Angio-œdèmes de l'adulte et de l'enfant : mise au point en 2018

Abstract : Introduction: Angioedema is a common pathology, characterized by swelling of subcutaneous or mucosal tissues, localized and transient. It can be classified by the underlying mechanism: histaminergic, bradykinin and idiopathic (unknown mechanism probably histaminergic and bradykinin-mediated). The main purpose of this review is to synthesize recent data and updates on angioedema. The secondary purpose is to draw up a standardized patient file in order to facilitate patient’s care throughout consultation in our hospital department. Materials and methods: Selected recent scientific articles published from Pubmed, Google Scholar, Cochrane Library and specialized journals. Results: 208 references were compiled. If angioedema is a common symptom from multiple aetiologies, its clinical features and associated signs lead to diagnostic direction on the causal mechanism. The most common are histamine, non-IgE-mediated, benign and often associated with urticaria. Angioedema due to anaphylaxis and angioedema due to bradykinin are rare but the upper airways damage could lead to death by asphyxiation. Clinical suspicion of the last two mechanisms would require additional biological tests for confirmation. Treatment of angioedema is based on acute treatment and the setting up of basic treatment in case of recurrent and disabling crises. Measures associated with this treatment are also essential, therapeutic education being at the forefront. Conclusion: Angioedema is a frequent pathology, only serious in rare cases, which requires an adapted care by trained medical staff.
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https://dumas.ccsd.cnrs.fr/dumas-02049027
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Submitted on : Tuesday, February 26, 2019 - 9:26:58 AM
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Audrey Chambelland. Angio-œdèmes de l'adulte et de l'enfant : mise au point en 2018. Sciences du Vivant [q-bio]. 2018. ⟨dumas-02049027⟩

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