, apesanteur, missions d'observation
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Dry Immersion as a Ground-Based Model of Microgravity Physiological Effects, Front. Physiol, vol.10, p.284, 2019. ,
Ground-Based Facilities for Simulation of Microgravity: Organism-Specific Recommendations for Their Use, and Recommended Terminology, Astrobiology, vol.13, issue.1, pp.1-17, 2013. ,
A mesoscale study of the degradation of bone structural properties in modeled microgravity conditions, J. Mech. Behav. Biomed. Mater, vol.44, pp.61-70, 2015. ,
Responses to spaceflight of mouse mandibular bone and teeth, Arch. Oral Biol, vol.93, pp.163-176, 2018. ,
Forces associated with launch into space do not impact bone fracture healing, Life Sci. Space Res, vol.16, pp.52-62, 2018. ,
Mimicking the effects of spaceflight on bone: Combined effects of disuse and chronic low-dose rate radiation exposure on bone mass in mice, Life Sci. Space Res, vol.15, pp.62-68, 2017. ,
Microgravity promotes osteoclast activity in medaka fish reared at the international space station, Sci. Rep, vol.5, p.14172, 2015. ,
Effects of spaceflight on the murine mandible: Possible factors mediating skeletal changes in non-weight bearing bones of the head, Bone, vol.83, pp.156-161, 2016. ,
Simulating the Lunar Environment: Partial Weightbearing and High-LET Radiation-Induce Bone Loss and Increase Sclerostin-Positive Osteocytes, Radiat. Res, vol.186, issue.3, pp.254-263, 2016. ,
Dynamic changes of macaque cancellous bone following head-down bed rest, Aviat. Space Environ. Med, vol.85, issue.2, pp.130-134, 2014. ,
An in vivo ovine model of bone tissue alterations in simulated microgravity conditions, J. Biomech. Eng, vol.136, issue.2, p.32, 2014. ,
Structural analysis of rat bone explants kept in vitro in simulated microgravity conditions, J. Mech. Behav. Biomed.Mater, vol.2, issue.2, pp.164-172, 2009. ,
Bone remodeling regulation under unloading conditions: numerical investigations, Comput. Biol. Med, vol.39, issue.1, pp.46-52, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00395617
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Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss, J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res, vol.21, issue.4, pp.605-615, 2006. ,
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Magnetic resonance microscopy of morphological alterations in mouse trabecular bone structure under conditions of simulated microgravity, Magn. Reson. Med, vol.45, issue.6, pp.1122-1125, 2001. ,
Investigation of bone changes in microgravity during long and short duration space flight: comparison of techniques, Eur. J. Clin. Invest, vol.30, issue.12, pp.1044-1054, 2000. ,
The skeletal effects of spaceflight in growing rats: tissue-specific alterations in mRNA levels for TGF-beta, J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res, vol.10, issue.6, pp.843-848, 1995. ,
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Bone turnover in wild type and pleiotrophin-transgenic mice housed for three months in the international space station (ISS), PLoS ONE, vol.7, issue.3, 2012. ,
Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL-mediated osteoclastogenesis, J. Bone Miner. Metab, vol.29, issue.1, pp.111-122, 2011. ,
The effect of reloading on bone volume, osteoblast number, and osteoprogenitor characteristics: Studies in hind limb unloaded rats, Bone, vol.37, issue.3, pp.370-378, 2005. ,
Spaceflight affects bone formation in rhesus monkeys: A histological and cell culture study, J. Appl. Physiol, vol.93, issue.3, pp.1047-1056, 2002. ,
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Finite Element Analysis of Osteocytes Mechanosensitivity Under Simulated Microgravity, Microgravity Sci. Technol, vol.30, issue.4, pp.469-481, 2018. ,
Fractal analysis of shape changes in murine osteoblasts cultured under simulated microgravity, Rendiconti Lincei, vol.25, issue.1, pp.39-47, 2014. ,
Osteoblasts subjected to spaceflight and simulated space shuttle launch conditions, Vitro Cell. Dev. Biol. -Anim, vol.39, issue.10, pp.454-459, 2003. ,
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Identification of mechanosensitive genes in osteoblasts by comparative microarray studies using the rotating wall vessel and the Random Positioning Machine, J. Cell. Biochem, vol.101, issue.3, pp.587-599, 2007. ,
