C. Terzi, N. C. Arslan, and A. E. Canda, Peritoneal carcinomatosis of gastrointestinal tumors: where are we now?, World J Gastroenterol, vol.20, issue.39, pp.14371-80, 2014.

G. M. Chertow, E. Burdick, M. Honour, J. V. Bonventre, and D. W. Bates, Acute Kidney Injury, Mortality, Length of Stay, and Costs in Hospitalized Patients, JASN, vol.16, issue.11, pp.3365-70, 2005.

. Kdigo-kidney-disease, Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group (2012) KDIGO clinical practice guideline for acute kidney injury, Kidney Int, vol.2, pp.1-138

E. Hoste, S. M. Bagshaw, R. Bellomo, C. M. Cely, R. Colman et al., Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study, Intensive Care Med, vol.41, issue.8, pp.1411-1434, 2015.

N. Srisawat, F. E. Sileanu, R. Murugan, R. Bellomod, P. Calzavacca et al., Variation in risk and mortality of acute kidney injury in critically ill patients: a multicenter study, Am J Nephrol, vol.41, issue.1, pp.81-89, 2015.

A. Arjona-sánchez, A. Cadenas-febres, J. Cabrera-bermon, F. C. Muñoz-casares, A. Casado-adam et al., Assessment of RIFLE and AKIN criteria to define acute renal dysfunction for HIPEC procedures for ovarian and non ovarian peritoneal malignances, Eur J Surg Oncol, vol.42, issue.6, pp.869-76, 2016.

M. E. O'connor, C. J. Kirwan, R. M. Pearse, and J. R. Prowle, Incidence and associations of acute kidney injury after major abdominal surgery, Intensive Care Med, vol.42, issue.4, pp.521-551, 2016.

M. E. Grams, Y. Sang, J. Coresh, S. Ballew, K. Matsushita et al., Acute Kidney Injury After Major Surgery: A Retrospective Analysis of Veterans Health Administration Data, Am J Kidney Dis, vol.67, issue.6, pp.872-80, 2016.

J. P. Cata, A. M. Zavala, A. Van-meter, U. U. Williams, J. Soliz et al., Identification of risk factors associated with postoperative acute kidney injury after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: a retrospective study, Int J Hyperthermia, vol.34, issue.5, pp.538-582, 2018.

O. Glehen, D. Osinsky, E. Cotte, F. Kwiatkowski, G. Freyer et al., Intraperitoneal chemohyperthermia using a closed abdominal procedure and cytoreductive surgery for the treatment of peritoneal carcinomatosis: morbidity and mortality analysis of 216 consecutive procedures, Ann Surg Oncol, vol.10, issue.8, pp.863-872, 2003.

J. Ye, Y. Ren, Z. Wei, J. Peng, C. Chen et al., Nephrotoxicity and long-term survival investigations for patients with peritoneal carcinomatosis using hyperthermic intraperitoneal chemotherapy with cisplatin: A retrospective cohort study, Surg Oncol, vol.27, issue.3, pp.456-61, 2018.

E. Sin, C. S. Chia, G. Tan, K. C. Soo, and M. Teo, Acute kidney injury in ovarian cancer patients undergoing cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy, Int J Hyperthermia, vol.33, issue.6, pp.690-695, 2017.

A. S. Levey, J. P. Bosch, J. B. Lewis, T. Greene, N. Rogers et al., A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group, Ann Intern Med, vol.130, issue.6, pp.461-70, 1999.

M. E. Charlson, P. Pompei, K. L. Ales, and C. R. Mackenzie, A new method of classifying prognostic comorbidity in longitudinal studies: development and validation, J Chronic Dis, vol.40, issue.5, pp.373-83, 1987.

, ASA Physical Status Classification System, 2019.

W. R. Mccabe and G. G. Jackson, Gram-Negative Bacteremia: I. Etiology and Ecology, Arch Intern Med, vol.110, issue.6, pp.847-55, 1962.

L. Gall, J. R. Lemeshow, S. Saulnier, and F. , A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study, JAMA, vol.270, issue.24, pp.2957-63, 1993.

P. Jacquet and P. H. Sugarbaker, Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis, Cancer Treat Res, vol.82, pp.359-74, 1996.

