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Master Thesis

Profil évolutif des hémangiomes congénitaux : suivi à long terme de 57 cas

Abstract : Background: congenital hemangiomas (CHs) are rare benign vascular tumors fully developed at birth. Three subtypes of CHs have been described based on their clinical behaviour: rapidly involuting congenital hemangioma (RICH), non involuting congenital hemangioma (NICH) or partially involuting congenital hemangioma (PICH). The objective was to define the clinical, evolutive and paraclinical characteristics of the three subtypes of CHs. Methods: children with CHs attending department of pediatric dermatology at Bordeaux University Hospital over a 13-year period were retrospectively included. Epidemiological, clinical, evolution data, photographs, and imaging results were reviewed. Histological examination of available samples was performed. Results: 57 cases were included: 22 RICH, 22 NICH, and 13 PICH. There was a male predominance and the most common location was the limbs. RICH, NICH and PICH had overlapping characteristics: a single telangiectatic lesion with peripheral pale halo. NICH were flat, whereas RICH and PICH were bulky at birth. Mean age at complete involution of RICH was 13.6 months. 1/3 of CHs having RICH aspect at birth finally had incomplete involution and became PICH. Heart failure and thrombocytopenia were rare complications. PICH were frequently ulcerated. Pain was common for NICH and PICH. Imaging and histological results were relatively similar between the 3 subtypes of CHs. Conclusions: our case series describe the characteristics and the evolution pattern of the three subtypes of CHs with some overlapping features, reinforcing the hypothesis that RICH, NICH and PICH belong to the same pathological spectrum.
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Master Thesis
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Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Thursday, March 21, 2019 - 4:37:28 PM
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  • HAL Id : dumas-02075879, version 1



Victoire Braun. Profil évolutif des hémangiomes congénitaux : suivi à long terme de 57 cas. Médecine humaine et pathologie. 2018. ⟨dumas-02075879⟩



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