Reduction of anabolic signals and alteration of osteoblast nuclear morphology in microgravity, J. Cell. Biochem, vol.99, issue.2, pp.435-449, 2006. ,
Combined Effects of Simulated Microgravity and Radiation Exposure on Osteoclast Cell Fusion, Int. J. Mol. Sci, vol.18, issue.11, 2017. ,
Microgravity control of autophagy modulates osteoclastogenesis, Bone, vol.61, pp.25-131, 2014. ,
Microgravity during spaceflight directly affects in vitro osteoclastogenesis and bone resorption, FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol, vol.23, issue.8, pp.2549-2554, 2009. ,
Changes in the numbers of osteoclasts in newts under conditions of microgravity, Adv. Space Res. Off. J. Comm. Space Res. COSPAR, vol.21, issue.8-9, pp.1059-1063, 1998. ,
Microgravity modulation of syncytin-A expression enhance osteoclast formation, J. Cell. Biochem, vol.119, issue.7, pp.5696-5703, 2018. ,
Acute transcriptional up-regulation specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity, Sci. Rep, vol.6, 2016. ,
Microarray Profile of Gene Expression During Osteoclast Differentiation in Modelled Microgravity, J. Cell. Biochem, vol.111, issue.5, pp.1179-1187, 2010. ,
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Myeloid Precursors in the Bone Marrow of Mice after a 30-Day Space Mission on a Bion-M1 Biosatellite, Bull. Exp. Biol. Med, vol.162, issue.4, pp.496-500, 2017. ,
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Maturation of bone and dentin matrices in rats flown on the Soviet biosatellite Cosmos 1887, FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol, vol.4, issue.1, pp.29-33, 1990. ,
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The temporal response of bone to unloading, Endocrinology, vol.118, issue.2, pp.733-742, 1986. ,
Trace element composition and histological analysis of rat bones from the space shuttle, Life Sci, vol.60, issue.9, pp.635-642, 1997. ,
Cortical and Trabecular Bone Microstructure Did Not Recover at Weight-Bearing Skeletal Sites and Progressively Deteriorated at Non-Weight-Bearing Sites During the Year Following International Space Station Missions, J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res, vol.32, issue.10, pp.2010-2021, 2017. ,
Trabecular and cortical bone density and architecture in women after 60 days of bed rest using high-resolution pQCT: WISE, J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res, vol.26, issue.10, pp.2399-2410, 2005. ,
WISE-2005: bed-rest induced changes in bone mineral density in women during 60 days simulated microgravity, Bone, vol.49, issue.4, pp.858-866, 2011. ,
Skeletal effects of long-duration head-down bed rest, Aviat. Space Environ. Med, vol.80, pp.23-28, 2009. ,
Bone mineral and lean tissue loss after long duration space flight, J. Musculoskelet. Neuronal Interact, vol.1, issue.2, pp.157-160, 2000. ,
Effects of long-term microgravity exposure on cancellous and cortical weightbearing bones of cosmonauts, Lancet Lond. Engl, vol.355, issue.9215, pp.1607-1611, 2000. ,
Suppression of osteoblastic phenotypes and modulation of pro-and anti-apoptotic features in normal human osteoblastic cells under a vector-averaged gravity condition, J. Med. Dent. Sci, vol.50, issue.2, pp.167-176, 2003. ,
Space flight is associated with rapid decreases of undercarboxylated osteocalcin and increases of markers of bone resorption without changes in their circadian variation: observations in two cosmonauts, Clin. Chem, vol.46, issue.8, pp.1136-1143, 2000. ,
Gene expression related to the differentiation of osteoblastic cells is altered by microgravity, Bone, vol.22, pp.139-143, 1998. ,
Effects of simulated microgravity on human osteoblast-like cells in culture, Acta Med. Okayama, vol.51, issue.3, pp.135-140, 1997. ,
SCD -Stem Cell Differentiation Toward Osteoblast Onboard the International Space Station, Microgravity Sci. Technol, vol.30, issue.5, pp.713-729, 2018. ,
Effect of microgravity and a high magnetic field on hydroxyapatite deposition and implications for bone loss in space, Appl. Surf. Sci, vol.256, issue.24, pp.7535-7539, 2010. ,
Bone formation and resorption biological markers in cosmonauts during and after a 180-day space flight (Euromir 95), Clin. Chem, vol.44, issue.3, pp.578-585, 1998. ,