M. Singer, C. S. Deutschman, C. W. Seymour, M. Shankar-hari, D. Annane et al., The Third International Consensus Definitions for Sepsis and Septic Shock

, JAMA, vol.315, issue.8, pp.801-811, 2016.

D. Dindo, N. Demartines, and P. Clavien, Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey, Ann Surg, vol.240, issue.2, pp.205-218, 2004.

S. Kusamura, D. Baratti, R. Younan, B. Laterza, G. D. Oliva et al., Impact of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy on Systemic Toxicity, Ann Surg Oncol, vol.14, issue.9, pp.2550-2558, 2007.

P. Colson, F. Ryckwaert, and P. Coriat, Renin Angiotensin System Antagonists and Anesthesia: Anesthesia & Analgesia, vol.89, pp.1143-55, 1999.

O. Goren and I. Matot, Perioperative acute kidney injury, Br J Anaesth, vol.115, issue.2, pp.3-14, 2015.

R. A. Alpert, M. F. Roizen, W. K. Hamilton, R. J. Storey, W. K. Ehrenfeld et al., Intraoperative Urinary Output Does Not Predict Postoperative Renal Function in Patients Undergoing Abdominal Aortic Revascularization: Survey of Anesthesiology, vol.29, p.131, 1985.

R. G. Hahn, Volume kinetics for infusion fluids, Anesthesiology, vol.113, issue.2, pp.470-81, 2010.

S. Quan, N. Pannu, T. Wilson, C. Ball, Z. Tan et al., Prognostic implications of adding urine output to serum creatinine measurements for staging of acute kidney injury after major surgery: a cohort study, Nephrol Dial Transplant, vol.31, issue.12, pp.2049-56, 2016.

J. A. Kellum, F. E. Sileanu, R. Murugan, N. Lucko, A. D. Shaw et al., Classifying AKI by Urine Output versus Serum Creatinine Level, J Am Soc Nephrol, vol.26, issue.9, pp.2231-2239, 2015.

E. Macedo, R. Malhotra, C. Granado, R. Fedullo, P. Mehta et al., Defining urine output criterion for acute kidney injury in critically ill patients, Nephrol Dial Transplant, vol.26, issue.2, pp.509-524, 2011.

E. Macedo, R. Malhotra, J. Bouchard, S. K. Wynn, and R. L. Mehta, Oliguria is an early predictor of higher mortality in critically ill patients, Kidney Int, vol.80, issue.7, pp.760-767, 2011.

F. Coccolini, D. Corbella, P. Finazzi, P. Brambillasca, A. Benigni et al., Time course of cytokines, hemodynamic and metabolic parameters during hyperthermic intraperitoneal chemotherapy, Minerva Anestesiol, vol.82, issue.3, pp.310-319, 2016.

S. B. Anderberg, T. Luther, and R. Frithiof, Physiological aspects of Toll-like receptor 4 activation in sepsis-induced acute kidney injury, Acta Physiol (Oxf), vol.219, issue.3, pp.573-88, 2017.

W. Druml, B. Metnitz, E. Schaden, P. Bauer, and P. Metnitz, Impact of body mass on incidence and prognosis of acute kidney injury requiring renal replacement therapy, Intensive Care Med, vol.36, issue.7, pp.1221-1229, 2010.

J. Gameiro, J. A. Fonseca, M. Neves, J. S. Lopes, and J. A. , Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes. Annals of Intensive Care, vol.8, p.22, 2009.

M. Suneja and A. B. Kumar, Obesity and perioperative acute kidney injury: a focused review, J Crit Care, vol.29, issue.4, pp.694-695, 2014.

M. Schetz, D. Jong, A. Deane, A. M. Druml, W. Hemelaar et al., Obesity in the critically ill: a narrative review, Intensive Care Med, vol.45, issue.6, pp.757-69, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02073760

N. Pabla and Z. Dong, Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies. Kidney International, vol.73, pp.994-1007, 2008.

S. A. Naffouje, K. A. Tulla, R. Chorley, N. Armstrong, and G. I. Salti, Acute kidney injury increases the rate of major morbidities in cytoreductive surgery and HIPEC, Ann Med Surg (Lond), vol.35, pp.163-171, 2018.

K. Van-der-speeten, O. A. Stuart, D. Chang, H. Mahteme, and P. H. Sugarbaker, Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis, Cancer Chemother Pharmacol, vol.68, issue.1, pp.147-56, 2011.

