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Master Thesis

The Croatian version of the HSCL-25 scale : a one-dimensional tool to diagnose anxiety and depression in primary care

Abstract : Background : the Hopkins Symptom Checklist in 25 items (HSCL-25) helps to assess anxiety and depression in Primary Care. Anxiety and depression show considerable overlap in primary care. This self-administrated questionnaire is valid, reliable and ergonomic in the original US version. It was translated it into Croatian. This study aimed to determine its internal validity and dimensions by comparing it to the Schedules for Clinical Assessment in Neuropsychiatry in its Croatian version (C-SCAN). Method : a comparative non inferiority, multi-centered, quantitative cross-validation study of C-HSCL-25 in adult Croatian general practice population was carried out. Two groups were formed: C-HSCL-25 ≥1.75 and C-HSCL-25 <1.75. A validated cut-off score of > 1.75 was considered to indicate a clinically relevant level of symptoms of depression and anxiety. In order to obtain two balanced groups, a different method of randomisation was chosen for each group. The C-SCAN was randomly administered to 1 in 2 patients in the C-HSCL-25 ≥1.75 group, and to 1 in 16 in the C-HSCL-25 <1.75 group. The dimensionality using the Principal Component Analisis (PCA) and the internal validity using Cronbach’s alpha were calculated. Results : the overall prevalence of depression was 24.75%. 804 outpatients completed the C-HSCL-25. The Principal Component Analysis showed that C-HSCL-25 is a one-dimensional tool with a Cronbach Alpha of 0.936. Conclusion : the C-HSCL-25 scale has a high eigenvalue. It’s a one-dimensional tool which combined items according anxiety and depression.
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Master Thesis
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Mélodie Macedo. The Croatian version of the HSCL-25 scale : a one-dimensional tool to diagnose anxiety and depression in primary care. Life Sciences [q-bio]. 2019. ⟨dumas-02178874⟩

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