, que la toxicologie d'urgence, la prescription des D-Dimères, du BNP/Nt-proBNP et la prise en charge de la douleur thoracique au SAU

A. S. Shah, A. Anand, Y. Sandoval, K. K. Lee, S. W. Smith et al., High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: A cohort study, The Lancet, vol.386, p.8, 2015.

M. Roffi, C. Patrono, J. Collet, C. Mueller, M. Valgimigli et al., 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation, European Heart Journal, vol.37, issue.3, p.48, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01478204

E. Puymirat, T. Simon, C. G. Cottin, Y. Elbaz, M. Coste et al.,

, Acute myocardial infarction: Changes in patient characteristics, management, and 6-month outcomes over a period of 20 years in the FAST-MI program (French registry of acute ST-elevation or non-ST-elevation myocardial infarction, Circulation, vol.136, issue.20, p.11, 1995.

C. Chenevier-gobeaux, L. Deweerdt, A. V. Cantero, R. B. , and D. ,

B. , C. S. Lefèvre, and G. , Multi-centre evaluation of recent troponin assays for the diagnosis of NSTEMI, Practical Laboratory Medicine, vol.11, issue.2, p.9, 2018.

V. Sandfort and D. A. Bluemke, CT calcium scoring. History, current status and outlook. Diagnostic and Interventional Imaging, vol.98, p.7, 2017.

G. Beaune, B. Chanzy, J. Jund, A. L. Razimbaut, and C. Dremont, Impact de la robotisation sur le traitement des analyses de biochimie d'urgence : l'expérience du centre hospitalier de la région d, Annecy. Spectra Biologie, vol.194, issue.5, p.5, 2012.

Z. Mokrani, C. Blanc, N. Illi, F. Peyras, and K. Morin, Épidémiologie des douleurs thoraciques hospitalisees en UHCD, Journal Européen Des Urgences, vol.22, issue.6, p.57, 2009.

M. Roffi, C. Patrono, J. Collet, C. Mueller, M. Valgimigli et al., 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation, European Heart Journal, vol.37, issue.3, p.48, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01478204

E. Puymirat, Evolution de la prise en charge et du pronostic des syndromes coronariens aigus en France entre 1995 et 2010, p.99, 2013.
URL : https://hal.archives-ouvertes.fr/tel-00926886

R. Lozano, M. Naghavi, K. Foreman, S. Lim, K. Shibuya et al., Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study, Lancet, vol.380, issue.9859, p.33, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00827612

, Maladies cardio-neuro-vasculaires / Maladies chroniques et traumatismes / Dossiers thématiques, / Accueil -InVS, 2018.

K. Thygesen, J. Alpert, A. Jaffe, B. Chaitman, J. Bax et al., Fourth universal definition of myocardial infarction, European Heart Journal, vol.40, issue.3, p.33, 2018.

G. Laugaudin, N. Kuster, A. Petiton, F. Leclercq, R. Gervasoni et al., Kinetics of high-sensitivity cardiac troponin T and I differ in patients with ST-segment elevation myocardial infarction treated by primary coronary intervention, European Heart Journal: Acute Cardiovascular Care, vol.5, issue.4, p.9, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01800135

T. Reichlin, R. Twerenbold, C. Maushart, M. Reiter, B. Moehring et al., Risk stratification in patients with unstable angina using absolute serial changes of 3 high-sensitive troponin assays, American Heart Journal, vol.165, issue.3, p.7, 2013.

C. Mueller, Biomarkers and acute coronary syndromes: An update, European Heart Journal, vol.35, issue.9, p.4, 2014.

C. Hamm, J. Bassand, S. Agewall, J. Bax, E. Boersma et al.,

, ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation : The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC), European Heart Journal, vol.32, issue.23, p.55

P. Libby, Current concepts of the pathogenesis of the acute coronary syndromes, Circulation, vol.104, issue.3, p.7, 2001.

D. D. Mcmanus, J. Gore, J. Yarzebski, F. Spencer, D. Lessard et al., Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI, American Journal of Medecine, vol.124, p.7, 2011.

B. Ibanez, S. James, S. Agewall, M. J. Antunes, C. Bucciarelli-ducci et al., ESC Scientific Document Group, ESC 2017 Guidelines for the management of acute myocardial infarction in patients presenting with STsegment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC), European Heart Journal, vol.39, issue.2, p.58, 2018.

L. Campeau, Letter: grading of angina pectoris, Circulation, vol.54, issue.2, 1976.

G. Gosselin, Thérapeutique médicamenteuse agressive de l'angor stable : avec ou sans angioplastie (étude COURAGE), Revue Médicale Suisse, vol.4, p.5, 2008.

