Analyse informationnelle des facteurs cliniques évoqués dans la pathogénie de l'hémorragie intra-ventriculaire sévère du prématuré‎ : étude réalisée avec les données du CHU Amiens-Picardie 2014-2017

Abstract : Objective. To identify risk factors for severe intraventricular hemorrhage (SIVH) in preterm infants. Study design, Patients, Methods. Retrospectively collected data on pregnancy complications, perinatal factors and treatment of 216 preterm infants born less than 30 weeks of gestation between October 2014 and March 2017 admitted to the tertiary intensive care unit of the university hospital of Amiens-Picardie. Results. The frequency of SIVH was 27 %. Multivariate logistic regression modelling identified patent ductus arteriosus (OR 3.9 (IC 95 % : 1.6 – 9.1)) and multiple transfusion of fresh frozen plasma or platelet concentrate (OR 3.6 (IC 95 % : 1.6 – 8.0)) as independent risk factors. The incidence of SIVH decreased with increasing gestational age and vascular placenta disease. Catecholamine treatment was not different for preterm infants with SIVH. Conclusions. Hemodynamic management and active strategy for control patent ductus arteriosus may decrease the frequency of SIVH. More study are needed to understand impact of vascular placenta diseases and disorders of hemostasis.
Document type :
Master Thesis
Complete list of metadatas

https://dumas.ccsd.cnrs.fr/dumas-02075666
Contributor : Philippe Barbey <>
Submitted on : Thursday, March 21, 2019 - 3:00:52 PM
Last modification on : Monday, May 6, 2019 - 1:17:15 AM
Long-term archiving on : Saturday, June 22, 2019 - 2:41:12 PM

File

Aïmen Bsila. Thèse d'exercic...
Files produced by the author(s)

Identifiers

  • HAL Id : dumas-02075666, version 1

Collections

Citation

Aïmen Bsila. Analyse informationnelle des facteurs cliniques évoqués dans la pathogénie de l'hémorragie intra-ventriculaire sévère du prématuré‎ : étude réalisée avec les données du CHU Amiens-Picardie 2014-2017. Pédiatrie. 2018. ⟨dumas-02075666⟩

Share

Metrics

Record views

15

Files downloads

13