P. Elliott, B. Andersson, and E. Arbustini, Classification of the Cardiomyopathies: a Position Statement from the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases, Eur Heart J, vol.29, issue.2, pp.270-276, 2007.

B. J. Maron, J. M. Gardin, J. M. Flack, S. S. Gidding, T. T. Kurosaki et al., Prevalence of Hypertrophic Cardiomyopathy in a General Population of Young Adults: Echocardiographic Analysis of 4111 Subjects in the CARDIA Study, Circulation, vol.92, issue.4, pp.785-794, 1995.

B. J. Maron, Hypertrophic Cardiomyopathy: A Systematic Review, JAMA, vol.287, issue.10, pp.1308-1328, 2002.

S. E. Hughes, The Pathology of Hypertrophic Cardiomyopathy, Histopathology, vol.44, issue.5, pp.412-439, 2013.

M. S. Maron, I. Olivotto, and S. Betocchi, Effect of Left Ventricular Outflow Tract Obstruction on Clinical Outcome in Hypertrophic Cardiomyopathy, N Engl J Med, vol.348, issue.4, pp.295-303, 2003.

B. J. Gersh, B. J. Maron, and R. O. Bonow, ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, Circulation, vol.124, issue.24, pp.783-831, 2011.

, ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC), Eur Heart J, vol.35, issue.39, pp.2733-79, 2014.

J. M. Gilgenkrantz, F. Cherrier, H. Petitier, B. Dodinot, M. Houplon et al., Obstructive Cardiomyopathy of the Left Ventricle with Complete Auriculo-ventricular Block. Therapeutic Considerations. Arch Mal Coeur Vaiss, vol.61, pp.439-53, 1968.

L. Fananapazir, R. O. Cannon, D. Tripodi, and J. A. Panza, Impact of Dual-chamber Permanent Pacing in Patients with Obstructive Hypertrophic Cardiomyopathy with Symptoms Refractory to Verapamil and Beta-adrenergic Blocker Therapy, Circulation, vol.85, issue.6, pp.2149-61, 1992.

L. Fananapazir, N. D. Epstein, R. V. Curiel, J. A. Panza, D. Tripodi et al., Long-term Results of Dual-chamber (DDD) Pacing in Obstructive Hypertrophic Cardiomyopathy. Evidence for Progressive Symptomatic and Hemodynamic Improvement and Reduction of Left Ventricular Hypertrophy, Circulation, vol.90, issue.6, pp.2731-2773, 1994.

L. Kappenberger, C. Linde, and C. Daubert, Pacing in Hypertrophic Obstructive Cardiomyopathy. A Randomized Crossover Study. PIC Study Group, Eur Heart J, vol.18, issue.8, pp.1249-56, 1997.

R. A. Nishimura, J. M. Trusty, and D. L. Hayes, Dual-chamber Pacing for Hypertrophic Cardiomyopathy: a Randomized, Double-blind, Crossover Trial, J Am Coll Cardiol, vol.29, issue.2, pp.435-476, 1997.

B. J. Maron, R. A. Nishimura, W. J. Mckenna, H. Rakowski, M. E. Josephson et al., Assessment of Permanent Dual-chamber Pacing as a Treatment for Drug-refractory Symptomatic Patients with Obstructive Hypertrophic Cardiomyopathy. A Randomized, Double-blind, Crossover study (M-PATHY), Circulation, vol.99, issue.22, pp.2927-2960, 1999.

M. Qintar, A. Morad, and H. Alhawasli, Pacing for Drug-refractory or Drug-intolerant Hypertrophic Cardiomyopathy, Cochrane Database Syst Rev, issue.5, p.8523, 2012.

E. Galve, A. Sambola, and G. Saldaña, Late Benefits of Dual-chamber Pacing in Obstructive Hypertrophic Cardiomyopathy: a 10-year Follow-up Study, Heart Br Card Soc, vol.96, issue.5, pp.352-358, 2010.

A. Lucon, L. Palud, and D. Pavin, Very Late Effects of Dual Chamber Pacing Therapy for Obstructive Hypertrophic Cardiomyopathy, Arch Cardiovasc Dis, vol.106, issue.6-7, pp.373-81, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00880099

P. H. Pak, W. L. Maughan, K. L. Baughman, and R. S. Kieval, Mechanism of Acute Mechanical Benefit From VDD Pacing in Hypertrophied Heart, Circulation, vol.98, pp.242-248, 1998.