J. L. Canto and G. John, Atypical presentations among medicare beneficiaries with unstable angina pectoris, American Journal of Cardiology, vol.90, issue.3, p.5, 2002.

P. Hofliger and V. Piano, Le risque cardiovasculaire global, 2007.

J. O. Robertson, R. Ebrahimi, A. J. Lansky, R. Mehran, G. W. Stone et al., Impact of cigarette smoking on extent of coronary artery disease and prognosis of patients with non-ST-segment elevation acute coronary syndromes: An analysis from the ACUITY trial (acute catheterization and urgent intervention triage strategy), Journal of the American College of Cardiology : Cardiovascular Interventions, vol.7, issue.4, p.7, 2014.

S. Savonitto, D. Ardissino, and E. J. Topol, Prognostic value of the admission electrocardiogram in acute coronary syndromes, Journal of the American Medical Association, vol.281, issue.8, p.6, 1999.

K. G. Aragam, U. U. Tamhane, E. Kline-rogers, J. Li, K. A. Fox et al., Does simplicity compromise accuracy in ACS risk prediction ? A retrospective analysis of the TIMI and GRACE risk scores, PLoS One, vol.4, issue.11, p.9, 2009.

G. Ramsay, M. Podogrodzka, C. Mcclure, and K. A. Fox, Risk prediction in patients presenting with suspected cardiac pain: the GRACE and TIMI risk scores versus clinical evaluation, QJM, vol.100, issue.1, p.7, 2007.

L. C. Correia, F. Ferreira, K. F. Silva, A. Pereira, L. Carvalhal et al., Comparison of ACUITY and CRUSADE Scores in Predicting Major Bleeding during Acute Coronary Syndrome, Arquivos Brasileiros de Cardiologia, vol.105, issue.1, p.7, 2015.

A. Bellemain-appaix, J. Collet, and G. Montalescot, Syndromes coronaires aigus, vol.5, p.21, 2010.

Y. Allali, G. Montalescot, and J. Collet, Quelle dose d'aspirine dans le syndrome coronaire aigu ?, Medecine Therapeutique, vol.14, issue.5, p.10, 2007.

E. Wiel, N. Assez, and P. Goldstein, Stratégie de prise en charge des syndromes coronariens aigus, EMConsulte -Médecine Urgence, vol.7, issue.4, p.15, 2012.

A. Lavoinne and B. Cauliez, Les troponines I et T cardiaques : des marqueurs spécifiques du cardiomyocyte Cardiac troponin I and T : specific biomarkers of cardiomyocyte. La revue de médecine interne, p.9, 2004.

B. Aussillous, L'augmentation de la troponine à la phase aigüe d'un accident vasculaire cérébral : une revue de la littérature, p.83, 2014.

L. T. Disponible,

, Les marqueurs cardiaques dans la maladie coronarienne et l'insuffisance cardiaque en médecine ambulatoire

C. Berroëta, S. Provenchère, A. Mongredien, S. Lasocki, J. Benessiano et al., Dosage des isoformes cardiaques des troponines T ou I : intérêt en cardiologie et en anesthésie-réanimation, Annales françaises d'anesthésie et de réanimation, vol.25, p.11, 2006.

G. Lefevre, Algorithmes d'utilisation des dosages de troponines ultrasensibles, 2017.

F. Apple and A. Jaffe, European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: How to use existing assays clinically and for clinical trials, American Heart Journal, vol.144, issue.6, p.6, 2002.

A. Jaffe, J. Ravkilde, R. Roberts, U. Naslund, F. Apple et al., It's Time for a Change to a Troponin Standard, Circulation, vol.102, issue.11, p.5, 2000.

C. Chenevier-gobeaux, E. Bonnefoy-cudraz, S. Charpentier, M. Dehoux, G. Lefevre et al., Troponine dosée avec un test de haute sensibilité : éléments de réponse aux questions fréquemment posées, Annales françaises de médecine d'urgence, vol.4, p.21, 2014.

, Interprétation des troponines en réanimation. Association Tunisienne de Réanimation, Borsali Falfoul N, 2011.

. Disponible,

B. Cummins, M. Auckland, and P. Cummins, Cardiac-specific troponinl radioimmunoassay in the diagnosis of acute myocardial infarction, American Heart Journal, vol.113, issue.6, p.11, 1987.

F. Apple and P. Collinson, Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays, Clinical Chemistry, vol.58, issue.1, p.8, 2011.

