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Master Thesis

Troubles cognitifs chez les personnes agées VIH-positives et perspectives de remédiation cognitive en orthophonie

Abstract : Theoritical context : Antiretroviral therapies’ improvement enabled a decrease of the mortality of persons living with the the human immunodeficiency virus (PLHIV), hereby increasing their life expectancy. An increase in the number of older PLHIV, whose diagnosis is old or recent, raises the issue of their care. HIV infection is associated with several comorbidities and the virus can involve neurocognitive disorders. Cognitive remediation offered to PLHIV with neurocognitive disorders revolves mainly around information processing speed, memory, executive function. There are currently no French studies on elderly PLHIV's neurocognitive disorders, older than 65 years, with undetectable viral load and medical surveillance.
Goal : To characterize disorders of PLHIV older than 65 years with virological control, to determine the kind of cognitive damage and to propose a remediation in speech therapy supported by linguistic tools.
Methods : The study is about 61 PLHIV, tested in six cognitive fields : information processing speed, attention and working memory, memory, learning, executive function and language. Neurocognitive disorders are determined according memory centers' criteria, defined by a normalized score lower than -1.65 DS for at least two cognitive fields.
Results : PLHIV with neurocognitive disorders have significantly lower scores than PLHIV without any neurocognitive disorder in every cognitive fields which suggests an impact on the overall cognitive efficiency. The most affected fields for PLHIV with neurocognitive disorders, listed in increasing level of severity, are the following : information processing speed, language, memory and learning, executive function. Remediation in speech therapy relates to the training of linguistic competences, such as lexical access and evocation, and to the training of underlying cognitive fields with verbal support.
Conclusion : PLHIV with neurocognitive disorders suffer from an overall damage of the cognitive functions, whose major symptom is a global slowdown. Speech therapy can be part of the rehabilitation of this specific population of patients, whose disorders have an impact on language.
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Submitted on : Friday, March 29, 2019 - 3:34:43 PM
Last modification on : Monday, December 14, 2020 - 9:52:35 AM
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  • HAL Id : dumas-02084353, version 1


Camille Bochet, Sarah Jung. Troubles cognitifs chez les personnes agées VIH-positives et perspectives de remédiation cognitive en orthophonie. Sciences cognitives. 2018. ⟨dumas-02084353⟩



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