Apport d'une occlusion temporaire de l'œil amblyope préalable à un entraînement binoculaire pour le traitement de l'amblyopie fixée

Abstract : Objectives: Dichoptic movie viewing significantly improves visual acuity in amblyopia on children. Moreover, short-term occlusion of the amblyopic eye can transiently increase its contribution to binocular fusion after patch removal. In this study, we first asked whether passive dichoptic movie viewing could increase the visual function of subjects beyond the critical period. Secondly we tested if this effect could be enhanced by short-term monocular occlusion of the amblyopic eye. Materials and Methods: 17 subjects presenting fixed and functional amblyopia, aged from 9 to 67 yo, participated in this study. 10 subjects followed 6 sessions of 1.5 hour for 2 weeks of passive dichoptic movie viewing (non-patched group) and 7 subjects, prior to each of these sessions, had to wear an occluding patch of the amblyopic eye for two hours (patched group). Best-corrected visual acuity, monocular contrast sensitivity, interocular balance and stereoacuity were measured at baseline, at the outcome of the training and at a follow-up one month later. Results: For the non-patched group, mean amblyopic eye visual acuity significantly (p<0.05) improved from 0.54 ± 0.37 logMAR to 0.46 ± 0.38 logMAR, equivalent to almost one line improvement. For the patched group, mean amblyopic eye visual acuity significantly improved from 0.62 ± 0.40 to 0.43 ± 0.28 (p<0.05) equivalent to almost two lines improvement. No significant improvement was observed for the other visual functions tested. Conclusions: Our training method improves visual functions of subjects beyond the critical period. The addition of a short-term monocular occlusion to the training shows promising results.
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Lauren Sauvan. Apport d'une occlusion temporaire de l'œil amblyope préalable à un entraînement binoculaire pour le traitement de l'amblyopie fixée. Sciences du Vivant [q-bio]. 2018. ⟨dumas-02028164⟩

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