Estimation de la prévalence de la prescription des antidépresseurs en médecine ambulatoire chez les personnes âgées de plus de 80 ans

Abstract : Introduction: Depression in the elderly is a complex diagnosis. its frequency estimated at 10 to 15%. The objective of the study is to estimate the prevalence of the prescription of antidepressants in outpatients aged 80 and over and to identify the associated social and medical factors. Methods: An observational, analytical, prospective and monocentric study was conducted in the Internal Medicine - Post Emergency Department of the teaching hospital La Timone in Marseilles from March 2016 to March 2017, including hospitalized patients aged 80 or above coming from their usual place of life (patients transferred from another department or hospitalized recently were excluded). Using a questionnaire, socio-demographic and medical data were analysed. Two groups of patients, with and without antidepressant, were compared. Results: 402 patients were included, with a median age of 88 years. Prevalence of antidepressant prescription was 25%, and was associated with a risk of falls (p< 0.03), with the presence of cognitive disorders (p<0,001), and a co-prescription of anxiolytics (p<0.0001) and neuroleptics (p=0,002). In 77% of the cases, a potential drug interaction was found between the antidepressant and at least one of the other drugs on the usual prescription. Conclusion: The prevalence of prescription antidepressants is found in this study to be higher than the frequency of severe depression in this age group, and associated with the presence of cognitive disorders.
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Anaïs Courcier. Estimation de la prévalence de la prescription des antidépresseurs en médecine ambulatoire chez les personnes âgées de plus de 80 ans. Sciences du Vivant [q-bio]. 2018. ⟨dumas-01977059⟩

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