, Caractéristiques cliniques confortant ou ne confortant pas le diagnostic d'AMS, p.39

. Correlations and . .. Clinico-pathologiques,

. .. Diagnostics-differentiels,

C. Évolution and . .. De-deces,

. .. Explorations-paracliniques,

, 2.1.1 Exploration par Tomographie par émission monophotonique (TEMP ou SPECT en anglais) des transporteurs de la Dopamine (DAT), Techniques d'exploration du fonctionnement de la synapse neurone dopaminergiquestriatum

, Imagerie du métabolisme cérébral par TEP cérébrale au 18-FDG

.. .. Neuroimagerie,

, 69 10.5.4 Évaluation de la thermorégulation et de la sudation, Exploration des symptômes relevant d'une dysautonomie

. .. Potentiels-nouveaux-biomarqueurs, 72 10.7.1 Biologiques (sang et liquide céphalo-rachidien)

, Left lenticular and putaminal nucleus

, Superior (Brodmann areas 8-9) and middle left frontal gyri (cluster dimensions: 117, x = -28, vol.46

, Anterior cerebellar region: right lobules IV / V (cluster dimensions: 128, x = 38, y= -46, z= -32

, Superior (Brodmann areas 8-9) and middle left frontal gyri (cluster dimensions: 127, x = -28, vol.46

, Right posterior cerebellar region: lobule VIIb (crus 2) (cluster dimensions : 188, x = 20, y= -86, z = -34

, Résultats 1. Caractéristiques générales des patients avec AMS Quatre-vingt-cinq patients diagnostiqués avec une AMS « probable

, 9 %) arrêts respiratoires sur stridor et 1 (2,2 %) embolie pulmonaire ; 5 (10,9 %) l'étaient d'un trouble du rythme ou de la conduction cardiaque ; 1 (2,2 %) l'était d'un sepsis sévère à point de départ urinaire

, Profils cliniques (Figure 1)

, Avec l'analyse LCA, le modèle à deux classes a révélé un profil associant les atteintes extrapyramidale, cérébelleuse, ORL et axiale (profil A : 44 patients, 51,8%) et un profil associant les atteintes cérébelleuse et ORL (profil B : 41 patients, vol.48

, Le modèle à trois classes a révélé un premier profil avec atteintes extrapyramidale, axiale, ORL et cérébelleuse (profil 1 : 46 patients, 54,1%), un second profil avec atteintes cérébelleuse et ORL (profil 2 : 30 patients, 35,3%) et un dernier profil avec atteintes cérébelleuse et cognitive

, Le modèle à quatre classes était non convergent donc non exploitable

, Le modèle à trois classes ayant un niveau de fiabilité statistique élevé

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