La transplantation d'utérus : une nouvelle approche en matière d'AMP ? Revue de la littérature

Abstract : Introduction: In 2014, the first live birth post uterus transplantation (UT) had proven that the method was relevant to the human body. Then, many countries have started clinical trials to help women with uterine factor infertility. Objectives: Identify the surgical, medical, obstetrical or gynecological prognosis of the receiving women in case of UT. Identify the early neonatal prognosis of the children born from a UT pregnancy on a woman with uterine factor infertility. Method: Literature review essentially composed of case reports. Results: In total, 18 cases of UT are identified in the scientific literature. The recoil is too weak. The risks of such an intervention are real, for both the living donor and the recipient. The absolute success rate found in this study is only 28%. Almost 2 transplanted uteruses on 5 have been early removed because of medical complications. The births have been premature in more of 80% of the cases, often due to a gestational pathology. Furthermore, for the 6 children identified in the study, the risks are not established yet. They all must be fallowed for a several years, so must their mothers. Conclusion: The poor effectives of the study don't let access at any definitive conclusion about uterus transplantation and the results aren't transposable to the general population. However, and despite many ethical questions raised, it could be possible to see the UT included in the medically assisted procreation in the next few years.
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Sarah Lienart. La transplantation d'utérus : une nouvelle approche en matière d'AMP ? Revue de la littérature. Gynécologie et obstétrique. 2018. ⟨dumas-01957526⟩

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