, recherche d'anticorps anti-plaquette avec l'anticorps monoclonal anti-GpIa/IIa en présence de MP est négatif
, Abréviations : A.FOL : acide folinique ; DXM : dexamethasone ; IRINO : irinotecan ; MAIPA : Monoclonal Antibody-specific Immobilization of
, MP : méthylprednisolone ; OXA : oxaliplatine ; ODS : ondensetron ; 5-FU : 5-Fluorouracile. BIBLIOGRAPHIE 1. Jobin F. L'hémostase. Presses Université Laval, Platelet Antigen assay, 1995.
Drug-induced immune thrombocytopenia, N. Engl. J. Med, vol.357, issue.6, pp.580-587, 2007. ,
Drug-induced immune cytopenias: a unifying pathogenetic concept with special emphasis on the role of drug metabolites, Transfus Med Rev, vol.4, issue.1, pp.69-77, 1990. ,
Mechanisms of drug-induced immunologically mediated cytopenias, Transfus Med Rev, vol.7, issue.4, pp.215-229, 1993. ,
Drug-induced immune cytopenias, Toxicology, vol.209, issue.2, pp.149-153, 2005. ,
Immune thrombocytopenia caused by glycoprotein IIb/IIIa inhibitors, Chest, vol.127, issue.2, pp.53-59, 2005. ,
Abciximab readministration: results of the ReoPro Readministration Registry, Circulation, vol.104, issue.8, pp.870-875, 2001. ,
Delayed thrombocytopenia after treatment with abciximab: a distinct clinical entity associated with the immune response to the drug, J. Thromb. Haemost, vol.2, issue.6, pp.985-992, 2004. ,
Thrombocytopenia after second exposure to abciximab is caused by antibodies that recognize abciximab-coated platelets, Blood, vol.99, issue.6, pp.2054-2059, 2002. ,
Teicoplanin-dependent antibodies: detection and characterization, Br. J. Haematol, vol.129, issue.2, pp.279-281, 2005. ,
Patients with quinine-induced immune thrombocytopenia have both "drug-dependent" and "drug-specific" antibodies, Blood, vol.108, issue.3, pp.922-927, 2006. ,
Can drugs cause autoimmune thrombocytopenic purpura?, Semin. Hematol, vol.37, issue.3, pp.229-238, 2000. ,
Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody, Blood, vol.99, issue.4, pp.1230-1236, 2002. ,
Clinical practice. Heparin-induced thrombocytopenia ,
, J. Med, vol.355, issue.8, pp.809-817, 2006.
Heparin-induced thrombocytopenia, Blood, vol.129, issue.21, pp.2864-2872, 2017. ,
Recurrent acute thrombocytopenia in the hospitalized patient: sepsis, DIC, HIT, or antibiotic-induced thrombocytopenia, Am. J. Hematol, vol.85, issue.1, pp.71-74, 2010. ,
Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population-based cohort of 245 patients, 18. van den Bemt PMLA, Meyboom RHB, Egberts ACG. Drug-induced immune thrombocytopenia. Drug Saf, vol.122, issue.6, pp.1243-1252, 2003. ,
Drug-induced thrombocytopenia: clinical data on 309 cases and the effect of corticosteroid therapy, Eur. J. Clin. Pharmacol, vol.54, issue.9, pp.183-189, 1997. ,
Thrombocytopenia induced by noncytotoxic drugs in Denmark 1968-91, J. Intern. Med, vol.239, issue.6, pp.509-515, 1996. ,
Incidence and cause of aplastic anemia, hemolytic anemia, agranulocytosis and thrombocytopenia, Acta Med Scand, vol.210, issue.6, pp.475-479, 1981. ,
Drug-induced blood disorders, JAMA, vol.252, issue.23, pp.3257-3260, 1984. ,
Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study, Blood, vol.82, issue.9, pp.1749-1757, 1986. ,
Drug-induced thrombocytopenia: a systematic review of published case reports, Ann. Intern. Med, vol.129, issue.11, pp.886-890, 1998. ,
Approach to the diagnosis and management of drug-induced immune thrombocytopenia, Transfus Med Rev, vol.27, issue.3, pp.137-145, 2013. ,
Vancomycin-induced immune thrombocytopenia, N. Engl. J. Med, vol.356, issue.9, pp.904-910, 2007. ,
Drug-induced immune thrombocytopenia: pathogenesis, diagnosis, and management, J. Thromb. Haemost, vol.7, issue.6, pp.911-918, 2009. ,
Drug-induced thrombocytopenia: pathogenesis, evaluation, and management, Hematology Am Soc Hematol Educ Program, pp.153-158, 2009. ,
Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin, Am. J. Hematol, vol.81, issue.3, pp.193-198, 2006. ,
Intravenous immune globulin for the treatment of presumed quinidine-induced thrombocytopenia, DICP, vol.24, issue.7-8, pp.693-695, 1990. ,
A kidney biopsy is clearly mandatory to confirm the indication of plasma exchanges in adult haemolytic uraemic syndrome, Ann Med Interne, vol.145, issue.5, pp.369-372, 1994. ,
Oxaliplatin Immune-Induced Syndrome Occurs With Cumulative Administration and Rechallenge: Single Institution Series and Systematic Review Study, Clin Colorectal Cancer, vol.15, issue.3, pp.213-221, 2016. ,
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale, J. Clin. Oncol, vol.23, issue.22, pp.4866-4875, 2005. ,
Clinical pharmacokinetics of oxaliplatin: a critical review, Cancer Chemother. Pharmacol, vol.6, issue.4, pp.925-927, 2000. ,
Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin: two case reports and a review of the literature, J Hematol Oncol, vol.3, issue.7, pp.1453-1459, 2010. ,
Oxaliplatin-induced acute thrombocytopenia, J Cancer Res Ther, vol.12, issue.2, pp.509-514, 2016. ,
Oxaliplatin-induced haemolytic anaemia, Lancet, vol.354, issue.9185, pp.1179-1180, 1999. ,
Oxaliplatin-induced immune pancytopenia, Transfusion, vol.45, issue.5, pp.704-708, 2005. ,
Oxaliplatin-induced immune hemolytic anemia: a case report and review of the literature, Anticancer Drugs, vol.18, issue.8, pp.973-976, 2007. ,
Positive direct and indirect antiglobulin tests associated with oxaliplatin can be due to drug antibody and/or drug-induced nonimmunologic protein adsorption, Transfusion, vol.49, issue.4, pp.711-718, 2009. ,
Oxaliplatin-Induced Leukocytoclastic Vasculitis under Adjuvant Chemotherapy for Colorectal Cancer: Two Cases of a Rare Adverse Event, Case Rep Oncol, vol.6, issue.3, pp.609-615, 2013. ,
A patient with oxaliplatin immune-induced syndrome (OIIS) who also developed leucovorin and palonosetron-associated thrombocytopenia, Hematology, vol.23, issue.7, pp.429-432, 2018. ,
Methylprednisolone-induced immune thrombocytopenia, Blood, vol.115, issue.26, pp.5431-5432, 2010. ,
Monoclonal antibody--specific immobilization of platelet antigens (MAIPA): a new tool for the identification of plateletreactive antibodies, Blood, vol.70, issue.6, pp.1722-1726, 1987. ,
Fetal and neonatal alloimmune thrombocytopenia: predictive factors of intracranial hemorrhage, Transfusion, vol.56, issue.1, pp.59-66, 2016. ,
The MAIPA assay and its applications in immunohaematology, Transfus Med, vol.2, issue.3, pp.181-188, 1992. ,
Impact of immune thrombocytopenia on the clinical course of chronic lymphocytic leukemia, Blood, vol.111, issue.3, pp.1110-1116, 2008. ,
Dermatomyositis and Immune-Mediated Necrotizing Myopathies: A Window on, Autoimmunity and Cancer. Front Immunol, vol.8, p.992, 2017. ,
Drug-induced immune-mediated thrombocytopenia in the intensive care unit, J Clin Anesth, vol.27, issue.7, pp.602-605, 2015. ,
Piperacillin and vancomycin induced severe thrombocytopenia in a hospitalized patient, Platelets, vol.22, issue.4, pp.294-301, 2011. ,
Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies, Blood, vol.131, issue.13, pp.1486-1489, 2018. ,
, Abréviations : DX : dexamethasone ; LE : leucovorine ou acide folinique ; OX : oxaliplatine
Les tests de MAIPA réalisés chez le premier patient (A) mettent en évidence des anticorps anti-GpII/IIIa dépendant de la dexamethasone et de l'acide folinique ainsi que des anticorps anti-GPIb/IX dépendant de l'oxaliplatine. Les tests de MAIPA réalisés chez le second patient (B) mettent en évidence des anticorps anti-GpIIb ,
, Abréviations : DX : dexamethasone ; LE : leucovorine ou acide folinique ; OX : oxaliplatine
Les tests d'adsorption réalisés chez le premier patient (A) en présence de ,