. E. Derrick and . Fever, a new fever entity : clinical features, diagnosis and laboratory investigation, Rev Infect Dis, vol.5, pp.790-800, 1983.

F. M. Burnet and M. Freeman, Experimental studies on the virus of " Q, Fever. Rev Infect Dis, vol.5, pp.800-808, 1983.

C. Eldin, C. Melenotte, and O. Mediannikov, From Q Fever to Coxiella burnetii infection: a paradigm change, Clin Microbiol Rev, vol.30, pp.115-190, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01496178

D. Raoult, T. Marrie, and J. Mege, Natural history and pathophysiology of Q fever, Lancet Infect Dis, vol.5, pp.219-245, 2005.

M. Million, H. Lepidi, and D. Raoult, Fièvre Q : actualités diagnostiques et thérapeutiques. Médecine et maladies infectieuses, vol.39, pp.82-94, 2009.

R. J. Harris, P. A. Storm, A. Llyod, M. Arens, and B. P. Marmion, Long term persistence of Coxiella burnetii in the host after primary Q fever, Epidemiol Infect, vol.124, pp.543-549, 2000.

B. P. Marmion, P. A. Storm, and J. G. Ayres, Long-term persistence of Coxiella burnetii after acute primary Q fever, QJM, vol.98, pp.7-20, 2005.

O. Glazunova, V. Roux, and O. Freylikman, Coxiella burnetii genotyping. Emerg Infect Dis, vol.11, pp.1211-1218, 2005.

M. G. Madariaga, K. Rezai, G. M. Trenholme, and R. A. Weinstein, Q fever : a biological weapon in your backyard, Lancet Infect Dis, vol.3, pp.709-730, 2003.

J. Delaloye and G. G. , Fièvre Q : une zoonose souvent méconnue. Revue médicale suisse, vol.9, pp.879-84, 2013.

N. J. Clark and R. J. Soares-magalhaes, Airbone geographical dispersal of Q fever from livestock holdings to human communities : a systematic review and critical appraisal of evidence, BMC Infect Dis, vol.18, p.218, 2018.

C. Popescu, A. Lobodan, and R. Dulama, Q fever in urban area -an emerging zoonosis, BMC Infectious Diseases, vol.14, p.86, 2014.

F. Hilbink, M. Penrose, E. Kovacova, and J. Kazar, Q fever is absent from New Zealand, Int J Epidemiol, vol.22, pp.945-994, 1993.

D. Musso, J. Broult, P. Parola, D. Raoult, and P. E. Fournier, Absence of antibodies to Rickettsia spp., Bartonella spp, Ehlichia spp. And Coxiella burnetii in, vol.14, p.255, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-00991782

S. R. Porter, G. Czaplicki, J. Mainil, R. Guattéo, and C. Saegerman, Q fever : current state of knowledge and perspectives of research of a neglected zoonosis, Int J Microbiol, 2011.

F. Dijkstra, W. Van-der-hoek, and N. Wijers, The 2007-2010 Q fever epidemic in the Netherlands : characteristics of notified acute Q fever patients and the association with dairy goat farming, FEMS Immunol Med Microbiol, vol.64, pp.3-12, 2012.

C. C. Wielders, A. M. Wuister, and V. L. De-visser, Characteristics of Hospitalized Acute Q Fever Patients during a Large Epidemic, The Netherlands, PLoS One, vol.9, issue.3, p.91764, 2014.

E. Fanoy, F. Dijkstra, W. Van-der-hoek, P. Schneeberger, J. Van-de-kassteele et al., Familarity of general practitioners with Q fever decreases hospitalisation risk, Neth J Med, vol.76, pp.184-189, 2018.

L. Epelboin, M. Nacher, and A. Mahamat, Q fever in French Guiana : tip of the iceberg or epidemiological exception ?, PloS Negl Trop Dis, vol.10, p.4598, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01847478

L. Epelboin, C. Chesnais, and C. Boullé, Q Fever Pneumonia in French Guiana : prevalence, risk factors and prognostic score, Clin Infect Dis, vol.55, pp.67-74, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01845479

E. Ponlot, L. Oliver, L. Dommergues, L. Bellec, and M. Vernier, Q fever endocarditis : first reported case in Mayotte, Med Mal Infect, vol.48, pp.76-78, 2018.

