Towards the validation of the lactocrine hypothesis for the dairy cow: the role of INSL3 and relaxin

Abstract : The lactocrine hypothesis in the pig is based on the expression of relaxin in the mother’s milk. Knowing that cattle do not produce relaxin, it remains a possibility that such a lactocrine hypothesis in bovines could exist using INSL3, a structurally very similar peptide of the relaxin family. This project’s aim was to i) validate the use of C2C12 as an effective cell model to study the effects of relaxin family peptides on muscle differentiation, as well as to validate the use of new PCR primers as differentiation markers; ii) create and standardize a protocol to measure INSL3 in cow’s milk using TRFIA.
Document type :
Master Thesis
Complete list of metadatas

Cited literature [20 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-02078537
Contributor : Agrocampus Ouest <>
Submitted on : Monday, March 25, 2019 - 2:14:19 PM
Last modification on : Friday, May 31, 2019 - 1:16:20 AM
Long-term archiving on : Wednesday, June 26, 2019 - 2:40:11 PM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : 2028-06-22

Please log in to resquest access to the document

Identifiers

  • HAL Id : dumas-02078537, version 1

Collections

Citation

Lara Bloch Leruth. Towards the validation of the lactocrine hypothesis for the dairy cow: the role of INSL3 and relaxin. Life Sciences [q-bio]. 2018. ⟨dumas-02078537⟩

Share

Metrics

Record views

17