Stress et développement de la polyarthrite rhumatoïde : étude cas-témoins sur le rôle des évènements de vie, l’évaluation du stress et les stratégies de coping

Abstract : Objectives: to assess the stressful life events preceding the onset of symptoms in rheumatoid arthritis (RA), and to assess how RA patients evaluate and cope with stressors, together with the influence of gender and age. Methods: a case-control study was performed, comparing patients recently diagnosed with RA to age and gender-matched control subjects recently hospitalized for an unplanned surgical procedure not known to be influenced by stress. The Social Readjustment Rating Scale (SRRS) assessed the cumulative stress induced by stressful life events in the year preceding the onset of symptoms. Coping strategies, stress and anxiety symptoms were evaluated with Ways of Coping Checklist, Perceived Stress Scale, Multidimensional Health Locus of Control Scale, Social Support Questionnaire and State-Trait Anxiety Inventory. Results: seventy-six subjects were included in each group. The mean SRRS score was twice higher in cases compared to controls, with results more consistent in women than in men. The onset of RA symptoms was attributed to a stressful life event responsible for a psychological stress in 54.8% of cases, most often the death of a relative or friend. Scores of perceived stress and coping based on emotions were higher in RA patients. Females attributed more often the onset of RA symptoms to a stressful life event than males (70.2% versus 26.9%) and had a higher state anxiety score. Conclusion: stressful life events could contribute to the onset of RA symptoms, with marked specificities according to gender. Assessing stress and related adjustment strategies could help physicians to better manage the disease.
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Master Thesis
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Vincent Germain. Stress et développement de la polyarthrite rhumatoïde : étude cas-témoins sur le rôle des évènements de vie, l’évaluation du stress et les stratégies de coping. Médecine humaine et pathologie. 2018. ⟨dumas-02074305⟩

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