Langage élaboré et gliomes diffus chez des patients opérés en condition éveillée : une étude longitudinale

Abstract : Introduction : Recent studies have demonstrated the existence of language disorders in patients with diffuse glioma. Nevertheless, the variables influencing patients’ performances in sophisticated language as well as their recovery after surgery remain hardly studied. Therefore, we studied the impact of these gliomas as well as their effect on elaborated language and its evolution.
Material and methods : To do so, we administered a sophisticated language test (ÉLÉA) before and after surgery (between 9 and 20 months after) to a sample of subjects with diffuse glioma, and operated while awake (27 patients before their operation and 12 of them after) .
Results and discussion : We found language disorders both pre-op (in 30% of the sample population) and post-op (in 8% of the sample population). There is no significant effect of the intrinsic variables (related to the patient and its tumor) and extrinsic (speech therapy care, volume of the resection, radiotherapy treatment) variables on the disturbance and on the evolution of the developed language level, however trends can be identified. Before surgery, the presence of sophisticated language disorders appears to be related to the involvement of the left hemisphere and to cognitive impairment associated with language. Farther from surgical resection, the significant improvement in test scores is associated with complete tumor resection and speech therapy follow-up.
Conclusion : In-depth evaluation of the language as well as a specific speech therapy follow-up of patients with diffuse glioma is therefore necessary.
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Marie-Reine Lemarchand, Marine Salomon. Langage élaboré et gliomes diffus chez des patients opérés en condition éveillée : une étude longitudinale. Sciences cognitives. 2018. ⟨dumas-02084161⟩

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