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Master Thesis

Le Levothyrox®, une crise du médicament ou une crise de communication ? Analyse des événements, moyens de communication et questionnements sur les problèmes sous-jacents

Abstract : In April 2017, the new formulation of Levothyrox® is put on the market in France. The message sent by the laboratory and the ANSM is clear: it is an improvement but nothing changes for the patients. A month later, the first patients complain of adverse effects, they will total about 30 000. The transmission of information to health professionals was insufficient which allowed to define a real communication problem. The analysis that we carried out highlighted points that may raise questions: the regulatory framework was not adapted, the study of bioequivalence was insufficient and the precedents abroad seem not to have been taken into account. The ANSM reports have concluded that there are no serious problems but also contain data showing a real impact, which some might consider important, on some of the patients. In essence, crises also have origins that come from an underlying ground. Thus, in the manner of the Reason model, the accumulation of risks, details, uncertainties and oversights seems to have led to a situation that we could define as a crisis of the drug as described in our introduction, namely the "occurrence of phenomena affecting the health of populations and often involving a degree of uncertainty".
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02417995
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Submitted on : Wednesday, December 18, 2019 - 2:44:04 PM
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David Bigat. Le Levothyrox®, une crise du médicament ou une crise de communication ? Analyse des événements, moyens de communication et questionnements sur les problèmes sous-jacents. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02417995⟩

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