). Crenarchaeota and P. Le-dimère, PriL est associé à une troisième sous-unité régulatrice, PriX, PriS et PriL sont fusionnées

, Ce domaine C-terminal contient un assemblage organisé d'atomes de fer et de soufre, appelé cluster Fer-Soufre, sensible à l'oxydation. Cela rend donc la purification de la primase entière très difficile en présence d'oxygène, ce cluster ayant tendance à s'oxyder et à déstabiliser le domaine C-terminal de PriL qui le contient

, Si le centre Fer-Soufre est intact, ces travaux permettront de décrire pour la première fois la structure d'une primase hétérodimérique d'Euryarchées (Figure 28 B)

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