Enjeux politiques, économiques et éthiques de CRISPR/Cas9 en Europe

Abstract : CRISPR/Cas9 is a new genome modification tool that is affordable and easy to use. Its possible applications represent an important political challenge worldwide. This is a major scientific discovery, promising many health innovations. Economically speaking, countries have an interest in investing in CRISPR/Cas9 applied research through the associated promise of gains (patent protection). Despite this, the applications of CRISPR/Cas9 raise many ethical issues, particularly related to its use in humans. Two limits are highlighted: one between the manipulation of somatic cells and the manipulation of germ cells, the other between the treatment and the improvement of humans. From these two barriers flow all the ethical issues associated with CRISPR/Case9. From a European perspective, many different national legislations exist on the subject. In addition, several actions are planned in Europe and worldwide to develop regulations around the modification of the human genome. The main conclusions are that a moratorium should be put in place and that international legislation should be drafted on the subject. Although many difficulties are raised, legislating on the subject seems to be the best solution, bearing in mind that a law is not fixed in time and can evolve after it has been adopted.
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Master Thesis
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Laetitia Agay. Enjeux politiques, économiques et éthiques de CRISPR/Cas9 en Europe. Sciences pharmaceutiques. 2019. ⟨dumas-01981442⟩

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