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. Ix)-resume, Introduction : La choriorétinopathie séreuse centrale (CRSC) est la quatrième pathologie rétinienne la plus fréquente. La résolution est souvent spontanée, mais il n'existe pas de consensus pour traiter les formes chroniques. Le but de cette étude était d'évaluer l'éplérénone, un anti-aldostérone, dans le traitement des CRSC chroniques

. Matériel, Tous les patients atteints de CRSC évoluant depuis au moins 4 mois ont été inclus et répartis en 2 groupes selon le traitement reçu : éplérénone ou PDT. Nous avons comparé la meilleure acuité visuelle corrigée (MAVC), la résolution et l'épaisseur maculaire à 1, 3 et 6 mois. Résultats : 36 yeux de 35 patients ont été inclus, avec 18 yeux dans chaque groupe. La MAVC a augmenté significativement à 6, Notre étude était rétrospective, monocentrique au CHU d'Amiens de janvier 2012 et février 2018, p.21

. Logmar,

, La taille du décollement séreux rétinien et l'épaisseur maculaire ont diminué significativement à 6

, Le taux de résolution à 6 mois était similaire dans les 2 groupes ( 66,6% versus 61,6% ; p=0,74 )

, Discussion : L'éplérénone a été aussi efficace anatomiquement et fonctionnellement que la PDT dans notre étude

, Conclusion : L'éplérénone est un traitement efficace, utilisable en première intention dans les CRSC non résolutives

, Mots clés : chorio-rétinopathie séreuse centrale, éplérénone, anti-aldostérone, photothérapie dynamique, choroïde, epithélium pigmentaire rétinien, décollement sereux rétinien X) ANNEXES

, Annexe 1 : tableau de conversion de l'acuité visuelle en LogMAR, echelle de Monoyer et fraction décimale