K. Okada, S. Kaga, and T. Mikami, Characteristic Systolic Waveform of Left Ventricular Longitudinal Strain Rate in Patients with Hypertrophic Cardiomyopathy, Heart Vessels, vol.32, issue.5, pp.591-600, 2017.

D. , A. A. Caso, P. Severino, and S. , Prognostic Value of Intra-left Ventricular Electromechanical Asynchrony in Patients with Hypertrophic Cardiomyopathy, Eur Heart J, vol.27, issue.11, pp.1311-1319, 2006.

C. A. Dumont, L. Monserrat, and R. Soler, Left Ventricular Asynchrony in Patients with Hypertrophic Cardiomyopathy: Its Determinants and its Relation to Left Ventricular Function, J Am Soc Echocardiogr, vol.20, issue.11, pp.1247-52, 2007.

D. , A. A. Caso, P. Severino, and S. , Association between Intraventricular Myocardial Systolic Dyssynchrony and Ventricular Arrhythmias in Patients with Hypertrophic Cardiomyopathy, Echocardiography, vol.22, issue.7, pp.571-579, 2005.

J. Duchateau, C. Cornolle, and J. Peyrou, Abnormal Left Ventricular Contraction Sequence in Hypertrophic Cardiomyopathy Patients: First Description of Hypersynchrony and Invert Synchrony, Ultrasound Med Biol, vol.41, issue.6, pp.1632-1641, 2015.

B. Pirat, D. S. Khoury, and C. J. Hartley, A Novel Feature-Tracking Echocardiographic Method for the Quantitation of Regional Myocardial Function, J Am Coll Cardiol, vol.51, issue.6, pp.651-660, 2008.

Y. Rudy, Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates in Humans, Circ Res, vol.112, issue.5, pp.863-74, 2013.

C. Ramanathan, P. Jia, R. Ghanem, K. Ryu, and Y. Rudy, Activation and Repolarization of the Normal Human Heart under Complete Physiological Conditions, Proc Natl Acad Sci, vol.103, issue.16, pp.6309-6323, 2006.

P. P. Sengupta, B. K. Khandheria, and J. Korinek, Apex-to-Base Dispersion in Regional Timing of Left Ventricular Shortening and Lengthening, J Am Coll Cardiol, vol.47, issue.1, pp.163-72, 2006.

C. O'mahony, F. Jichi, and M. Pavlou, A Novel Clinical Risk Prediction Model for Sudden Cardiac Death in Hypertrophic Cardiomyopathy (HCM Risk-SCD), Eur Heart J, vol.35, issue.30, pp.2010-2030, 2014.

J. S. Gottdiener, J. Bednarz, and R. Devereux, American Society of Echocardiography Recommendations for use of Echocardiography in Clinical Trials: A Report from the American Society of Echocardiography's Guidelines and Standards Committee and the Task Force on Echocardiography in Clinical Trials, J Am Soc Echocardiogr, vol.17, issue.10, pp.1086-119, 2004.

R. M. Lang, M. Bierig, and R. B. Devereux, Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology, J Am Soc Echocardiogr, vol.18, issue.12, pp.1440-63, 2005.

B. J. Maron, J. S. Gottdiener, and S. E. Epstein, Patterns and Significance of Distribution of Left Ventricular Hypertrophy in Hypertrophic Cardiomyopathy: A Wide Angle, Two-dimensional Echocardiographic Study of 125 Patients, Am J Cardiol, vol.48, issue.3, pp.418-446, 1981.

R. Sicari, P. Nihoyannopoulos, and A. Evangelista, Stress Echocardiography Expert Consensus Statement of the European Association of Echocardiography (EAE) (a registered branch of the ESC), Eur J Echocardiogr, vol.9, issue.4, pp.415-452, 2008.

M. C. Dulce, G. H. Mostbeck, K. K. Friese, G. R. Caputo, and C. B. Higgins, Quantification of the Left Ventricular Volumes and Function with cine MR imaging: Comparison of Geometric Models with Three-dimensional Data, Radiology, vol.188, issue.2, pp.371-377, 1993.