P. Brouqui, J. M. Rolain, C. Foucault, and D. Raoult, Short report : Q fever and Plasmodium falciparum malaria co-infection in a patient returning from the Comoros archipelago, Am J Trop Med Hyg, vol.73, pp.1028-1030, 2005.

I. Boone, K. Henning, and H. A. , Are brucellosis, Q fever and melioidosis potential causes of febrile illness in Madagascar ?, Acta Trop, vol.172, pp.255-262, 2017.

M. Leone, A. Honstettre, and H. Lepidi, Effect of sex on Coxiella burnetii infection: protective role of 17B-Estradiol, J Infect Dis, vol.189, pp.339-345, 2004.

M. Million and D. Raoult, Recent advances in the study of Q fever epidemiology, diagnosis and management, J Infect, vol.71, pp.2-9, 2015.

D. Raoult, H. Tissot-dupont, and C. Foucault, Q fever 1985-1998 : clinical and epidemiologic features of 1,383 infections, Medecine (Baltimore), vol.79, issue.2, pp.109-132, 2000.

C. Melenotte, C. Protopopescu, and . Million, Clinical features and complications of Coxiella burnetii infections from the French National Reference Center for Q Fever, JAMA Netw Open, vol.1, issue.4, p.181580, 2018.
URL : https://hal.archives-ouvertes.fr/hal-01970209

S. P. Keijmel, C. E. Delsing, and T. Sprong, The Qure study: Q fever fatigue syndromeresponse to treatment; a randomized placebo-controlled trial, BMC Infect Dis, vol.13, p.157, 2013.

G. Morroy, S. P. Keijmel, and C. E. Delsing, Fatigue following acute Q fever : a systematic literature review, PloS One, vol.11, issue.5, p.155884, 2016.

J. Ordi-ros, A. Selva-o'callaghan, F. Monegal-ferran, Y. Monasterio-aspiri, C. Juste-sanchez et al., significance and specificity of antibodies to phospholipids in Q fever, Clin Infect Dis, vol.18, pp.213-221, 1994.

M. Million, N. Bardin, and S. Bessis, Thrombosis and antiphospholipid antibody syndrome during acute Q fever : a cross-sectional study, Medicine, vol.96, p.7578, 2017.

, Protocoles thérapeutiques. Le traitement de la fièvre Q

Y. Mboussou, J. Jaubert, and S. Larrieu, Pregnancy outcomes of Q fever : prospective follow-up study on Reunion island, BMC Infect Dis
URL : https://hal.archives-ouvertes.fr/inserm-02437134

K. A. Bond, L. J. Franklin, B. Sutton, and S. M. Firestone, Q-Vax Q fever vaccine failures, vol.35, pp.7084-7087, 1994.

. Insee and . Institut, National de la statistique et des études économiques. Statistiques et études. Comparateur de territoire-département de La Réunion 974

E. Cardinale, O. Esnault, M. Beral, F. Naze, and A. Michault, Emergence of Coxiella burnetii in ruminants on Reunion Island? Prevalence and Risk factors, PLoS Negl Trop Dis, vol.8, issue.8, p.3055, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01274550

M. Artagnan, La fièvre Q à La Réunion : une pathologie émergente ? Université de Bordeaux 2, UFR des sciences médicales, 2009.

M. B. Gottis, Épidémiologie des infections chroniques à Coxiella Burnetii sur l'île de la Réunion, une étude rétrospective de, Medecine humaine et pathologie, 2007.

J. Jaubert, F. Naze, and G. Camuset, Seroprevalence of Coxiella burnetii (Q fever) exposure in humans on Reunion Island, Open Forum Infect Dis, vol.6, issue.7, p.227, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02173188

, Production et filières, filières agricoles, filières animales. Elevage

H. Paillat-jarousseau, E. Noujarede, and A. Mouchès, Elevage caprin, rituel hindou et réglementation sanitaire française : tradition, concertation et régulation sur l'ile de La Réunion, Noirois, vol.223, pp.93-104, 2012.

R. Guatteo, A. Joly, and F. Beaudeau, Shedding and serological patterns of dairy cows following abrotions associated with Coxiella burnetii DNA detection, Vet.Microbiol, vol.155, pp.430-433, 2012.