W. Hochholzer, Novel biomarkers in cardiovascular disease: Update, American Heart Journal, vol.160, issue.4, p.12, 2010.

M. Krintus, M. Kozinski, P. Boudry, N. E. Capell, U. Köller et al., European multicenter analytical evaluation of the Abbott ARCHITECT STAT high sensitive troponin I immunoassay, Clinical Chemistry and Laboratory Medicine, vol.52, issue.11, p.8, 2014.

S. A. Love, Y. Sandoval, S. W. Smith, J. Nicholson, J. Cao et al., Incidence of undetectable, measurable, and increased cardiac troponin I concentrations above the 99th percentile using a high-sensitivity vs a contemporary assay in patients presenting to the emergency department, Clinical Chemistry, vol.62, issue.8, p.5, 2016.

A. S. Shah, M. Griffiths, K. K. Lee, D. A. Mcallister, A. L. Hunter et al., High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study, BMJ, vol.350, issue.8, 2015.

F. Apple, Y. Sandoval, A. Jaffe, and J. Ordonez-llanos, Cardiac Troponin Assays: Guide to Understanding Analytical Characteristics and Their Impact on Clinical Care, Clinical Chemistry, vol.63, issue.1, p.8, 2017.

E. Bonnefoy, G. Lefèvre, P. Ray, G. Beaune, and D. Collin-chavagnac, , 2014.

, La Troponine de haute sensibilité au coeur du dialogue Cliniciens Biologistes : Biodébat n°42. Spectra Biologie, vol.208, p.12

H. Shin, B. Jang, T. H. Lim, J. Lee, W. Kim et al., Diagnostic accuracy of adding copeptin to cardiac troponin for non-ST-elevation myocardial infarction: A systematic review and meta-analysis, PLoS One, vol.13, issue.7, p.14, 2018.

M. W. Sherwood, K. Newby, and L. , High-Sensitivity Troponin Assays: Evidence, Indications, and Reasonable Use, Journal of the American Heart Association, vol.3, issue.1, p.10, 2014.

T. Keller, T. Zeller, F. Ojeda, S. Tzikas, L. Lillpopp et al., Serial Changes in Highly Sensitive Troponin I Assay and Early Diagnosis of Myocardial Infarction, Journal of the American Medical Association, vol.306, issue.24, p.10, 2011.

T. Reichlin, A. Irfan, R. Twerenbold, M. Reiter, W. Hochholzer et al., Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction, Circulation, vol.124, issue.2, p.9, 2011.

L. Cullen, C. Mueller, W. A. Parsonage, K. Wildi, J. H. Greenslade et al., Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome, Journal of the American College of Cardiology, vol.62, issue.14, p.7, 2013.

S. Druey, K. Wildi, R. Twerenbold, C. Jaeger, T. Reichlin et al., Early rule-out and rule-in of myocardial infarction using sensitive cardiac Troponin I, International Journal of Cardiology, vol.195, p.7, 2015.

S. Charpentier and C. Chenevier-gobeaux, Recommandations ESC 2015 : exclure ou confirmer le diagnostic d'infarctus du myocarde en 1 heure avec la troponine T hypersensible, Presse Medicale, vol.45, issue.10, p.5, 2016.

A. Mokhtari, C. Borna, P. Gilje, P. Tydén, B. Lindahl et al., A 1-h Combination Algorithm Allows Fast Rule-Out and Rule-In of Major Adverse Cardiac Events, Journal of the American College of Cardiology, vol.67, issue.13, p.9, 2016.

C. Chenevier-gobeaux, G. Lefevre, E. Bonnefoy-cudraz, S. Charpentier, M. Dehoux et al., Why a new algorithm using high-sensitivity cardiac troponins for the rapid rule-out of NSTEMI is not adapted to routine practice, Clinical Chemistry and Laboratory Medecine, vol.54, issue.10, p.2, 2016.

A. P. , Intérêt du dosage de la troponine en dehors des SCA, Cardiologie Pratique, vol.4, p.6, 2015.

W. Masri, E. Hamdi, and P. Descartes, Élévation de la troponine dans des situations cliniques autres que le syndrome coronarien aigu, Annales de Biologie Clinique, vol.75, issue.4, p.8, 2017.

S. Pruvot, G. Galidie, J. F. Bergmann, and I. Mahé, Troponin and others markers of myocardial ischemia injury, which relevance in internal medicine? Revue de, Medecine Interne, vol.27, issue.3, p.11, 2006.

G. Lefevre and C. Morin, Utilisation des marqueurs cardiaques et de la troponine en France, Spectra Biologie, vol.145, issue.5, p.6, 2005.