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, Diaphragmatic function was assessed by airway occlusion pressure (Ptr,stim) within 24 hours of intubation. A second assessment was obtained once the patient could tolerate at least 2 hours of pressure support ventilation

, Between the 2 measures Ptr,stim increased by 47% in 33 patients (55%), decreased by 37% in 27 patients (45%). in Ptr,stim (88%) compared to patients with a decrease (67%) (p = 0.04). Logistic regression identified sepsis at admission as the only predictor of an increase in Ptr, cmH2O while at the second measure Ptr,stim was 6.9

, p <0.01] but a significant increase in Ptr,stim from onset to recovery

, Keywords: diaphragm dysfunction, sepsis, mechanical ventilation, sepsis induced diaphragm dysfunction