Évaluation du niveau d'inflammation bronchique via le NO exhalé chez les sportifs présentant un Bronchospasme Induit à l'Exercice au sein d'une population de chasseurs alpins

Abstract : Exercise-Induced Bronchospasm (EIB) particularly affects athletes, especially when the weather is cold and dry. The prevalence of EIB in alpine hunters is 45%. Military personnel with are considered to be Exercise Induced Asthma (EIA) patients in medico-military texts, classifying them temporarily unfit for mountain activities and external operations. The objective of our study is to evaluate the presence of eosinophilic inflammation in nonasthmatic personnel with EIB via exhaled nitric oxide (NO). Materials and methods: it is an observational study conducted within the 7th Alpine Chasseurs Battalion. The diagnosis of EIB is made if the FEV1 rate is ≥10% after exercise. Exhaled NO should be greater than 50 ppb to consider eosinophilic inflammation. These measurements are taken before and after exercise, in plain and at altitude. Results: 58 soldiers participated. The prevalence of EIB in the plain is 52%, and at altitude 46%. No participants had an NO assay greater than 50 ppb, indicating no eosinophilic inflammation. Conclusion: the physiopathology of EIB does not cause eosinophilic inflammation, which differentiates it from AIE. With more powerful studies, these results could be confirmed and could be used to adapt the aptitude texts.
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Submitted on : Thursday, May 2, 2019 - 12:44:25 PM
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Victoria Picquendar. Évaluation du niveau d'inflammation bronchique via le NO exhalé chez les sportifs présentant un Bronchospasme Induit à l'Exercice au sein d'une population de chasseurs alpins. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02117464⟩

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