr, vol.179, pp.263-268, 2016.

V. Neocleous, C. Shammas, M. M. Phelan, S. Nicolaou, L. A. Phylactou et al., In silico analysis of a novel MKRN3 missense mutation in familial central precocious puberty, Clin Endocrinol (Oxf), vol.84, issue.1, pp.80-84, 2016.

J. Nishioka, H. Shima, M. Fukami, S. Yatsuga, T. Matsumoto et al., The first Japanese case of central precocious puberty with a novel MKRN3 mutation, Hum Genome Var, vol.4, p.17017, 2017.

D. Simon, I. Ba, N. Mekhail, E. Ecosse, A. Paulsen et al., Les mutations du gène MKRN3 sont fréquemment retrouvées dans les pubertés précoces centrales idiopathiques (PPC i) familiales, vol.76, pp.315-321, 2015.

D. Simon, I. Ba, N. Mekhail, E. Ecosse, A. Paulsen et al., Mutations in the maternally imprinted gene MKRN3 are common in familial central precocious puberty, Eur J Endocrinol, vol.174, issue.1, pp.1-8, 2016.

J. R. Perry, F. Day, C. E. Elks, P. Sulem, D. J. Thompson et al., Parent-of-originspecific allelic associations among 106 genomic loci for age at menarche, Nature, vol.514, issue.7520, pp.92-99, 2014.

R. Lakshman, N. G. Forouhi, S. J. Sharp, R. Luben, S. A. Bingham et al., Early age at menarche associated with cardiovascular disease and mortality, J Clin Endocrinol Metab, vol.94, issue.12, pp.4953-60, 2009.

R. Lakshman, N. Forouhi, R. Luben, S. Bingham, K. Khaw et al., Association between age at menarche and risk of diabetes in adults: results from the EPIC-Norfolk cohort study, Diabetologia, vol.51, issue.5, pp.781-787, 2008.

C. He, C. Zhang, D. J. Hunter, S. E. Hankinson, B. Louis et al., Age at menarche and risk of type 2 diabetes: results from 2 large prospective cohort studies, Am J Epidemiol, vol.171, issue.3, pp.334-378, 2010.

A. Dauber, M. Cunha-silva, D. B. Macedo, V. N. Brito, A. P. Abreu et al., Paternally Inherited DLK1 Deletion Associated With Familial Central Precocious Puberty, J Clin Endocrinol Metab, vol.102, issue.5, pp.1557-67, 2017.