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Master Thesis

Impact immédiat et à long terme d'un programme de réhabilitation par l'activité physique sur la densité minérale osseuse chez des patients atteints de maladies chroniques

Abstract : Background: Regular physical activity (PA) for people with chronic diseases has many benefits, including bone health benefits. Objective: The aim of the study was to assess the immediate and long-term impact of a PA intervention on bone mineral density (BMD) in patients with chronic diseases. Methods: We included patients participating in a 6-week AP program. Body composition (total BMD, hip and lumbar), aerobic capacity (AC), physical capacities (PC), quality of life (QoL) (SF36 questionnaire) and PA level (Ricci & Gagnon questionnaire) were assessed at baseline, after the intervention, and at 6 and 12 months of follow-up. Results: A total of 173 patients were included (median age: 63.2 years, 52.6% female, 35.8% metabolic syndrome) of whom 64.2% were initially inactive. The initial total BMD was positively correlated with peak power (PP, r=0.39), lower limb strength (r=0.15) and negatively correlated with age (r=-0.27), BMI (r=-0.18) and tobacco (r=-0.16). After the program (n=149, 86.1%), the AC, QoL and PC parameters were significantly improved (p<0.01) without changing the BMD (3 sites). After 12 months (n=112, 64.7%) the QoL and some AC (PP, six-minute walk) and PC parameters were improved (p<0.01) without modification of the BMD (3 locations). Among patients followed at 12 months (n=112), 63.8% of initially inactive patients became active. Conclusion: In patients with chronic diseases, a 6-week AP intervention has positive and lasting effects on AC, QoL and PC without significantly increasing BMD.
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Master Thesis
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  • HAL Id : dumas-02486222, version 1

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Clémence Ferrandez. Impact immédiat et à long terme d'un programme de réhabilitation par l'activité physique sur la densité minérale osseuse chez des patients atteints de maladies chroniques. Médecine humaine et pathologie. 2019. ⟨dumas-02486222⟩

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