R. L. Dedrick, C. E. Myers, P. M. Bungay, and V. T. Devita, Pharmacokinetic rationale for peritoneal drug administration in the treatment of ovarian cancer, Cancer Treat Rep, vol.62, issue.1, pp.1-11, 1978.

S. Mustafa, A. H. Elgazzar, H. Essam, S. Gopinath, and M. Mathew, Hyperthermia alters kidney function and renal scintigraphy, Am J Nephrol, vol.27, issue.3, pp.315-336, 2007.

M. Vlad, N. Ionescu, A. T. Ispas, I. Giuv?r??teanu, E. Ungureanu et al., Morphological changes during acute experimental short-term hyperthermia, Rom J Morphol Embryol, vol.51, issue.4, pp.739-783, 2010.

E. Badoer, Role of the hypothalamic PVN in the regulation of renal sympathetic nerve activity and blood flow during hyperthermia and in heart failure, Am J Physiol Renal Physiol, vol.298, issue.4, pp.839-846, 2010.

J. Hansson, W. Graf, L. Påhlman, P. Nygren, and H. Mahteme, Postoperative adverse events and long-term survival after cytoreductive surgery and intraperitoneal chemotherapy, European Journal of Surgical Oncology, vol.35, issue.2, pp.202-210, 2009.

E. K. Bartlett, C. Meise, R. E. Roses, D. L. Fraker, R. R. Kelz et al., Morbidity and mortality of cytoreduction with intraperitoneal chemotherapy: outcomes from the ACS NSQIP database, Ann Surg Oncol, vol.21, issue.5, pp.1494-500, 2014.

M. Walsh, P. J. Devereaux, A. X. Garg, A. Kurz, A. Turan et al., Relationship between Intraoperative Mean Arterial Pressure and Clinical Outcomes after Noncardiac SurgeryToward an Empirical Definition of Hypotension, Anesthes, vol.119, issue.3, pp.507-522, 2013.

L. Y. Sun, D. N. Wijeysundera, G. A. Tait, and W. S. Beattie, Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery, Anesthesiology, vol.123, issue.3, pp.515-538, 2015.

J. Esquivel, F. Angulo, R. K. Bland, A. D. Stephens, and P. H. Sugarbaker, Hemodynamic and cardiac function parameters during heated intraoperative intraperitoneal chemotherapy using the open "coliseum technique, Ann Surg Oncol, vol.7, issue.4, pp.296-300, 2000.

C. Mavroudis, L. Alevizos, K. M. Stamou, T. Vogiatzaki, S. Eleftheriadis et al., RESUME Introduction : L'insuffisance Rénale Aiguë (IRA) est une complication postopératoire fréquente associée à une forte morbidité et mortalité. Peu d'études se sont intéressées à la survenue d'IRA en postopératoire d'une chimiothérapie hyperthermique intra-péritonéale (CHIP). Le but de cette étude était d'évaluer l'incidence et les facteurs de risque d, Int Surg, vol.100, issue.6, pp.1033-1042, 2015.

M. Matériels, Cette étude rétrospective effectuée au CHU d'Amiens visait à collecter les données péri-opératoires des patients ayant bénéficié d'une CHIP. L'IRA était définie à l'aide des critères KDIGO. La créatinine sanguine et la diurèse postopératoire étaient recueillies quotidiennement entre J0 et J7

C. Fischer, . Et-mann, and . Whitney, Une analyse de régression logistique binaire a permis d'identifier les facteurs associés à la survenue d'une IRA

, 50 patients ont été inclus. L'incidence de l'IRA était de 44%, 2014.

, Conclusion : L'incidence de l'IRA en postopératoire de CHIP était de 44%. La durée d'hospitalisation des patients atteints d'IRA était allongée, impliquant probablement un surcoût de soins de santé. Le sepsis était un facteur de risque indépendamment associé à la survenue d, p = 0,023. L'IMC < 25 était un facteur protecteur : OR 0,257 95% IC (0,069-0,957), p = 0,043, vol.661, pp.269-294

, Mots clés : Atteinte rénale aigüe ; Chimiohyperthermie intrapéritonéale

. Incidence, Chirurgie générale ; Oncologie RESUME Introduction : L'insuffisance Rénale Aiguë (IRA) est une complication postopératoire