Effets à long terme de la pollution atmosphérique sur les maladies cardiovasculaires : revue de littérature

Abstract : Cardiovascular diseases (CVD) are the leading cause of chronic morbidity in the world. To our knowledge, no literature review has assessed the associations between long-term exposure to air pollution (AP) and all CVD outcomes. The objective of this review was to summarize current knowledge on the impact of long-term exposure of AP on CVD in adults. All studies published in French or English in refereed journals were searched on Pubmed. Among the studies of our request, 75 studies including 6 meta-analyzes were selected. Most studies showed a positive and statistically significant relationship between long-term exposure to AP and the following outcomes: incidence or recurrence of CVD (combination of multiple CVD), progression of atherosclerosis, and incidence of ischemic heart disease, stroke and hypertension. These associations were stronger among women and among vulnerable people (elderly, diabetics). The most implicated indicators of exposure were fine particles and road traffic indicators. We have not been able to draw conclusions for studies evaluating the long-term effects of AP on some CVD outcomes such as cardiac arrhythmia, heart failure or venous thromboembolic diseases, due to the small number of studies. Adverse effects of long-term exposure to AP on the main CVD outcomes has well-established. However, further studies are needed to clarify some associations.
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Master Thesis
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Anita Balestier-Stengel. Effets à long terme de la pollution atmosphérique sur les maladies cardiovasculaires : revue de littérature. Médecine humaine et pathologie. 2017. ⟨dumas-01958171⟩



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