Microgravity reduces the differentiation of human osteoblastic MG-63 cells, J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res, vol.12, issue.5, pp.786-794, 1997. ,
Bone metabolism and nutritional status during 30-day head-down-tilt bed rest, J. Appl. Physiol. Bethesda Md, vol.113, issue.10, pp.1519-1529, 1985. ,
Effects of artificial gravity during bed rest on bone metabolism in humans, J. Appl. Physiol. Bethesda Md, vol.107, issue.1, pp.47-53, 1985. ,
Bone markers, calcium metabolism, and calcium kinetics during extendedduration space flight on the mir space station, J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res, vol.20, issue.2, pp.208-218, 2005. ,
Impact of modeled microgravity on migration, differentiation, and cell cycle control of primitive human hematopoietic progenitor cells, Exp. Hematol, vol.32, issue.8, pp.773-781, 2004. ,
The effect of simulated microgravity on osteoblasts is independent of the induction of apoptosis, J. Cell. Biochem, vol.102, issue.2, pp.483-495, 2007. ,
Ultrastructural changes in osteocytes in microgravity conditions, Adv. Space Res. Off. J. Comm. Space Res. COSPAR, vol.30, issue.4, pp.765-770, 2002. ,
Effects of orbital spaceflight on human osteoblastic cell physiology and gene expression, Bone, vol.26, issue.4, pp.325-331, 2000. ,
Effects of masticatory muscle function and bite-raising on mandibular morphology in the growing rat, Swed. Dent. J. Suppl, vol.150, pp.1-49, 2001. ,
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Alendronate as an effective countermeasure to disuse induced bone loss, J. Musculoskelet. Neuronal Interact, vol.2, issue.4, pp.335-343, 2002. ,
Bisphosphonates as a supplement to exercise to protect bone during longduration spaceflight, Osteoporos. Int. J. Establ. Result Coop. Eur. Found. Osteoporos. Natl. Osteoporos. Found. USA, vol.24, issue.7, pp.2105-2114, 2013. ,
Extracting a tooth should be the last resort in space. An interview with former NASA dentist Dr Michael H. Hodapp. USA Dental tribune Asia Pacific Edition, pp.6-7, 2013. ,
Wheeler's dental anatomy, physiology, and occlusion, p.53, 2003. ,
Effects of Clinostat-Microgravity on Bone and Calcium Metabolism in Rats ,
, J Gravit Physiology, vol.7, issue.2, pp.123-124, 2000.
Bone Biochemistry in Rat Femoral Diaphysis after Space Flight, J Gravit Physiology, vol.7, issue.3, pp.7-15, 2000. ,
Bone Ultrastructural Changes in Bion 11 Rhesus Monkeys, J Gravit Physiology, vol.7, issue.1, pp.157-161, 2000. ,
Hemopoiesis in Bone Marrow of Monkeys after Spaceflight ,
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Space Flight Modulates Signal Transduction Pathway of Growth Factor Receptors in Rat Osteoblasts, Biol Sci Space, vol.13, issue.3, pp.142-185, 1999. ,
Quantification of Focal Contacts in Osteoblastic Cells--Effects of Intermittent and Continuous Gravitational Stresses, J Gravit Physiology, vol.3, issue.2, pp.78-79, 1996. ,
Mineral Distribution in Rat Skeletons after Exposure to a Microgravity Model, J Gravit Physiology, vol.2, issue.1, pp.115-116, 1995. ,
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Effects of 7-Day Space Flight on Weight-Bearing and Non-Weight-Bearing Bones in Rats (Cosmos 1667), Physiologist, vol.30, issue.1, pp.45-46, 1987. ,
Osteoblast Histogenesis in Periodontal Ligament and Tibial Metaphysis during Simulated Weightlessness. Aviat Space and Environ Med, vol.57, pp.1125-1155, 1986. ,
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Fracture Risk and Spaceflight: Mechanisms Involved in Microgravity-Related Calcium Loss from Bone, Annals of Biomedical Engineering, vol.28, issue.1, 2000. ,
Simulating Certain Aspects of Hypogravity: Effects on Bone Maturation in the Non-Weight Bearing Skeleton, Aviat Space and Environ Med, vol.54, issue.12 I, pp.1080-1084, 1983. ,
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Effects of microgravity on bone healing in a rat fibular osteotomy model, Clin Orthop Relat Res, issue.318, pp.231-273, 1995. ,
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Expression of PDGF-? receptor, EGF receptor, and receptor adaptor protein Shc in rat osteoblasts during spaceflight, Mol Cell Biochem, vol.202, issue.1-2, pp.63-71, 1999. ,