F. Mongeon, M. Jerosch-herold, O. R. Coelho-filho, R. Blankstein, R. H. Falk et al., Quantification of Extracellular Matrix Expansion by CMR in Infiltrative Heart Disease, JACC Cardiovasc Imaging, vol.5, issue.9, pp.897-907, 2012.

K. Serri, P. Reant, and M. Lafitte, Global and Regional Myocardial Function Quantification by Two-Dimensional Strain: Application in Hypertrophic Cardiomyopathy, J Am Coll Cardiol, vol.47, issue.6, pp.1175-81, 2006.

T. M. Stokke, N. E. Hasselberg, and M. K. Smedsrud, Geometry as a Confounder When Assessing Ventricular Systolic Function, J Am Coll Cardiol, vol.70, issue.8, pp.942-54, 2017.

D. E. Michele and J. M. Metzger, Physiological Consequences of Tropomyosin Mutations Associated with Cardiac and Skeletal Myopathies, J Mol Med, vol.78, issue.10, pp.543-53, 2000.

H. Yamashita, M. J. Tyska, D. M. Warshaw, S. Lowey, and K. M. Trybus, Functional Consequences of Mutations in the Smooth Muscle Myosin Heavy Chain at Sites Implicated in Familial Hypertrophic Cardiomyopathy, J Biol Chem, vol.275, issue.36, pp.28045-52, 2000.

R. Sepp, N. J. Severs, and R. G. Gourdie, Altered Patterns of Cardiac Intercellular Junction Distribution in Hypertrophic Cardiomyopathy, Heart, vol.76, issue.5, pp.412-419, 1996.

B. D. Nam, S. M. Kim, H. N. Jung, Y. Kim, Y. H. Choe et al., Comparison of Quantitative Imaging Parameters using Cardiovascular Magnetic Resonance Between Cardiac Amyloidosis and Hypertrophic Cardiomyopathy: Inversion Time Scout versus T1 Mapping, Int J Cardiovasc Imaging, vol.72, issue.2, pp.199-204, 1993.

F. W. Prinzen, T. Delhaas, T. Arts, and R. S. Reneman, Regional Electromechanical Coupling During Ventricular Pacing, Cardiac Arrhythmias, Pacing & Electrophysiology, pp.353-362, 1998.

R. Eschalier, S. Ploux, and J. Lumens, Detailed Analysis of Ventricular Activation Sequences during Right Ventricular Apical Pacing and Left Bundle Branch Block and the Potential Implications for Cardiac Resynchronization Therapy, Heart Rhythm, vol.12, issue.1, pp.137-180, 2015.

P. P. Sengupta, B. K. Khandheria, J. Korinek, J. Wang, and M. Belohlavek, Biphasic Tissue Doppler Waveforms during Isovolumic Phases are Associated with Asynchronous Deformation of Subendocardial and Subepicardial Layers, J Appl Physiol, vol.99, issue.3, pp.1104-1115, 2005.

, Au moment d'être admis(e) à exercer la médecine, je promets et je jure d'être fidèle aux lois de l'honneur et de la probité

, Mon premier souci sera de rétablir, de préserver ou de promouvoir la santé dans tous ses éléments, physiques et mentaux

, Je respecterai toutes les personnes, leur autonomie et leur volonté, sans aucune discrimination selon leur état ou leurs convictions. J'interviendrai pour les protéger si elles sont affaiblies, vulnérables ou menacées dans leur intégrité ou leur dignité. Même sous la contrainte

, Je ne tromperai jamais leur confiance et n'exploiterai pas le pouvoir hérité des circonstances pour forcer les consciences

, Je donnerai mes soins à l'indigent et à quiconque me les demandera. Je ne me laisserai pas influencer par la soif du gain ou la recherche de la gloire

, Reçu(e) à l'intérieur des maisons, je respecterai les secrets des foyers et ma conduite ne servira pas à corrompre les moeurs

, Je ferai tout pour soulager les souffrances. Je ne prolongerai pas abusivement les agonies. Je ne provoquerai jamais la mort délibérément

, Je n'entreprendrai rien qui dépasse mes compétences. Je les entretiendrai et les perfectionnerai pour assurer au mieux les services qui me seront demandés

, J'apporterai mon aide à mes confrères ainsi qu'à leurs familles dans l'adversité

, Que les hommes et mes confrères m'accordent leur estime si je suis fidèle à mes promesses

, que je sois déshonoré(e) et méprisé(e) si j'y manque