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, Annexes
, Annexe 1 -Présentation de la structure d'accueil
, Annexe 2 -Taux d'incidence et de mortalité du cancer du sein dans le monde
, Annexe 3 -Principaux facteurs de risque du cancer du sein, p.61
, Annexe 4 -Classification
, Annexe
, Annexe 8 -Graph orienté acyclique
, Annexe 9 -Caractéristiques des sujets en fonction des quintiles d'exposition aux PCB, p.74
, Annexe 10 -Evolution des concentrations en PCB 153 au cours du temps
, Dans la cohorte E3N, les femmes consommant plus de deux verres d'alcool par jour ont risque plus élevé d'avoir un cancer du sein que les femmes ne consommant pas d'alcool
, Cette association n'est retrouvée que pour les cancers post-ménopausiques (HR = 1, p.24
, IC95% : 1,07 -1,44), elle n'est pas significative pour les cancers pré-ménopausiques
, Tabac Si le tabac est reconnu comme cancérogène certain pour l'homme (groupe 1) par le
, CIRC, les résultats des études s'intéressant au lien entre le tabagisme et le cancer du sein sont contradictoires (16). La méta-analyse de 2002 n'a pas mis en évidence d'association statistiquement significative entre le tabagisme et le risque de cancer du sein
, Néanmoins, des études plus récentes ont montré des associations positives, vol.134
, Activité physique Une méta-analyse de 2013 a montré une association inverse entre l'activité physique et le risque de cancer du sein avec un RR combiné de 0, vol.88
, Cette méta-analyse conclue que l'activité physique pourrait réduire considérablement le risque de cancer du sein, IC95% : 0,97-0,99)
, une diminution linéaire statistiquement significative du risque de cinq heures par semaines des activités rigoureuses avaient un RR de 0,62 (IC95% : 0,49-0,78) par rapport à celles n'en pratiquant pas
, IMC) et le risque de cancer du sein diffère selon le statut ménopausique. Pour une augmentation de 5kg/m 2 , une méta-analyse de 2008 a montré des tendances opposées avec un RR de 0,89 (IC95% : 0,84-0,94) chez les femmes pré-ménopausiques et un RR de, vol.1, p.9