Gliomes et évaluations de la mémoire de travail pré-, per-, post-opératoires : impacts et corrélats anatomo-fonctionnels

Abstract : Patients with infiltrating glioma who are operated on awake condition generally have impaired working memory before and after resection. This experimental study aims to assess the working memory of four patients operated at the Sainte-Anne Hospital Center. This complex cognitive function impacts their quality of life and their return to work. Thus, a fine evaluation of the three components of the working memory is necessary for a better management of these patients. On the one hand, we objectify these deficits by comparing their performances with those of paired control subjects. On the other hand, we compare the evolution of their performances in the three components of the working memory, pre- and post-operative in a cognitive and ecological dimension. Finally, we create work memory tasks to appreciate their feasibility in the operating room in awake condition. Although this study revealed a variability of cognitive profiles, it made it possible to objectify work memory disorders. The complaints in working memory decreased in the few months following the resection. Finally, verbal working memory tasks can be performed in awake surgery condition.
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https://dumas.ccsd.cnrs.fr/dumas-02081101
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Sarah Azghoud, Marie Traineau. Gliomes et évaluations de la mémoire de travail pré-, per-, post-opératoires : impacts et corrélats anatomo-fonctionnels. Sciences cognitives. 2018. ⟨dumas-02081101⟩

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