R. Guatteo, H. Seegers, A. F. Taurel, A. Joly, and F. Beaudeau, Prevalence of Coxiella burnetii infection in domestic ruminants: a critical review, Vet Microbiol, vol.149, pp.1-16, 2011.

S. M. Woldeyohannes, C. F. Gilks, P. Baker, N. R. Perkins, and S. Reid, A Seroprevalence of Coxiella burnetii among abattoir and slaughterhouse workers : a meta-analysis, One Health, vol.6, pp.23-28, 2018.

D. Frankel, H. Richet, A. Renvoisé, D. Raoult, and . Fever-in-france, Emerg Infect Dis, vol.17, pp.350-356, 1985.

M. Montes, G. Cilla, D. Vicente, V. Nieto, M. Ercibengoa et al., A Hyperendemic Area of Q Fever, Ann NY Acad Sci, vol.1078, pp.129-132, 1984.

, European Centre for disease prevention and control. Q fever annual epidemiological reportfor2017

C. Bellini, I. Magouras, and C. Chapuis-taillard, Q fever outbreak in the terraced vineyards of Lavaux, New Microbes New Infect, vol.2, pp.93-99, 2014.

M. R. Rahaman, A. Milazzo, H. Marshall, and P. Bi, Is a One Health approach utilized for Q Fever Control? A comprehensive literature review, Int J Environ Res Public Health, vol.16, 2019.

F. S. Dahlgren, J. H. Mcquiston, R. F. Massung, and A. D. Anderson, Q Fever in the United States: summary of case reports from two national surveillance systems, Am J Trop Med Hyg, vol.92, pp.247-255, 2000.

B. Schimmer, D. W. Notermans, and M. G. Harms, Low seroprevalence of Q fever in the Netherlands prior to a series of large outbreaks, Epidemiol infect, vol.140, pp.27-35, 2012.

J. Gardon, J. Héraud, and S. Laventure, Suburban Transmission of Q Fever in French Guiana: Evidence of a Wild Reservoir, J Infect Dis, vol.184, pp.278-284, 2001.
URL : https://hal.archives-ouvertes.fr/pasteur-00607923

C. Eldin, A. Mahamat, M. Demar, P. Abboud, F. Djossou et al., Am J Trop Med Hyg, vol.91, pp.771-776, 2014.

V. Pommier-de-santi, S. Briolant, and A. Mahamat, Q fever epidemic in Cayenne, French Guiana, epidemiologically linked to three-toed sloth, Comp Immunol Microbiol Infect Dis, vol.56, pp.34-38, 2018.

J. A. Crump, Time for a comprehensive approach to the syndrome of fever in the tropics, Trans R Soc Trop Med Hyg, vol.108, pp.61-62, 2014.

T. H. Ta, B. Jimenez, M. Navarro, Y. Meije, F. J. Gonzalez et al., Q fever in returned febrile travelers, J Travel Med, vol.15, pp.126-129, 2008.

C. Melenotte, L. Epelboin, and M. Million, Acute Q fever endocarditis: a paradigm shift following the systematic use of transthoracic echocardiography during acute Q fever, Clin Infect Dis, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02202474

A. Jansen, R. Raijmakers, and S. P. Keijmel, Autoimmunity and B-cell dyscrasia in acute and chronic Q fever: a review of the literature, Eur J Intern Med, vol.54, pp.6-12, 2018.

R. Raijmakers, S. P. Keijmel, and E. Breukers, Long-term effet of cognitive behavioural therapy and doxycycline treatment for patients with Q fever fatigue syndrome : one-year follow-up of the Qure study, J Psychosom Res, vol.116, pp.62-67, 2019.

T. F. Hatchette, M. Hayes, H. Merry, W. F. Schlech, and T. J. Marrie, The effect of C. burnetii infection on the quality of life of patients following an outbreak of Q fever, Epidemiol Infect, vol.130, pp.491-495, 2003.

H. K. Miller, . Binder-am, and A. Peterson, Trends in Q fever serologic testing by immunofluorescence from four large reference laboratories in the United states, Sci Rep, vol.8, p.16670, 2012.

