Étude observationnelle rétrospective de pratiques professionnelles liées à l’usage de deux spécialités de fer injectable utilisées dans un centre hospitalier universitaire

Abstract : Background: The February 2014 hospital stockpiling of injectable iron specialties resulted in a significant increase in our institution's purchases of these specialties. Two injectable iron specialities are referenced: sucrose iron and carboxymaltose iron. The indications, methods of use and cost of acquisition being very different, we carried out a study to know the practices of use of injectable iron within our institution. Method : A synthesis of the literature on martial deficiency and the place of injectable iron was conducted to construct a retrospective observational cross-sectional study. This study was conducted from December 2016 to January 2017 on all patients who received at least one injectable iron prescription in our establishment. Results: 305 patients were included, aged on average 67.7 years (+/- 21.8 years). The average length of stay was 14.8 days (+/-18.7). The biological diagnosis of deficiency was performed according to HAS recommendations in 54.8% of cases (n=167). The mean total iron dose received in patients managed with carboxymaltose iron was significantly higher than that received in the sucrose iron group (p < 0.01 ; α = 0.05). Conclusion : Depending on the temporality set by a hospital stay, the use of carboxymaltose iron seems more appropriate. Improvements in the management of biological diagnosis and follow-up of deficient patients are necessary and will be initiated. A new study will be interesting to conduct to analyze the evolution of remote practices of these changes.
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Master Thesis
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Arnaud Tanty. Étude observationnelle rétrospective de pratiques professionnelles liées à l’usage de deux spécialités de fer injectable utilisées dans un centre hospitalier universitaire. Sciences pharmaceutiques. 2018. ⟨dumas-02167354⟩

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