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Master Thesis

Influence de l'environnement socio-économique sur le risque de ré-hospitalisation pour causes infectieuses durant la première année de vie d'une cohorte d'enfants nés prématurés et suivis dans le réseau Naître et Devenir-Méditerranée

Abstract : Background: Little is known about how social inequalities affect the health of children born preterm. We aimed to evaluate the impact of socioeconomic factors on the risk of infection-related hospitalization in a cohort of preterm infants followed up in a French medical network. Methods: We included all living children born before 33 weeks of gestation, between September 2006 and August 2014. Participants were followed up in our West-PACA regional medical network up to age 1 y. Data on neonatal morbidity and hospitalizations were collected. Socioeconomic context was estimated with a neighborhood-based socioeconomic deprivation index. We analyzed the association between risk factors and hospital admission with logistic regression analyses. Results: During the one-year follow-up period, 2540 infants were included. Of these, 390 (15.3%) infants were hospitalized for infection, primarily respiratory tract infections (59.3%). After adjusting for various factors, including gestational age, sex, siblings, season of birth, and bronchopulmonary dysplasia, we found that residing in the most deprived neighborhoods was associated with hospital admission for infection (odds ratio: 1.92; 95% confidence interval: 1.31-2.82; p<.001); a socioeconomic deprivation index of 1 (least deprived) was used as the reference. Immaturity (p<.01) and siblings (p<.01) were associated with hospitalization, and female sex was a protective factor (p<0.001). Conclusions: Infants living in the most deprived neighborhoods were at high risk of hospitalization for infection. These results suggested that routine infant follow-up care should take into account the socioeconomic environment. The mechanisms that might give rise to this increased risk are complex and require further investigation.
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https://dumas.ccsd.cnrs.fr/dumas-02367885
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Submitted on : Monday, November 18, 2019 - 11:22:00 AM
Last modification on : Friday, October 23, 2020 - 4:58:53 PM

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Mahé Berland. Influence de l'environnement socio-économique sur le risque de ré-hospitalisation pour causes infectieuses durant la première année de vie d'une cohorte d'enfants nés prématurés et suivis dans le réseau Naître et Devenir-Méditerranée. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02367885⟩

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