R. Soulard, J. B. Souraud, C. Landais, L. Hemon, A. Gaillard et al., Histopathology of a granulomatous lobular panniculitis in acute Q fever: a case report, J Cutan Pathol, vol.37, pp.870-876, 2010.

C. Melenotte, M. Million, and G. Audoly, B-cell non-Hodgkin lymphoma linked to Coxiella Burnetii, Blood, vol.127, pp.113-121, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01440249

L. Luciani, L. 'ollivier, C. Million, M. Amphoux, B. Edouard et al., Introduction to measurement of avidity of anti-Coxiella burnetii IgG in diagnosis of Q Fever, J Clin Microbiol, vol.57, pp.539-558, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02457088

S. Durupt, M. Puget, J. C. Lega, I. Durieu, and Q. Reynaud, Coxiella burnetii infection (Q fever) mimicking systemic lupus erythematosus : two cases, Lupus, vol.27, pp.1027-1029, 2018.

M. Lefebvre, O. Grossi, and C. Agard, Systemic immune presentations of Coxiella burnetii infection (Q fever), Semin Arthritis Rheum, vol.39, pp.405-409, 2010.

C. H. Lai, W. Sun, and C. H. Lee, The epidemiology and characteristics of Q fever and coinfections with scrub typhus, murine typhus or leptospirosis in Taiwan: A nationwide database study, Zoonoses Public Health, vol.64, pp.517-526, 2016.

C. Eldin, P. Parola, and D. Raoult, Limitations of diagnostic tests for bacterial infections, Med Mal Infect, vol.49, pp.98-101, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02262542

C. Lai, C. Lin, and J. , High Seroprevalence of Mycoplasma pneumoniae IgM in Acute Q Fever by Enzyme-Linked Immunosorbent Assay (ELISA), PLoS ONE, vol.8, issue.10, p.77640, 2013.

M. Vardi, N. Petersil, and A. Keysary, Immunological arousal during acute Q fever infection, Eur J Clin Microbiol Infect Dis, vol.30, pp.1527-1530, 2011.

L. Scola, B. Raoult, and D. , Serological cross-reactions between Bartonella quintana, Bartonella henselae and Coxiella burnetii, J clin microbiol, vol.34, pp.2270-2274, 1996.

H. Lerner and C. Berg, The concept of health in One Health and some practical implications for research and education: what is One Health?, Infect Ecol Epidemiol, vol.5, p.25300, 2015.

J. Bénie-bi-vroh and I. Seck, La mise en oeuvre du concept One Health est-elle une réalité en Afrique ? Société Française Santé publique, vol.28, pp.283-285, 2016.

H. Keune, L. Flandroy, and S. Thys, The need for european Onehealth/ EcoHealth networks. Archives of Public health, vol.75, p.64, 2017.

, One Health Océan indien

. Serment-d'hippocrate,

, Au moment d 'être admise à exercer la médecine, je promets et je jure d'être fidèle aux lois de l'honneur et de la probité

, Mon premier souci sera de rétablir, de préserver ou de promouvoir la santé dans tous ses éléments physiques et mentaux, individuels et sociaux

, Je respecterai toutes les personnes, leur autonomie et leur volonté, sans aucune discrimination selon leur état ou leurs convictions. J'interviendrai pour les protéger si elles sont affaiblies, vulnérables ou menacées dans leur intégrité ou leur dignité. Même sous la contrainte

, Je ne tromperai jamais leur confiance et n'exploiterai pas le pouvoir hérité des circonstances pour forcer les consciences

, Je ne me laisserai pas influencer par la soif du gain ou la recherche de la gloire

, Admise dans l'intimité des personnes, je tairai les secrets qui me seront confiés. Reçue à l'intérieur des maisons, je respecterai les secrets des foyers et ma conduite ne servira pas à corrompre les moeurs

, Je ne prolongerai pas abusivement les agonies. Je ne provoquerai jamais la mort délibérément

, Je n'entreprendrai rien qui dépasse mes compétences. Je les entretiendrai et les perfectionnerai pour assurer au mieux les services qui me seront demandés

, J'apporterai mon aide à mes confrères ainsi qu'à leurs familles dans l'adversité

, Que les hommes et mes confrères m'accordent leur estime si je suis fidèle à mes promesses

, que je sois déshonorée et méprisée si j'y manque